Name | Number of supported studies | Average coverage | |
---|---|---|---|
peripheral blood | 10 studies | 20% ± 4% | |
lung | 7 studies | 27% ± 9% | |
intestine | 7 studies | 20% ± 8% | |
kidney | 6 studies | 21% ± 4% | |
pancreas | 4 studies | 47% ± 22% | |
brain | 4 studies | 22% ± 6% | |
bone marrow | 3 studies | 16% ± 0% | |
liver | 3 studies | 46% ± 33% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
liver | 100% | 5989.49 | 226 / 226 | 100% | 144.63 | 406 / 406 |
ovary | 100% | 4077.39 | 180 / 180 | 100% | 188.63 | 430 / 430 |
pancreas | 100% | 5391.38 | 328 / 328 | 100% | 135.49 | 178 / 178 |
thymus | 100% | 8153.13 | 653 / 653 | 100% | 155.48 | 605 / 605 |
uterus | 100% | 4056.84 | 170 / 170 | 100% | 184.23 | 459 / 459 |
esophagus | 100% | 6414.35 | 1444 / 1445 | 100% | 158.55 | 183 / 183 |
skin | 100% | 6159.90 | 1809 / 1809 | 100% | 148.63 | 471 / 472 |
intestine | 100% | 5556.75 | 966 / 966 | 100% | 217.71 | 525 / 527 |
adrenal gland | 100% | 9447.47 | 258 / 258 | 100% | 147.32 | 229 / 230 |
brain | 99% | 3555.69 | 2628 / 2642 | 100% | 82.80 | 705 / 705 |
stomach | 100% | 5016.26 | 359 / 359 | 99% | 188.02 | 284 / 286 |
kidney | 100% | 11918.91 | 89 / 89 | 99% | 140.35 | 894 / 901 |
prostate | 100% | 6968.58 | 245 / 245 | 99% | 197.36 | 498 / 502 |
bladder | 100% | 4755.57 | 21 / 21 | 99% | 203.09 | 499 / 504 |
lung | 100% | 5016.45 | 576 / 578 | 99% | 176.66 | 1144 / 1155 |
breast | 100% | 4405.92 | 459 / 459 | 99% | 158.31 | 1102 / 1118 |
eye | 0% | 0 | 0 / 0 | 100% | 130.23 | 80 / 80 |
lymph node | 0% | 0 | 0 / 0 | 100% | 159.49 | 29 / 29 |
peripheral blood | 100% | 52289.60 | 929 / 929 | 0% | 0 | 0 / 0 |
spleen | 100% | 7903.05 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 152.51 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 157.27 | 1 / 1 |
adipose | 100% | 4050.35 | 1203 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 99% | 3641.73 | 1327 / 1335 | 0% | 0 | 0 / 0 |
heart | 99% | 3330.02 | 849 / 861 | 0% | 0 | 0 / 0 |
muscle | 94% | 2050.18 | 756 / 803 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0160007 | Biological process | glutathione import into mitochondrion |
GO_0006810 | Biological process | transport |
GO_0006783 | Biological process | heme biosynthetic process |
GO_0071281 | Biological process | cellular response to iron ion |
GO_0005743 | Cellular component | mitochondrial inner membrane |
GO_0005739 | Cellular component | mitochondrion |
GO_0051537 | Molecular function | 2 iron, 2 sulfur cluster binding |
GO_0034634 | Molecular function | glutathione transmembrane transporter activity |
GO_0046872 | Molecular function | metal ion binding |
Gene name | SLC25A39 |
Protein name | Mitochondrial glutathione transporter SLC25A39 (Solute carrier family 25 member 39) Solute carrier family 25 member 39 Mitochondrial glutathione transporter SLC25A40 (Solute carrier family 25 member 40) Probable mitochondrial glutathione transporter SLC25A39 (Solute carrier family 25 member 39) |
Synonyms | CGI-69 PRO2163 |
Description | FUNCTION: Mitochondrial transporter required for glutathione import into mitochondria . Glutathione, which plays key roles in oxidative metabolism, is produced exclusively in the cytosol and is imported in many organelles . Mitochondrial glutathione is required for the activity and stability of proteins containing iron-sulfur clusters, as well as erythropoiesis . . FUNCTION: Mitochondrial transporter required for glutathione import into mitochondria. Glutathione, which plays key roles in oxidative metabolism, is produced exclusively in the cytosol and is imported in many organelles. Mitochondrial glutathione is required for the activity and stability of proteins containing iron-sulfur clusters, as well as erythropoiesis. . FUNCTION: Mitochondrial transporter required for glutathione import into mitochondria. Glutathione, which plays key roles in oxidative metabolism, is produced exclusively in the cytosol and is imported in many organelles. Mitochondrial glutathione is required for the activity and stability of proteins containing iron-sulfur clusters, as well as erythropoiesis. . FUNCTION: Mitochondrial transporter required for glutathione import into mitochondria. Glutathione, which plays key roles in oxidative metabolism, is produced exclusively in the cytosol and is imported in many organelles. Mitochondrial glutathione is required for the activity and stability of proteins containing iron-sulfur clusters, as well as erythropoiesis. . FUNCTION: Mitochondrial transporter required for glutathione import into mitochondria. Glutathione, which plays key roles in oxidative metabolism, is produced exclusively in the cytosol and is imported in many organelles. Mitochondrial glutathione is required for the activity and stability of proteins containing iron-sulfur clusters, as well as erythropoiesis. . FUNCTION: Mitochondrial transporter required for glutathione import into mitochondria. Glutathione, which plays key roles in oxidative metabolism, is produced exclusively in the cytosol and is imported in many organelles. Mitochondrial glutathione is required for the activity and stability of proteins containing iron-sulfur clusters, as well as erythropoiesis. . FUNCTION: Mitochondrial transporter required for glutathione import into mitochondria. Glutathione, which plays key roles in oxidative metabolism, is produced exclusively in the cytosol and is imported in many organelles. Mitochondrial glutathione is required for the activity and stability of proteins containing iron-sulfur clusters, as well as erythropoiesis. . FUNCTION: Mitochondrial transporter required for glutathione import into mitochondria. Glutathione, which plays key roles in oxidative metabolism, is produced exclusively in the cytosol and is imported in many organelles. Mitochondrial glutathione is required for the activity and stability of proteins containing iron-sulfur clusters, as well as erythropoiesis. . FUNCTION: Mitochondrial transporter required for glutathione import into mitochondria. Glutathione, which plays key roles in oxidative metabolism, is produced exclusively in the cytosol and is imported in many organelles. Mitochondrial glutathione is required for the activity and stability of proteins containing iron-sulfur clusters, as well as erythropoiesis. . |
Accessions | ENST00000585636.5 K7ELM7 K7EKF4 K7EJI2 ENST00000377095.10 [Q9BZJ4-1] Q9BZJ4 K7EQS4 ENST00000537904.6 ENST00000585523.1 K7EQS8 ENST00000586016.5 K7EMW3 K7EMR4 K7EKC2 ENST00000590194.5 [Q9BZJ4-2] ENST00000593166.1 ENST00000586633.5 ENST00000588049.5 B4DFG5 ENST00000592857.5 ENST00000225308.12 [Q9BZJ4-2] ENST00000588767.5 |