PHYKPL | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
fibroblast	16 studies	23% ± 7%	Explore
B cell	15 studies	22% ± 4%	Explore
endothelial cell	15 studies	24% ± 7%	Explore
plasmacytoid dendritic cell	14 studies	28% ± 10%	Explore
T cell	13 studies	19% ± 3%	Explore
natural killer cell	13 studies	21% ± 4%	Explore
CD4-positive, alpha-beta T cell	12 studies	19% ± 4%	Explore
naive B cell	11 studies	20% ± 4%	Explore
regulatory T cell	11 studies	18% ± 3%	Explore
astrocyte	10 studies	29% ± 14%	Explore
CD16-negative, CD56-bright natural killer cell, human	9 studies	20% ± 6%	Explore
adipocyte	9 studies	45% ± 16%	Explore
macrophage	9 studies	26% ± 11%	Explore
endothelial cell of lymphatic vessel	9 studies	24% ± 7%	Explore
memory B cell	8 studies	19% ± 2%	Explore
non-classical monocyte	8 studies	24% ± 9%	Explore
gamma-delta T cell	8 studies	25% ± 7%	Explore
microglial cell	8 studies	30% ± 12%	Explore
CD8-positive, alpha-beta T cell	8 studies	20% ± 3%	Explore
CD8-positive, alpha-beta memory T cell	7 studies	19% ± 3%	Explore
CD16-positive, CD56-dim natural killer cell, human	7 studies	18% ± 4%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	7 studies	19% ± 4%	Explore
pericyte	7 studies	20% ± 4%	Explore
myeloid cell	7 studies	21% ± 4%	Explore
epithelial cell	7 studies	30% ± 11%	Explore
dendritic cell	7 studies	26% ± 14%	Explore
T follicular helper cell	7 studies	18% ± 2%	Explore
classical monocyte	6 studies	23% ± 10%	Explore
effector memory CD8-positive, alpha-beta T cell	6 studies	21% ± 3%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	6 studies	19% ± 3%	Explore
mast cell	6 studies	21% ± 5%	Explore
abnormal cell	6 studies	24% ± 9%	Explore
oligodendrocyte	6 studies	30% ± 10%	Explore
mature NK T cell	5 studies	24% ± 6%	Explore
ciliated cell	5 studies	20% ± 5%	Explore
type I pneumocyte	5 studies	20% ± 6%	Explore
goblet cell	5 studies	25% ± 10%	Explore
CD4-positive, alpha-beta memory T cell	4 studies	20% ± 5%	Explore
exhausted T cell	4 studies	21% ± 5%	Explore
immature B cell	4 studies	20% ± 4%	Explore
cardiac muscle cell	4 studies	18% ± 2%	Explore
lymphocyte	4 studies	27% ± 4%	Explore
glutamatergic neuron	4 studies	35% ± 18%	Explore
oligodendrocyte precursor cell	4 studies	32% ± 9%	Explore
monocyte	4 studies	27% ± 3%	Explore
mucosal invariant T cell	4 studies	19% ± 4%	Explore
conventional dendritic cell	3 studies	39% ± 17%	Explore
precursor B cell	3 studies	23% ± 6%	Explore
plasma cell	3 studies	28% ± 9%	Explore
mononuclear phagocyte	3 studies	21% ± 3%	Explore
Mueller cell	3 studies	17% ± 1%	Explore
hepatocyte	3 studies	42% ± 26%	Explore
type II pneumocyte	3 studies	23% ± 4%	Explore
GABAergic neuron	3 studies	33% ± 11%	Explore
effector memory CD4-positive, alpha-beta T cell	3 studies	22% ± 5%	Explore
innate lymphoid cell	3 studies	19% ± 2%	Explore
enterocyte	3 studies	18% ± 2%	Explore
club cell	3 studies	23% ± 5%	Explore
myofibroblast cell	3 studies	23% ± 5%	Explore
alveolar macrophage	3 studies	22% ± 7%	Explore
smooth muscle cell	3 studies	22% ± 3%	Explore
group 3 innate lymphoid cell	3 studies	33% ± 16%	Explore
brush cell	3 studies	19% ± 3%	Explore
neuron	3 studies	31% ± 11%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
peripheral blood	8 studies	21% ± 7%	Explore
brain	7 studies	30% ± 15%	Explore
lung	5 studies	20% ± 5%	Explore
heart	4 studies	20% ± 2%	Explore
lymph node	4 studies	20% ± 4%	Explore
adipose	4 studies	35% ± 18%	Explore
kidney	3 studies	17% ± 2%	Explore
liver	3 studies	28% ± 12%	Explore
intestine	3 studies	23% ± 7%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	2464.83	1445 / 1445	100%	12.58	183 / 183
intestine	100%	4322.96	966 / 966	100%	13.66	526 / 527
prostate	100%	4437.56	245 / 245	100%	14.94	501 / 502
ovary	100%	4141.02	180 / 180	100%	13.73	429 / 430
thymus	100%	5783.95	653 / 653	100%	17.50	603 / 605
lung	100%	3883.98	578 / 578	100%	12.44	1151 / 1155
stomach	100%	2733.28	359 / 359	100%	12.15	285 / 286
liver	100%	5136.84	226 / 226	100%	12.44	404 / 406
pancreas	100%	2331.41	328 / 328	99%	14.12	177 / 178
uterus	100%	4143.92	170 / 170	99%	10.79	455 / 459
kidney	100%	3993.16	89 / 89	99%	24.10	891 / 901
breast	100%	3769.26	459 / 459	99%	11.55	1105 / 1118
bladder	100%	3065.14	21 / 21	99%	10.92	498 / 504
adrenal gland	100%	2732.09	258 / 258	97%	7.51	222 / 230
skin	100%	1861.08	1805 / 1809	95%	8.96	447 / 472
brain	92%	1033.29	2440 / 2642	100%	12.56	704 / 705
adipose	100%	4088.95	1204 / 1204	0%	0	0 / 0
lymph node	0%	0	0 / 0	100%	17.92	29 / 29
spleen	100%	6286.65	241 / 241	0%	0	0 / 0
blood vessel	100%	2258.29	1332 / 1335	0%	0	0 / 0
muscle	100%	1969.21	800 / 803	0%	0	0 / 0
heart	99%	2060.77	852 / 861	0%	0	0 / 0
peripheral blood	99%	2998.11	918 / 929	0%	0	0 / 0
tonsil	0%	0	0 / 0	98%	9.31	44 / 45
eye	0%	0	0 / 0	90%	7.43	72 / 80
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

III. Associated gene sets

GO_0005759	Cellular component	mitochondrial matrix
GO_0016829	Molecular function	lyase activity
GO_0042802	Molecular function	identical protein binding
GO_0008483	Molecular function	transaminase activity
GO_0005515	Molecular function	protein binding
GO_0030170	Molecular function	pyridoxal phosphate binding

IV. Literature review

[source]

Gene name	PHYKPL
Protein name	5-phosphohydroxy-L-lysine phospho-lyase 5-phosphohydroxy-L-lysine phospho-lyase (EC 4.2.3.134) (Alanine--glyoxylate aminotransferase 2-like 2)
Synonyms	AGXT2L2 PP9286
Description	FUNCTION: Catalyzes the pyridoxal-phosphate-dependent breakdown of 5-phosphohydroxy-L-lysine, converting it to ammonia, inorganic phosphate and 2-aminoadipate semialdehyde. .
Accessions	H7BXR0 H0YAK5 D6RD89 H0Y9N3 ENST00000476170.2 D6RAR0 ENST00000308158.10 [Q8IUZ5-1] ENST00000323594.8 H7BYK2 ENST00000393488.2 ENST00000493197.5 ENST00000474052.5 D6RCB8 ENST00000506045.1 ENST00000510913.5 Q8IUZ5

PHYKPL report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review