MAGED2 report

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I. Expression across cell types

Cell ontologyData table

Name	Number of supported studies	Average coverage
fibroblast	34 studies	43% ± 25%	Explore
endothelial cell	29 studies	40% ± 22%	Explore
pericyte	27 studies	48% ± 21%	Explore
smooth muscle cell	22 studies	48% ± 23%	Explore
ciliated cell	16 studies	32% ± 11%	Explore
basal cell	14 studies	29% ± 15%	Explore
myofibroblast cell	14 studies	52% ± 26%	Explore
connective tissue cell	14 studies	61% ± 24%	Explore
epithelial cell	12 studies	46% ± 21%	Explore
endothelial cell of lymphatic vessel	11 studies	31% ± 13%	Explore
capillary endothelial cell	10 studies	37% ± 23%	Explore
endothelial cell of artery	10 studies	37% ± 23%	Explore
mast cell	9 studies	23% ± 13%	Explore
natural killer cell	9 studies	20% ± 5%	Explore
secretory cell	8 studies	34% ± 9%	Explore
abnormal cell	8 studies	35% ± 13%	Explore
vein endothelial cell	8 studies	38% ± 26%	Explore
club cell	7 studies	29% ± 7%	Explore
platelet	7 studies	27% ± 8%	Explore
endothelial cell of vascular tree	7 studies	28% ± 8%	Explore
neuron	7 studies	53% ± 28%	Explore
gamma-delta T cell	7 studies	23% ± 13%	Explore
CD8-positive, alpha-beta memory T cell	6 studies	19% ± 3%	Explore
respiratory goblet cell	6 studies	31% ± 17%	Explore
kidney loop of Henle epithelial cell	6 studies	28% ± 8%	Explore
mesothelial cell	6 studies	63% ± 17%	Explore
CD8-positive, alpha-beta T cell	6 studies	22% ± 8%	Explore
astrocyte	6 studies	30% ± 16%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	5 studies	19% ± 4%	Explore
CD16-negative, CD56-bright natural killer cell, human	5 studies	23% ± 7%	Explore
CD4-positive, alpha-beta T cell	5 studies	22% ± 10%	Explore
effector memory CD8-positive, alpha-beta T cell	5 studies	17% ± 3%	Explore
progenitor cell	5 studies	54% ± 25%	Explore
renal alpha-intercalated cell	5 studies	52% ± 21%	Explore
enteroendocrine cell	5 studies	43% ± 24%	Explore
type I pneumocyte	5 studies	31% ± 17%	Explore
hematopoietic stem cell	5 studies	26% ± 4%	Explore
goblet cell	5 studies	35% ± 15%	Explore
ionocyte	4 studies	31% ± 9%	Explore
pancreatic A cell	4 studies	46% ± 18%	Explore
CD16-positive, CD56-dim natural killer cell, human	4 studies	19% ± 2%	Explore
mature NK T cell	4 studies	17% ± 1%	Explore
kidney distal convoluted tubule epithelial cell	4 studies	55% ± 12%	Explore
epithelial cell of proximal tubule	4 studies	28% ± 15%	Explore
retinal ganglion cell	4 studies	70% ± 19%	Explore
plasma cell	4 studies	30% ± 9%	Explore
retina horizontal cell	4 studies	36% ± 19%	Explore
luminal hormone-sensing cell of mammary gland	4 studies	64% ± 16%	Explore
GABAergic neuron	4 studies	28% ± 6%	Explore
oligodendrocyte precursor cell	4 studies	35% ± 15%	Explore
hematopoietic precursor cell	3 studies	34% ± 11%	Explore
duct epithelial cell	3 studies	22% ± 8%	Explore
type B pancreatic cell	3 studies	48% ± 13%	Explore
non-classical monocyte	3 studies	30% ± 7%	Explore
glomerular endothelial cell	3 studies	29% ± 8%	Explore
T cell	3 studies	41% ± 19%	Explore
neural crest cell	3 studies	48% ± 5%	Explore
retinal bipolar neuron	3 studies	30% ± 13%	Explore
type II pneumocyte	3 studies	32% ± 17%	Explore
Mueller cell	3 studies	31% ± 7%	Explore
regulatory T cell	3 studies	23% ± 11%	Explore
macrophage	3 studies	20% ± 6%	Explore
myoepithelial cell	3 studies	45% ± 16%	Explore
luminal cell of prostate epithelium	3 studies	18% ± 4%	Explore
glutamatergic neuron	3 studies	37% ± 10%	Explore
pancreatic ductal cell	3 studies	48% ± 17%	Explore
megakaryocyte	3 studies	57% ± 9%	Explore
megakaryocyte-erythroid progenitor cell	3 studies	45% ± 11%	Explore
glial cell	3 studies	43% ± 30%	Explore
group 3 innate lymphoid cell	3 studies	23% ± 10%	Explore
interneuron	3 studies	23% ± 9%	Explore

II. Expression across tissues

sc-RNAseq dataData table

Name	Number of supported studies	Average coverage
lung	10 studies	35% ± 20%	Explore
kidney	8 studies	26% ± 15%	Explore
eye	8 studies	23% ± 10%	Explore
intestine	5 studies	47% ± 20%	Explore
brain	5 studies	22% ± 4%	Explore
uterus	4 studies	36% ± 7%	Explore
breast	4 studies	26% ± 7%	Explore
pancreas	3 studies	49% ± 8%	Explore

Bulk RNAseq dataData table

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
prostate	100%	14915.97	245 / 245	100%	525.16	500 / 502
brain	100%	7773.20	2630 / 2642	100%	317.98	704 / 705
breast	100%	15259.55	459 / 459	99%	1006.44	1111 / 1118
skin	100%	7601.15	1805 / 1809	100%	504.57	470 / 472
thymus	100%	12840.01	653 / 653	99%	341.92	601 / 605
kidney	100%	12093.92	89 / 89	99%	253.61	893 / 901
ovary	100%	21418.44	180 / 180	99%	277.33	426 / 430
adrenal gland	100%	9739.16	258 / 258	98%	444.48	226 / 230
bladder	100%	11257.67	21 / 21	95%	188.70	478 / 504
pancreas	94%	3449.06	308 / 328	99%	206.14	176 / 178
lung	100%	9103.11	577 / 578	92%	175.32	1066 / 1155
uterus	100%	13652.51	170 / 170	91%	258.83	416 / 459
intestine	100%	8581.72	965 / 966	90%	154.09	472 / 527
stomach	100%	6484.99	358 / 359	82%	134.04	234 / 286
esophagus	100%	7728.58	1442 / 1445	63%	71.59	116 / 183
liver	66%	1884.46	149 / 226	82%	120.99	333 / 406
adipose	100%	8148.33	1204 / 1204	0%	0	0 / 0
blood vessel	100%	19170.29	1335 / 1335	0%	0	0 / 0
eye	0%	0	0 / 0	100%	306.10	80 / 80
spleen	100%	6296.97	241 / 241	0%	0	0 / 0
heart	96%	6865.45	828 / 861	0%	0	0 / 0
muscle	96%	5118.14	770 / 803	0%	0	0 / 0
tonsil	0%	0	0 / 0	89%	124.83	40 / 45
lymph node	0%	0	0 / 0	86%	94.38	25 / 29
peripheral blood	64%	2145.49	596 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1