NDUFS2 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0006120Biological processmitochondrial electron transport, NADH to ubiquinone
GO_0055085Biological processtransmembrane transport
GO_0061351Biological processneural precursor cell proliferation
GO_0042776Biological processproton motive force-driven mitochondrial ATP synthesis
GO_0022008Biological processneurogenesis
GO_0042063Biological processgliogenesis
GO_0071453Biological processcellular response to oxygen levels
GO_0032981Biological processmitochondrial respiratory chain complex I assembly
GO_0042775Biological processmitochondrial ATP synthesis coupled electron transport
GO_0009060Biological processaerobic respiration
GO_0006979Biological processresponse to oxidative stress
GO_0005739Cellular componentmitochondrion
GO_0005654Cellular componentnucleoplasm
GO_0005743Cellular componentmitochondrial inner membrane
GO_0005759Cellular componentmitochondrial matrix
GO_0045271Cellular componentrespiratory chain complex I
GO_0009055Molecular functionelectron transfer activity
GO_0019826Molecular functionoxygen sensor activity
GO_0051287Molecular functionNAD binding
GO_0003954Molecular functionNADH dehydrogenase activity
GO_0031625Molecular functionubiquitin protein ligase binding
GO_0048038Molecular functionquinone binding
GO_0008137Molecular functionNADH dehydrogenase (ubiquinone) activity
GO_0046872Molecular functionmetal ion binding
GO_0005515Molecular functionprotein binding
GO_0051539Molecular function4 iron, 4 sulfur cluster binding

IV. Literature review

[source]
Gene nameNDUFS2
Protein nameNADH-ubiquinone oxidoreductase NDUFS2 subunit
NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial (Complex I-49kD) (NADH-ubiquinone oxidoreductase 49 kDa subunit)
NADH:ubiquinone oxidoreductase core subunit S2
NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial (EC 7.1.1.2) (Complex I-49kD) (CI-49kD) (NADH-ubiquinone oxidoreductase 49 kDa subunit)
Synonyms
DescriptionFUNCTION: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor . Essential for the catalytic activity of complex I . Essential for the assembly of complex I (By similarity). Redox-sensitive, critical component of the oxygen-sensing pathway in the pulmonary vasculature which plays a key role in acute pulmonary oxygen-sensing and hypoxic pulmonary vasoconstriction . Plays an important role in carotid body sensing of hypoxia (By similarity). Essential for glia-like neural stem and progenitor cell proliferation, differentiation and subsequent oligodendrocyte or neuronal maturation (By similarity). .

AccessionsENST00000677547.1
ENST00000677653.1
ENST00000678783.1
ENST00000677579.1
A0A7I2V5E2
Q9HC12
A0A7I2V4W5
ENST00000679218.1
ENST00000676600.1 [O75306-1]
ENST00000678793.1
Q9HC11
ENST00000678507.1 [O75306-1]
ENST00000678911.1
ENST00000676972.1 [O75306-1]
A0A7I2V410
ENST00000677846.1
ENST00000677550.1 [O75306-2]
A0A7I2V5X7
A0A7I2V596
ENST00000367993.7 [O75306-1]
ENST00000677453.1
A0A7I2V3J6
ENST00000679064.1
A0A7I2V5G4
A0A7I2V2P1
ENST00000677063.1
ENST00000677948.1
ENST00000678511.1 [O75306-1]
ENST00000676583.1
O75306
A0A7I2YQD8
ENST00000392179.5 [O75306-2]
ENST00000678880.1
ENST00000677138.1
A0A7I2V5D5
ENST00000679239.1
ENST00000677045.1
A0A7I2V2B9
ENST00000677837.1
ENST00000679176.1 [O75306-2]
ENST00000679142.1
ENST00000678559.1
ENST00000677081.1
ENST00000678605.1 [O75306-2]
A0A7I2V4X8
ENST00000678532.1
ENST00000679169.1
A0A7I2V517
ENST00000677457.1 [O75306-2]
ENST00000679282.1
A0A7I2V630
A0A7I2YQG7
A0A7I2YQX7
A0A7I2V4G5
ENST00000677231.1
ENST00000676795.1
ENST00000678982.1
ENST00000677613.1