PLAC8 report

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I. Expression across cell types

Cell ontologyData table

Name	Number of supported studies	Average coverage
natural killer cell	42 studies	56% ± 19%	Explore
B cell	36 studies	40% ± 17%	Explore
plasmacytoid dendritic cell	29 studies	84% ± 16%	Explore
classical monocyte	25 studies	36% ± 16%	Explore
CD4-positive, alpha-beta T cell	23 studies	33% ± 15%	Explore
non-classical monocyte	22 studies	52% ± 13%	Explore
CD8-positive, alpha-beta T cell	21 studies	31% ± 15%	Explore
monocyte	20 studies	37% ± 19%	Explore
naive B cell	19 studies	35% ± 13%	Explore
T cell	18 studies	28% ± 14%	Explore
ciliated cell	18 studies	55% ± 21%	Explore
conventional dendritic cell	17 studies	35% ± 21%	Explore
mature NK T cell	17 studies	44% ± 16%	Explore
memory B cell	17 studies	38% ± 11%	Explore
CD16-negative, CD56-bright natural killer cell, human	15 studies	55% ± 24%	Explore
CD16-positive, CD56-dim natural killer cell, human	15 studies	66% ± 15%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	15 studies	31% ± 12%	Explore
gamma-delta T cell	14 studies	37% ± 12%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	11 studies	37% ± 17%	Explore
dendritic cell	11 studies	31% ± 14%	Explore
mucosal invariant T cell	11 studies	30% ± 8%	Explore
type I pneumocyte	10 studies	32% ± 14%	Explore
respiratory goblet cell	7 studies	39% ± 16%	Explore
enterocyte	7 studies	46% ± 20%	Explore
goblet cell	7 studies	28% ± 6%	Explore
innate lymphoid cell	7 studies	39% ± 15%	Explore
epithelial cell	6 studies	39% ± 16%	Explore
macrophage	6 studies	33% ± 17%	Explore
myeloid cell	6 studies	34% ± 20%	Explore
CD8-positive, alpha-beta memory T cell	6 studies	29% ± 9%	Explore
hematopoietic precursor cell	5 studies	61% ± 28%	Explore
club cell	5 studies	36% ± 18%	Explore
effector memory CD8-positive, alpha-beta T cell	5 studies	47% ± 19%	Explore
hematopoietic stem cell	5 studies	30% ± 4%	Explore
pro-B cell	5 studies	23% ± 7%	Explore
progenitor cell	5 studies	45% ± 24%	Explore
deuterosomal cell	4 studies	38% ± 4%	Explore
secretory cell	4 studies	29% ± 6%	Explore
squamous epithelial cell	4 studies	44% ± 22%	Explore
plasmablast	4 studies	38% ± 13%	Explore
leukocyte	4 studies	28% ± 5%	Explore
basal cell	4 studies	33% ± 10%	Explore
immature B cell	4 studies	55% ± 8%	Explore
intermediate monocyte	4 studies	55% ± 26%	Explore
brush cell	4 studies	29% ± 16%	Explore
regulatory T cell	4 studies	18% ± 1%	Explore
CD4-positive, alpha-beta memory T cell	4 studies	28% ± 10%	Explore
double negative thymocyte	4 studies	42% ± 7%	Explore
effector CD8-positive, alpha-beta T cell	3 studies	27% ± 11%	Explore
mononuclear phagocyte	3 studies	34% ± 2%	Explore
extravillous trophoblast	3 studies	74% ± 8%	Explore
common myeloid progenitor	3 studies	54% ± 12%	Explore
plasma cell	3 studies	43% ± 24%	Explore
precursor B cell	3 studies	31% ± 13%	Explore
endothelial cell of sinusoid	3 studies	22% ± 4%	Explore
endothelial cell	3 studies	48% ± 23%	Explore
effector memory CD4-positive, alpha-beta T cell	3 studies	31% ± 9%	Explore
granulocyte monocyte progenitor cell	3 studies	74% ± 27%	Explore
T follicular helper cell	3 studies	42% ± 11%	Explore
group 3 innate lymphoid cell	3 studies	31% ± 8%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	3 studies	41% ± 6%	Explore
central memory CD4-positive, alpha-beta T cell	3 studies	30% ± 2%	Explore

II. Expression across tissues

sc-RNAseq dataData table

Name	Number of supported studies	Average coverage
peripheral blood	18 studies	41% ± 12%	Explore
lung	9 studies	28% ± 12%	Explore
intestine	8 studies	22% ± 6%	Explore
placenta	4 studies	31% ± 17%	Explore
liver	4 studies	22% ± 4%	Explore
bone marrow	3 studies	29% ± 8%	Explore
lymph node	3 studies	32% ± 9%	Explore

Bulk RNAseq dataData table

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
lung	99%	1313.41	570 / 578	73%	24.62	839 / 1155
stomach	69%	1176.34	246 / 359	85%	37.75	242 / 286
intestine	55%	2492.45	529 / 966	86%	41.94	452 / 527
esophagus	38%	933.16	543 / 1445	68%	35.34	125 / 183
peripheral blood	100%	9363.66	929 / 929	0%	0	0 / 0
spleen	100%	4870.71	241 / 241	0%	0	0 / 0
ureter	0%	0	0 / 0	100%	6.56	1 / 1
pancreas	0%	0.71	1 / 328	88%	41.94	156 / 178
tonsil	0%	0	0 / 0	82%	50.47	37 / 45
lymph node	0%	0	0 / 0	66%	12.50	19 / 29
uterus	4%	24.74	7 / 170	50%	19.08	230 / 459
liver	44%	162.62	100 / 226	8%	1.62	34 / 406
bladder	0%	0	0 / 21	52%	14.02	263 / 504
thymus	6%	29.19	36 / 653	27%	4.72	164 / 605
prostate	17%	56.26	41 / 245	7%	0.41	34 / 502
kidney	8%	25.75	7 / 89	15%	1.38	137 / 901
breast	7%	47.25	30 / 459	15%	1.41	171 / 1118
skin	0%	1.71	8 / 1809	17%	2.30	80 / 472
brain	3%	12.65	83 / 2642	14%	1.40	100 / 705
adipose	11%	44.09	134 / 1204	0%	0	0 / 0
ovary	0%	0	0 / 180	7%	0.50	30 / 430
adrenal gland	2%	4.71	5 / 258	1%	0.17	3 / 230
heart	2%	6.39	18 / 861	0%	0	0 / 0
blood vessel	2%	8.85	24 / 1335	0%	0	0 / 0
muscle	0%	0.36	1 / 803	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
eye	0%	0	0 / 0	0%	0	0 / 80
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0