Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| endothelial cell | 33 studies | 44% ± 21% | |
| pericyte | 22 studies | 40% ± 21% | |
| fibroblast | 20 studies | 41% ± 20% | |
| astrocyte | 19 studies | 70% ± 18% | |
| smooth muscle cell | 16 studies | 38% ± 17% | |
| macrophage | 16 studies | 41% ± 22% | |
| oligodendrocyte precursor cell | 16 studies | 62% ± 22% | |
| oligodendrocyte | 15 studies | 56% ± 17% | |
| microglial cell | 15 studies | 59% ± 15% | |
| glutamatergic neuron | 12 studies | 62% ± 25% | |
| GABAergic neuron | 11 studies | 57% ± 23% | |
| epithelial cell | 10 studies | 42% ± 22% | |
| capillary endothelial cell | 9 studies | 30% ± 18% | |
| adipocyte | 9 studies | 61% ± 12% | |
| mast cell | 9 studies | 30% ± 11% | |
| myeloid cell | 8 studies | 32% ± 13% | |
| basal cell | 8 studies | 39% ± 23% | |
| ciliated cell | 8 studies | 33% ± 14% | |
| endothelial cell of lymphatic vessel | 8 studies | 43% ± 16% | |
| neuron | 7 studies | 46% ± 21% | |
| interneuron | 7 studies | 56% ± 26% | |
| retinal ganglion cell | 7 studies | 59% ± 25% | |
| dendritic cell | 7 studies | 40% ± 10% | |
| mesothelial cell | 7 studies | 43% ± 18% | |
| T cell | 7 studies | 30% ± 11% | |
| type I pneumocyte | 7 studies | 39% ± 16% | |
| B cell | 6 studies | 29% ± 12% | |
| retinal cone cell | 6 studies | 37% ± 20% | |
| CD4-positive, alpha-beta T cell | 6 studies | 22% ± 6% | |
| type II pneumocyte | 6 studies | 41% ± 12% | |
| CD8-positive, alpha-beta T cell | 5 studies | 21% ± 5% | |
| cardiac muscle cell | 5 studies | 58% ± 14% | |
| endothelial cell of artery | 5 studies | 27% ± 10% | |
| Mueller cell | 5 studies | 53% ± 22% | |
| retina horizontal cell | 5 studies | 44% ± 18% | |
| endothelial cell of vascular tree | 5 studies | 38% ± 21% | |
| natural killer cell | 5 studies | 29% ± 9% | |
| monocyte | 5 studies | 42% ± 8% | |
| goblet cell | 5 studies | 33% ± 26% | |
| club cell | 5 studies | 42% ± 14% | |
| classical monocyte | 4 studies | 20% ± 5% | |
| glial cell | 4 studies | 41% ± 11% | |
| granule cell | 4 studies | 50% ± 16% | |
| plasma cell | 4 studies | 36% ± 7% | |
| retinal pigment epithelial cell | 4 studies | 46% ± 26% | |
| vein endothelial cell | 4 studies | 42% ± 19% | |
| lymphocyte | 4 studies | 32% ± 13% | |
| OFF-bipolar cell | 4 studies | 44% ± 18% | |
| ON-bipolar cell | 4 studies | 44% ± 19% | |
| amacrine cell | 4 studies | 50% ± 10% | |
| retinal rod cell | 4 studies | 44% ± 7% | |
| hepatocyte | 4 studies | 65% ± 20% | |
| muscle cell | 4 studies | 47% ± 26% | |
| endothelial cell of sinusoid | 3 studies | 31% ± 12% | |
| hepatic stellate cell | 3 studies | 52% ± 20% | |
| glomerular endothelial cell | 3 studies | 19% ± 2% | |
| differentiation-committed oligodendrocyte precursor | 3 studies | 62% ± 7% | |
| GABAergic interneuron | 3 studies | 50% ± 5% | |
| progenitor cell | 3 studies | 39% ± 4% | |
| precursor B cell | 3 studies | 17% ± 1% | |
| CD16-negative, CD56-bright natural killer cell, human | 3 studies | 22% ± 3% | |
| endocardial cell | 3 studies | 50% ± 24% | |
| mononuclear phagocyte | 3 studies | 33% ± 11% | |
| retinal bipolar neuron | 3 studies | 30% ± 10% | |
| GABAergic amacrine cell | 3 studies | 50% ± 15% | |
| glycinergic amacrine cell | 3 studies | 43% ± 8% | |
| rod bipolar cell | 3 studies | 40% ± 19% | |
| cholangiocyte | 3 studies | 63% ± 8% | |
| abnormal cell | 3 studies | 43% ± 18% | |
| neural progenitor cell | 3 studies | 44% ± 17% | |
| connective tissue cell | 3 studies | 36% ± 14% | |
| ependymal cell | 3 studies | 67% ± 11% | |
| adventitial cell | 3 studies | 31% ± 14% | |
| alveolar macrophage | 3 studies | 47% ± 8% | |
| myofibroblast cell | 3 studies | 43% ± 18% | |
| respiratory goblet cell | 3 studies | 45% ± 14% | |
| Schwann cell | 3 studies | 51% ± 27% | |
| leukocyte | 3 studies | 56% ± 9% | |
| kidney distal convoluted tubule epithelial cell | 3 studies | 31% ± 13% | |
| kidney loop of Henle epithelial cell | 3 studies | 37% ± 15% | |
| mucus secreting cell | 3 studies | 46% ± 11% | |
| regulatory T cell | 3 studies | 22% ± 5% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| brain | 18 studies | 58% ± 20% | |
| lung | 6 studies | 36% ± 12% | |
| eye | 6 studies | 47% ± 21% | |
| heart | 5 studies | 45% ± 14% | |
| peripheral blood | 3 studies | 19% ± 1% | |
| liver | 3 studies | 45% ± 16% | |
| intestine | 3 studies | 20% ± 2% | |
| adipose | 3 studies | 51% ± 17% | |
| kidney | 3 studies | 40% ± 7% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| prostate | 100% | 3306.62 | 245 / 245 | 100% | 15.91 | 501 / 502 |
| esophagus | 100% | 2589.83 | 1445 / 1445 | 99% | 13.25 | 182 / 183 |
| lung | 100% | 3301.83 | 578 / 578 | 99% | 11.37 | 1144 / 1155 |
| ovary | 100% | 3207.15 | 180 / 180 | 99% | 7.05 | 425 / 430 |
| brain | 99% | 1752.19 | 2617 / 2642 | 100% | 21.87 | 703 / 705 |
| breast | 100% | 3697.19 | 459 / 459 | 98% | 14.24 | 1101 / 1118 |
| intestine | 100% | 2522.97 | 966 / 966 | 98% | 9.67 | 514 / 527 |
| stomach | 100% | 2114.51 | 358 / 359 | 98% | 11.31 | 279 / 286 |
| skin | 100% | 3254.60 | 1808 / 1809 | 96% | 13.99 | 454 / 472 |
| pancreas | 99% | 1332.46 | 324 / 328 | 97% | 8.72 | 172 / 178 |
| thymus | 100% | 3334.43 | 653 / 653 | 95% | 8.89 | 577 / 605 |
| uterus | 100% | 3236.09 | 170 / 170 | 94% | 7.57 | 432 / 459 |
| bladder | 100% | 2685.86 | 21 / 21 | 93% | 8.08 | 469 / 504 |
| kidney | 100% | 1950.61 | 89 / 89 | 93% | 11.60 | 838 / 901 |
| adrenal gland | 100% | 3134.87 | 258 / 258 | 89% | 7.43 | 205 / 230 |
| liver | 100% | 1385.47 | 225 / 226 | 77% | 5.03 | 314 / 406 |
| adipose | 100% | 3787.00 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 100% | 3337.94 | 1335 / 1335 | 0% | 0 | 0 / 0 |
| muscle | 100% | 2977.13 | 803 / 803 | 0% | 0 | 0 / 0 |
| spleen | 100% | 1892.88 | 241 / 241 | 0% | 0 | 0 / 0 |
| peripheral blood | 95% | 1998.05 | 886 / 929 | 0% | 0 | 0 / 0 |
| heart | 95% | 2050.87 | 821 / 861 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 89% | 7.66 | 40 / 45 |
| lymph node | 0% | 0 | 0 / 0 | 86% | 6.16 | 25 / 29 |
| eye | 0% | 0 | 0 / 0 | 84% | 6.75 | 67 / 80 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0007165 | Biological process | signal transduction |
| GO_0008360 | Biological process | regulation of cell shape |
| GO_0030036 | Biological process | actin cytoskeleton organization |
| GO_0002090 | Biological process | regulation of receptor internalization |
| GO_0007160 | Biological process | cell-matrix adhesion |
| GO_0001726 | Cellular component | ruffle |
| GO_0000151 | Cellular component | ubiquitin ligase complex |
| GO_0005654 | Cellular component | nucleoplasm |
| GO_0005829 | Cellular component | cytosol |
| GO_0005938 | Cellular component | cell cortex |
| GO_0098794 | Cellular component | postsynapse |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0042803 | Molecular function | protein homodimerization activity |
| GO_0042802 | Molecular function | identical protein binding |
| GO_0005515 | Molecular function | protein binding |
| Gene name | MKLN1 |
| Protein name | Muskelin 1 Muskelin |
| Synonyms | |
| Description | FUNCTION: Component of the CTLH E3 ubiquitin-protein ligase complex that selectively accepts ubiquitin from UBE2H and mediates ubiquitination and subsequent proteasomal degradation of the transcription factor HBP1 . Required for internalization of the GABA receptor GABRA1 from the cell membrane via endosomes and subsequent GABRA1 degradation (By similarity). Acts as a mediator of cell spreading and cytoskeletal responses to the extracellular matrix component THBS1 . . |
| Accessions | C9J7E8 ENST00000446815.5 F8WEY7 C9JWX9 ENST00000416992.6 C9JVL5 ENST00000352689.11 [Q9UL63-1] ENST00000421797.6 C9JXB0 ENST00000429546.5 Q9UL63 ENST00000458153.5 |