NFIB report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0031099Biological processregeneration
GO_0021846Biological processcell proliferation in forebrain
GO_0061141Biological processlung ciliated cell differentiation
GO_0060510Biological processtype II pneumocyte differentiation
GO_0006357Biological processregulation of transcription by RNA polymerase II
GO_0009617Biological processresponse to bacterium
GO_0010001Biological processglial cell differentiation
GO_1902894Biological processnegative regulation of miRNA transcription
GO_0002062Biological processchondrocyte differentiation
GO_0048665Biological processneuron fate specification
GO_0060041Biological processretina development in camera-type eye
GO_0072089Biological processstem cell proliferation
GO_0006260Biological processDNA replication
GO_2000647Biological processnegative regulation of stem cell proliferation
GO_0060509Biological processtype I pneumocyte differentiation
GO_0071679Biological processcommissural neuron axon guidance
GO_0060486Biological processclub cell differentiation
GO_0021960Biological processanterior commissure morphogenesis
GO_0045893Biological processpositive regulation of DNA-templated transcription
GO_0010458Biological processexit from mitosis
GO_0002067Biological processglandular epithelial cell differentiation
GO_0019827Biological processstem cell population maintenance
GO_0021740Biological processprincipal sensory nucleus of trigeminal nerve development
GO_0007420Biological processbrain development
GO_0030902Biological processhindbrain development
GO_0021780Biological processglial cell fate specification
GO_0010467Biological processgene expression
GO_0001894Biological processtissue homeostasis
GO_2000795Biological processnegative regulation of epithelial cell proliferation involved in lung morphogenesis
GO_0060689Biological processcell differentiation involved in salivary gland development
GO_2000791Biological processnegative regulation of mesenchymal cell proliferation involved in lung development
GO_0009611Biological processresponse to wounding
GO_0060662Biological processsalivary gland cavitation
GO_0014009Biological processglial cell proliferation
GO_0045944Biological processpositive regulation of transcription by RNA polymerase II
GO_0005654Cellular componentnucleoplasm
GO_0001650Cellular componentfibrillar center
GO_0044300Cellular componentcerebellar mossy fiber
GO_0000785Cellular componentchromatin
GO_0005634Cellular componentnucleus
GO_0003677Molecular functionDNA binding
GO_0000978Molecular functionRNA polymerase II cis-regulatory region sequence-specific DNA binding
GO_0001228Molecular functionDNA-binding transcription activator activity, RNA polymerase II-specific
GO_0000981Molecular functionDNA-binding transcription factor activity, RNA polymerase II-specific
GO_1990837Molecular functionsequence-specific double-stranded DNA binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameNFIB
Protein nameNuclear factor 1 B-type (CCAAT-box-binding transcription factor) (Nuclear factor I/B) (TGGCA-binding protein)
Nuclear factor 1 B-type (NF1-B) (Nuclear factor 1/B) (CCAAT-box-binding transcription factor) (CTF) (Nuclear factor I/B) (NF-I/B) (NFI-B) (TGGCA-binding protein)
Nuclear factor I B
Nuclear factor 1
SynonymshCG_1742080
DescriptionFUNCTION: Transcriptional activator of GFAP, essential for proper brain development . Recognizes and binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication. .

FUNCTION: Recognizes and binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication. .

FUNCTION: Recognizes and binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication. .

FUNCTION: Recognizes and binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication. .

FUNCTION: Recognizes and binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication. .

FUNCTION: Recognizes and binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication. .

FUNCTION: Recognizes and binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication. .

FUNCTION: Recognizes and binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication. .

FUNCTION: Recognizes and binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication. .

FUNCTION: Recognizes and binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication. .

FUNCTION: Recognizes and binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication. .

FUNCTION: Recognizes and binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication. .

AccessionsA0A1B0GU97
ENST00000397579.6
A0A1B0GTC1
Q5VW31
O00712
ENST00000637640.1
A0A2R8Y7V8
U3KQE8
ENST00000380921.3
U3KPY9
Q5VW28
A0A1B0GW37
ENST00000636063.1
A0A1B0GWB8
ENST00000637742.1
ENST00000397575.7
A0A0A0MRX8
ENST00000636432.1
A0A1B0GWI9
ENST00000380934.8
ENST00000646622.1
ENST00000493697.1
Q5VW30
ENST00000380953.6 [O00712-5]
ENST00000543693.5 [O00712-6]
ENST00000636735.1
A0A1B0GWJ4
Q5VW27
ENST00000380959.7 [O00712-1]
A0A0S2Z4H3
Q5VW26
ENST00000380924.1
ENST00000606230.2
A0A1B0GVN4
ENST00000636057.1
ENST00000397581.7
Q5W0Y9
ENST00000635877.1