PSMD6 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0043161Biological processproteasome-mediated ubiquitin-dependent protein catabolic process
GO_0000502Cellular componentproteasome complex
GO_1904813Cellular componentficolin-1-rich granule lumen
GO_0005654Cellular componentnucleoplasm
GO_0005829Cellular componentcytosol
GO_0005576Cellular componentextracellular region
GO_0005838Cellular componentproteasome regulatory particle
GO_0022624Cellular componentproteasome accessory complex
GO_0034774Cellular componentsecretory granule lumen
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene namePSMD6
Protein name26S proteasome non-ATPase regulatory subunit 6 (26S proteasome regulatory subunit RPN7) (26S proteasome regulatory subunit S10) (Breast cancer-associated protein SGA-113M) (Phosphonoformate immuno-associated protein 4) (Proteasome regulatory particle subunit p44S10) (p42A)
Proteasome 26S subunit, non-ATPase 6
26S proteasome non-ATPase regulatory subunit 6
SynonymshCG_23509
PFAAP4
KIAA0107
DescriptionFUNCTION: Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. .

AccessionsENST00000492933.5 [Q15008-4]
ENST00000480205.5
ENST00000478185.1
H7C531
ENST00000295901.9 [Q15008-1]
B3KT66
Q15008
C9J7B7
ENST00000394431.6 [Q15008-2]
C9J0E9
ENST00000497323.5
ENST00000482510.5 [Q15008-3]