Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| endothelial cell | 20 studies | 32% ± 14% | |
| oligodendrocyte | 14 studies | 47% ± 17% | |
| astrocyte | 14 studies | 39% ± 18% | |
| ciliated cell | 12 studies | 26% ± 8% | |
| microglial cell | 12 studies | 47% ± 12% | |
| glutamatergic neuron | 11 studies | 54% ± 22% | |
| macrophage | 11 studies | 38% ± 16% | |
| oligodendrocyte precursor cell | 11 studies | 45% ± 16% | |
| GABAergic neuron | 9 studies | 54% ± 20% | |
| fibroblast | 9 studies | 28% ± 7% | |
| natural killer cell | 8 studies | 21% ± 6% | |
| B cell | 8 studies | 26% ± 7% | |
| neuron | 8 studies | 42% ± 22% | |
| epithelial cell | 8 studies | 37% ± 16% | |
| basal cell | 8 studies | 31% ± 13% | |
| adipocyte | 8 studies | 23% ± 6% | |
| pericyte | 7 studies | 32% ± 12% | |
| myeloid cell | 7 studies | 31% ± 10% | |
| retinal cone cell | 7 studies | 35% ± 15% | |
| retinal rod cell | 7 studies | 31% ± 13% | |
| dendritic cell | 7 studies | 36% ± 15% | |
| naive B cell | 6 studies | 18% ± 3% | |
| interneuron | 6 studies | 60% ± 20% | |
| club cell | 6 studies | 30% ± 10% | |
| retina horizontal cell | 6 studies | 33% ± 15% | |
| CD8-positive, alpha-beta T cell | 6 studies | 19% ± 3% | |
| mast cell | 6 studies | 24% ± 9% | |
| classical monocyte | 5 studies | 26% ± 10% | |
| non-classical monocyte | 5 studies | 28% ± 12% | |
| CD16-positive, CD56-dim natural killer cell, human | 5 studies | 20% ± 3% | |
| CD4-positive, alpha-beta T cell | 5 studies | 20% ± 1% | |
| amacrine cell | 5 studies | 28% ± 10% | |
| cardiac muscle cell | 5 studies | 32% ± 8% | |
| respiratory goblet cell | 5 studies | 36% ± 10% | |
| endothelial cell of lymphatic vessel | 5 studies | 29% ± 6% | |
| monocyte | 5 studies | 33% ± 8% | |
| smooth muscle cell | 5 studies | 27% ± 3% | |
| type I pneumocyte | 5 studies | 24% ± 7% | |
| type II pneumocyte | 5 studies | 22% ± 7% | |
| CD16-negative, CD56-bright natural killer cell, human | 4 studies | 19% ± 2% | |
| effector memory CD8-positive, alpha-beta T cell | 4 studies | 22% ± 1% | |
| granule cell | 4 studies | 38% ± 5% | |
| retinal bipolar neuron | 4 studies | 28% ± 12% | |
| retinal ganglion cell | 4 studies | 44% ± 21% | |
| lymphocyte | 4 studies | 32% ± 12% | |
| T cell | 4 studies | 24% ± 6% | |
| goblet cell | 4 studies | 37% ± 32% | |
| naive thymus-derived CD4-positive, alpha-beta T cell | 3 studies | 19% ± 2% | |
| GABAergic interneuron | 3 studies | 51% ± 5% | |
| glial cell | 3 studies | 25% ± 10% | |
| progenitor cell | 3 studies | 37% ± 8% | |
| plasma cell | 3 studies | 23% ± 2% | |
| squamous epithelial cell | 3 studies | 47% ± 20% | |
| brush cell | 3 studies | 29% ± 4% | |
| mononuclear phagocyte | 3 studies | 27% ± 10% | |
| mucosal invariant T cell | 3 studies | 19% ± 2% | |
| GABAergic amacrine cell | 3 studies | 35% ± 11% | |
| OFF-bipolar cell | 3 studies | 38% ± 15% | |
| ON-bipolar cell | 3 studies | 39% ± 14% | |
| glycinergic amacrine cell | 3 studies | 33% ± 5% | |
| rod bipolar cell | 3 studies | 34% ± 17% | |
| hepatocyte | 3 studies | 54% ± 21% | |
| ependymal cell | 3 studies | 32% ± 17% | |
| enterocyte | 3 studies | 19% ± 3% | |
| enteroendocrine cell | 3 studies | 24% ± 7% | |
| alveolar macrophage | 3 studies | 38% ± 13% | |
| CD8-positive, alpha-beta memory T cell | 3 studies | 17% ± 1% | |
| mesothelial cell | 3 studies | 29% ± 3% | |
| mural cell | 3 studies | 35% ± 12% | |
| mucus secreting cell | 3 studies | 30% ± 6% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| brain | 16 studies | 47% ± 21% | |
| lung | 8 studies | 24% ± 8% | |
| eye | 7 studies | 35% ± 14% | |
| heart | 4 studies | 26% ± 5% | |
| peripheral blood | 3 studies | 29% ± 3% | |
| liver | 3 studies | 36% ± 17% | |
| intestine | 3 studies | 19% ± 1% | |
| adipose | 3 studies | 29% ± 3% | |
| kidney | 3 studies | 25% ± 6% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| bladder | 100% | 2638.81 | 21 / 21 | 100% | 6.81 | 504 / 504 |
| esophagus | 100% | 2570.96 | 1445 / 1445 | 100% | 12.69 | 183 / 183 |
| prostate | 100% | 2494.72 | 245 / 245 | 100% | 6.17 | 502 / 502 |
| lung | 100% | 2688.16 | 578 / 578 | 100% | 6.55 | 1154 / 1155 |
| breast | 100% | 2193.37 | 459 / 459 | 100% | 7.28 | 1114 / 1118 |
| intestine | 100% | 3188.92 | 966 / 966 | 100% | 7.41 | 525 / 527 |
| thymus | 100% | 2618.07 | 653 / 653 | 100% | 4.79 | 602 / 605 |
| pancreas | 100% | 2305.52 | 328 / 328 | 99% | 5.79 | 177 / 178 |
| uterus | 100% | 2479.25 | 170 / 170 | 99% | 5.30 | 456 / 459 |
| ovary | 100% | 2743.75 | 180 / 180 | 99% | 4.67 | 427 / 430 |
| stomach | 100% | 2052.75 | 359 / 359 | 99% | 9.38 | 284 / 286 |
| kidney | 100% | 1930.89 | 89 / 89 | 97% | 3.87 | 871 / 901 |
| brain | 99% | 1656.28 | 2622 / 2642 | 97% | 3.13 | 686 / 705 |
| skin | 100% | 1965.53 | 1809 / 1809 | 93% | 3.12 | 441 / 472 |
| adrenal gland | 100% | 1585.67 | 258 / 258 | 92% | 2.89 | 211 / 230 |
| liver | 100% | 1406.62 | 226 / 226 | 86% | 2.44 | 350 / 406 |
| adipose | 100% | 2008.24 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 3.69 | 29 / 29 |
| spleen | 100% | 2946.61 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 6.14 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 4.59 | 1 / 1 |
| blood vessel | 100% | 1851.07 | 1334 / 1335 | 0% | 0 | 0 / 0 |
| muscle | 100% | 1642.31 | 801 / 803 | 0% | 0 | 0 / 0 |
| heart | 97% | 1230.53 | 838 / 861 | 0% | 0 | 0 / 0 |
| peripheral blood | 97% | 2014.99 | 899 / 929 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 73% | 1.49 | 58 / 80 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0071392 | Biological process | cellular response to estradiol stimulus |
| GO_0000122 | Biological process | negative regulation of transcription by RNA polymerase II |
| GO_0006357 | Biological process | regulation of transcription by RNA polymerase II |
| GO_0005654 | Cellular component | nucleoplasm |
| GO_0005634 | Cellular component | nucleus |
| GO_0003677 | Molecular function | DNA binding |
| GO_0042826 | Molecular function | histone deacetylase binding |
| GO_0003714 | Molecular function | transcription corepressor activity |
| GO_0001222 | Molecular function | transcription corepressor binding |
| GO_0005515 | Molecular function | protein binding |
| GO_1990226 | Molecular function | histone methyltransferase binding |
| GO_1990381 | Molecular function | ubiquitin-specific protease binding |
| GO_0030331 | Molecular function | nuclear estrogen receptor binding |
| Gene name | LCOR |
| Protein name | LCOR protein Ligand-dependent corepressor (LCoR) (Mblk1-related protein 2) Ligand dependent nuclear receptor corepressor |
| Synonyms | MLR2 KIAA1795 C10orf12 |
| Description | FUNCTION: May act as transcription activator that binds DNA elements with the sequence 5'-CCCTATCGATCGATCTCTACCT-3' (By similarity). Repressor of ligand-dependent transcription activation by target nuclear receptors. Repressor of ligand-dependent transcription activation by ESR1, ESR2, NR3C1, PGR, RARA, RARB, RARG, RXRA and VDR. . |
| Accessions | A0A6Q8PGV7 ENST00000674725.1 A0A6Q8PFV7 Q96JN0 ENST00000674796.1 A0A6Q8PGL8 A0A6Q8PGR8 ENST00000676314.1 A0A6Q8PFF1 A0A6Q8PGP3 ENST00000676123.1 ENST00000675151.1 ENST00000421806.4 [Q96JN0-3] A0A6Q8PGQ5 ENST00000675251.1 A0A6Q8PFM6 ENST00000675902.1 ENST00000676414.1 ENST00000676381.1 A0A6Q8PH28 A0A6Q8PG71 ENST00000675471.1 [Q96JN0-1] ENST00000371097.8 [Q96JN0-1] A0A6Q8PG56 ENST00000675915.1 ENST00000675125.1 ENST00000676187.1 A0A6Q8PGD6 ENST00000371103.8 [Q96JN0-1] ENST00000675537.1 [Q96JN0-1] A0A6Q8PHQ4 ENST00000676257.1 ENST00000675117.1 A0A6Q8PFQ9 ENST00000675250.1 ENST00000676067.1 A0A6Q8PFM9 ENST00000540664.6 [Q96JN0-2] ENST00000675971.1 [Q96JN0-1] ENST00000356016.7 [Q96JN0-1] A0A6Q8PG83 A2VCT1 ENST00000675687.1 |