RALGAPA1 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
endothelial cell	27 studies	44% ± 19%	Explore
astrocyte	18 studies	47% ± 21%	Explore
oligodendrocyte	15 studies	54% ± 20%	Explore
oligodendrocyte precursor cell	14 studies	49% ± 22%	Explore
pericyte	14 studies	35% ± 18%	Explore
natural killer cell	13 studies	24% ± 7%	Explore
microglial cell	13 studies	43% ± 14%	Explore
glutamatergic neuron	12 studies	55% ± 25%	Explore
fibroblast	12 studies	39% ± 14%	Explore
smooth muscle cell	12 studies	36% ± 12%	Explore
CD8-positive, alpha-beta T cell	11 studies	21% ± 4%	Explore
T cell	10 studies	25% ± 7%	Explore
GABAergic neuron	10 studies	56% ± 25%	Explore
CD4-positive, alpha-beta T cell	10 studies	23% ± 5%	Explore
macrophage	9 studies	35% ± 15%	Explore
regulatory T cell	9 studies	21% ± 4%	Explore
B cell	9 studies	21% ± 6%	Explore
CD16-negative, CD56-bright natural killer cell, human	9 studies	26% ± 6%	Explore
adipocyte	9 studies	37% ± 12%	Explore
effector memory CD8-positive, alpha-beta T cell	8 studies	24% ± 6%	Explore
retinal cone cell	8 studies	55% ± 17%	Explore
epithelial cell	8 studies	40% ± 19%	Explore
CD16-positive, CD56-dim natural killer cell, human	8 studies	22% ± 8%	Explore
gamma-delta T cell	8 studies	27% ± 11%	Explore
neuron	7 studies	47% ± 21%	Explore
amacrine cell	7 studies	36% ± 19%	Explore
retinal ganglion cell	7 studies	40% ± 20%	Explore
mucosal invariant T cell	7 studies	26% ± 8%	Explore
mast cell	7 studies	24% ± 7%	Explore
ciliated cell	7 studies	31% ± 12%	Explore
endothelial cell of lymphatic vessel	7 studies	40% ± 14%	Explore
interneuron	6 studies	62% ± 28%	Explore
retina horizontal cell	6 studies	33% ± 17%	Explore
dendritic cell	6 studies	21% ± 3%	Explore
retinal rod cell	6 studies	40% ± 18%	Explore
CD8-positive, alpha-beta memory T cell	6 studies	29% ± 6%	Explore
mature NK T cell	6 studies	25% ± 6%	Explore
basal cell	6 studies	40% ± 22%	Explore
type I pneumocyte	6 studies	36% ± 12%	Explore
retinal bipolar neuron	5 studies	32% ± 12%	Explore
memory B cell	5 studies	16% ± 1%	Explore
naive B cell	5 studies	19% ± 3%	Explore
cardiac muscle cell	5 studies	42% ± 13%	Explore
endothelial cell of artery	5 studies	23% ± 6%	Explore
Mueller cell	5 studies	38% ± 19%	Explore
monocyte	5 studies	24% ± 5%	Explore
type II pneumocyte	5 studies	38% ± 8%	Explore
leukocyte	4 studies	28% ± 11%	Explore
glial cell	4 studies	31% ± 7%	Explore
granule cell	4 studies	45% ± 8%	Explore
mesothelial cell	4 studies	40% ± 10%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	4 studies	25% ± 3%	Explore
lymphocyte	4 studies	38% ± 17%	Explore
myeloid cell	4 studies	24% ± 7%	Explore
OFF-bipolar cell	4 studies	37% ± 19%	Explore
ON-bipolar cell	4 studies	40% ± 21%	Explore
innate lymphoid cell	4 studies	23% ± 7%	Explore
endothelial cell of vascular tree	4 studies	38% ± 25%	Explore
connective tissue cell	4 studies	23% ± 8%	Explore
myofibroblast cell	4 studies	31% ± 15%	Explore
club cell	4 studies	42% ± 12%	Explore
differentiation-committed oligodendrocyte precursor	3 studies	46% ± 5%	Explore
progenitor cell	3 studies	38% ± 6%	Explore
plasma cell	3 studies	25% ± 5%	Explore
vein endothelial cell	3 studies	41% ± 23%	Explore
GABAergic amacrine cell	3 studies	52% ± 13%	Explore
glycinergic amacrine cell	3 studies	48% ± 8%	Explore
rod bipolar cell	3 studies	49% ± 20%	Explore
effector memory CD4-positive, alpha-beta T cell	3 studies	22% ± 5%	Explore
hepatocyte	3 studies	56% ± 19%	Explore
retinal pigment epithelial cell	3 studies	46% ± 30%	Explore
alveolar macrophage	3 studies	33% ± 6%	Explore
capillary endothelial cell	3 studies	39% ± 11%	Explore
respiratory goblet cell	3 studies	43% ± 16%	Explore
T follicular helper cell	3 studies	19% ± 2%	Explore
muscle cell	3 studies	44% ± 34%	Explore
goblet cell	3 studies	46% ± 33%	Explore
transit amplifying cell	3 studies	40% ± 32%	Explore
brush cell	3 studies	22% ± 4%	Explore
plasmacytoid dendritic cell	3 studies	21% ± 7%	Explore
renal principal cell	3 studies	30% ± 12%	Explore
mucus secreting cell	3 studies	33% ± 7%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
brain	17 studies	52% ± 22%	Explore
eye	8 studies	41% ± 21%	Explore
lung	6 studies	28% ± 8%	Explore
peripheral blood	4 studies	18% ± 4%	Explore
heart	4 studies	36% ± 9%	Explore
adipose	4 studies	30% ± 8%	Explore
kidney	4 studies	28% ± 8%	Explore
liver	3 studies	34% ± 17%	Explore
intestine	3 studies	18% ± 0%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	2253.86	1445 / 1445	99%	9.81	182 / 183
prostate	100%	2512.43	245 / 245	98%	7.92	494 / 502
brain	100%	2243.94	2639 / 2642	98%	8.18	694 / 705
breast	100%	2412.17	459 / 459	95%	8.08	1059 / 1118
thymus	100%	2715.89	653 / 653	91%	4.83	553 / 605
lung	100%	2203.70	578 / 578	91%	5.20	1052 / 1155
adrenal gland	100%	2626.69	258 / 258	89%	6.44	204 / 230
pancreas	100%	1315.06	328 / 328	88%	3.86	157 / 178
stomach	100%	1842.44	359 / 359	86%	5.01	247 / 286
kidney	100%	1430.91	89 / 89	82%	4.38	740 / 901
intestine	100%	2493.92	966 / 966	81%	3.93	427 / 527
ovary	100%	3542.04	180 / 180	80%	3.11	346 / 430
skin	100%	2277.94	1808 / 1809	79%	3.50	372 / 472
uterus	100%	3213.98	170 / 170	76%	3.29	350 / 459
bladder	100%	2335.71	21 / 21	70%	2.88	355 / 504
liver	100%	894.70	226 / 226	38%	1.26	155 / 406
adipose	100%	2128.21	1204 / 1204	0%	0	0 / 0
blood vessel	100%	2631.01	1335 / 1335	0%	0	0 / 0
muscle	100%	1691.34	803 / 803	0%	0	0 / 0
spleen	100%	1524.99	241 / 241	0%	0	0 / 0
heart	97%	1189.56	832 / 861	0%	0	0 / 0
tonsil	0%	0	0 / 0	76%	3.17	34 / 45
eye	0%	0	0 / 0	56%	2.40	45 / 80
lymph node	0%	0	0 / 0	48%	1.60	14 / 29
peripheral blood	42%	470.93	391 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

IV. Literature review

[source]

Gene name	RALGAPA1
Protein name	Alternative protein RALGAPA1 Ral GTPase-activating protein subunit alpha-1 (GAP-related-interacting partner to E12) (GRIPE) (GTPase-activating Rap/Ran-GAP domain-like 1) (Tuberin-like protein 1) (p240) Ral GTPase activating protein catalytic subunit alpha 1
Synonyms	GARNL1 TULIP1 KIAA0884
Description	FUNCTION: Catalytic subunit of the heterodimeric RalGAP1 complex which acts as a GTPase activator for the Ras-like small GTPases RALA and RALB. .
Accessions	ENST00000389698.7 [Q6GYQ0-1] ENST00000637992.1 L8EAR6 ENST00000554259.6 ENST00000307138.10 [Q6GYQ0-2] Q6GYQ0 ENST00000553892.2 [Q6GYQ0-6] H0YJ04 ENST00000554573.5 A0A1B0GUI1 H0YJB5 A0A7P0TAR5 ENST00000680220.1 ENST00000382366.7 [Q6GYQ0-7]

GO_0051056	Biological process	regulation of small GTPase mediated signal transduction
GO_0090630	Biological process	activation of GTPase activity
GO_0005737	Cellular component	cytoplasm
GO_0005634	Cellular component	nucleus
GO_0046982	Molecular function	protein heterodimerization activity
GO_0005096	Molecular function	GTPase activator activity

RALGAPA1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review