LYZ report

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I. Expression across cell types

Cell ontologyData table

Name	Number of supported studies	Average coverage
macrophage	45 studies	61% ± 25%	Explore
conventional dendritic cell	32 studies	84% ± 15%	Explore
dendritic cell	29 studies	70% ± 19%	Explore
monocyte	29 studies	80% ± 19%	Explore
classical monocyte	29 studies	95% ± 6%	Explore
non-classical monocyte	27 studies	77% ± 24%	Explore
neutrophil	15 studies	54% ± 30%	Explore
myeloid cell	13 studies	68% ± 26%	Explore
natural killer cell	9 studies	31% ± 12%	Explore
CD16-negative, CD56-bright natural killer cell, human	9 studies	32% ± 11%	Explore
alveolar macrophage	8 studies	73% ± 29%	Explore
plasmacytoid dendritic cell	8 studies	35% ± 22%	Explore
mononuclear phagocyte	8 studies	68% ± 26%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	8 studies	32% ± 11%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	8 studies	30% ± 11%	Explore
B cell	7 studies	26% ± 5%	Explore
platelet	7 studies	49% ± 30%	Explore
naive B cell	7 studies	34% ± 14%	Explore
CD16-positive, CD56-dim natural killer cell, human	7 studies	31% ± 12%	Explore
gamma-delta T cell	7 studies	35% ± 13%	Explore
leukocyte	6 studies	41% ± 14%	Explore
intermediate monocyte	6 studies	88% ± 13%	Explore
memory B cell	6 studies	30% ± 10%	Explore
mucosal invariant T cell	6 studies	28% ± 7%	Explore
T cell	5 studies	32% ± 10%	Explore
monocyte-derived dendritic cell	5 studies	82% ± 13%	Explore
plasma cell	5 studies	30% ± 26%	Explore
inflammatory macrophage	5 studies	68% ± 22%	Explore
CD4-positive, alpha-beta memory T cell	5 studies	30% ± 12%	Explore
mature NK T cell	5 studies	23% ± 5%	Explore
effector memory CD8-positive, alpha-beta T cell	5 studies	36% ± 12%	Explore
deuterosomal cell	4 studies	38% ± 7%	Explore
respiratory goblet cell	4 studies	17% ± 2%	Explore
CD4-positive, alpha-beta T cell	4 studies	26% ± 11%	Explore
plasmablast	4 studies	42% ± 22%	Explore
goblet cell	4 studies	37% ± 19%	Explore
paneth cell	4 studies	86% ± 19%	Explore
mucus secreting cell	4 studies	39% ± 26%	Explore
hematopoietic precursor cell	4 studies	53% ± 20%	Explore
CD8-positive, alpha-beta memory T cell	4 studies	34% ± 13%	Explore
regulatory T cell	4 studies	35% ± 9%	Explore
central memory CD8-positive, alpha-beta T cell	4 studies	31% ± 5%	Explore
hematopoietic stem cell	4 studies	26% ± 15%	Explore
erythrocyte	4 studies	37% ± 23%	Explore
CD8-positive, alpha-beta T cell	3 studies	29% ± 5%	Explore
endothelial cell	3 studies	26% ± 11%	Explore
common myeloid progenitor	3 studies	45% ± 18%	Explore
epithelial cell	3 studies	23% ± 1%	Explore
tissue-resident macrophage	3 studies	56% ± 23%	Explore
brush cell	3 studies	40% ± 23%	Explore
fibroblast	3 studies	31% ± 3%	Explore
granulocyte	3 studies	52% ± 21%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	3 studies	30% ± 1%	Explore
central memory CD4-positive, alpha-beta T cell	3 studies	26% ± 5%	Explore
double negative thymocyte	3 studies	39% ± 12%	Explore

II. Expression across tissues

sc-RNAseq dataData table

Name	Number of supported studies	Average coverage
peripheral blood	19 studies	43% ± 15%	Explore
lung	13 studies	28% ± 11%	Explore
bone marrow	4 studies	38% ± 16%	Explore
liver	4 studies	32% ± 9%	Explore
intestine	3 studies	22% ± 6%	Explore

Bulk RNAseq dataData table

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
lung	98%	11257.68	568 / 578	84%	680.25	965 / 1155
stomach	84%	11810.62	303 / 359	83%	1556.85	236 / 286
intestine	58%	3152.69	564 / 966	86%	1144.95	452 / 527
pancreas	43%	1228.10	141 / 328	88%	1333.65	156 / 178
breast	44%	693.13	203 / 459	56%	223.74	629 / 1118
spleen	97%	7275.02	234 / 241	0%	0	0 / 0
peripheral blood	86%	60560.67	800 / 929	0%	0	0 / 0
esophagus	24%	497.56	347 / 1445	60%	1198.74	110 / 183
lymph node	0%	0	0 / 0	83%	1489.61	24 / 29
bladder	33%	504.19	7 / 21	47%	297.87	235 / 504
adipose	77%	1985.11	927 / 1204	0%	0	0 / 0
kidney	12%	202.64	11 / 89	57%	187.52	514 / 901
liver	18%	228.83	41 / 226	50%	342.71	201 / 406
tonsil	0%	0	0 / 0	64%	324.67	29 / 45
thymus	21%	358.36	138 / 653	42%	102.87	256 / 605
skin	7%	82.88	129 / 1809	49%	177.51	231 / 472
uterus	16%	293.89	28 / 170	33%	120.16	151 / 459
blood vessel	49%	1046.21	657 / 1335	0%	0	0 / 0
prostate	18%	277.12	45 / 245	24%	44.73	118 / 502
ovary	12%	155.38	21 / 180	29%	61.78	125 / 430
adrenal gland	30%	608.01	77 / 258	2%	2.19	4 / 230
heart	17%	219.08	150 / 861	0%	0	0 / 0
brain	2%	23.86	44 / 2642	9%	20.03	66 / 705
eye	0%	0	0 / 0	9%	15.95	7 / 80
muscle	2%	53.43	14 / 803	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1