Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
breast | 100% | 682.98 | 459 / 459 | 100% | 34.55 | 1114 / 1118 |
lung | 100% | 1539.78 | 578 / 578 | 99% | 33.95 | 1148 / 1155 |
thymus | 100% | 545.89 | 651 / 653 | 100% | 27.80 | 603 / 605 |
skin | 100% | 564.93 | 1803 / 1809 | 100% | 40.33 | 470 / 472 |
bladder | 100% | 612.71 | 21 / 21 | 98% | 32.73 | 493 / 504 |
brain | 93% | 398.49 | 2458 / 2642 | 100% | 34.24 | 705 / 705 |
uterus | 93% | 363.60 | 158 / 170 | 100% | 34.67 | 457 / 459 |
prostate | 98% | 573.80 | 239 / 245 | 94% | 11.58 | 472 / 502 |
esophagus | 92% | 393.78 | 1336 / 1445 | 99% | 26.80 | 181 / 183 |
intestine | 95% | 646.34 | 915 / 966 | 89% | 20.13 | 470 / 527 |
adrenal gland | 100% | 615.57 | 258 / 258 | 83% | 13.54 | 190 / 230 |
stomach | 92% | 371.52 | 329 / 359 | 91% | 26.52 | 259 / 286 |
kidney | 89% | 423.53 | 79 / 89 | 93% | 22.22 | 839 / 901 |
pancreas | 81% | 282.86 | 265 / 328 | 97% | 29.64 | 172 / 178 |
ovary | 43% | 124.23 | 77 / 180 | 100% | 50.04 | 430 / 430 |
liver | 57% | 194.15 | 129 / 226 | 75% | 12.95 | 305 / 406 |
adipose | 100% | 863.97 | 1204 / 1204 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 100% | 20.86 | 80 / 80 |
lymph node | 0% | 0 | 0 / 0 | 100% | 107.88 | 29 / 29 |
peripheral blood | 100% | 10102.77 | 929 / 929 | 0% | 0 | 0 / 0 |
spleen | 100% | 5600.09 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 33.82 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 17.10 | 1 / 1 |
blood vessel | 99% | 908.67 | 1322 / 1335 | 0% | 0 | 0 / 0 |
heart | 83% | 276.25 | 718 / 861 | 0% | 0 | 0 / 0 |
muscle | 20% | 46.99 | 157 / 803 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0006914 | Biological process | autophagy |
GO_0007186 | Biological process | G protein-coupled receptor signaling pathway |
GO_0045471 | Biological process | response to ethanol |
GO_0007264 | Biological process | small GTPase-mediated signal transduction |
GO_0009968 | Biological process | negative regulation of signal transduction |
GO_0005903 | Cellular component | brush border |
GO_0030136 | Cellular component | clathrin-coated vesicle |
GO_0005794 | Cellular component | Golgi apparatus |
GO_0005886 | Cellular component | plasma membrane |
GO_0016020 | Cellular component | membrane |
GO_0001965 | Molecular function | G-protein alpha-subunit binding |
GO_0005515 | Molecular function | protein binding |
GO_0003924 | Molecular function | GTPase activity |
Gene name | RGS19 |
Protein name | Regulator of G-protein signaling 19 (RGS19) (G-alpha-interacting protein) (GAIP) RGS19 protein |
Synonyms | GNAI3IP GAIP |
Description | FUNCTION: Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to G-alpha subfamily 1 members, with the order G(i)a3 > G(i)a1 > G(o)a >> G(z)a/G(i)a2. Activity on G(z)-alpha is inhibited by phosphorylation and palmitoylation of the G-protein. |
Accessions | ENST00000332298.9 ENST00000395042.2 Q6I9S5 P49795 |