JPT1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0005829Cellular componentcytosol
GO_0015630Cellular componentmicrotubule cytoskeleton
GO_0045171Cellular componentintercellular bridge
GO_0005634Cellular componentnucleus
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameJPT1
Protein nameJupiter microtubule associated homolog 1
Jupiter microtubule associated homolog 1 (Androgen-regulated protein 2) (Hematological and neurological expressed 1 protein) [Cleaved into: Jupiter microtubule associated homolog 1, N-terminally processed]
SynonymsARM2
HN1
DescriptionFUNCTION: Modulates negatively AKT-mediated GSK3B signaling . Induces CTNNB1 'Ser-33' phosphorylation and degradation through the suppression of the inhibitory 'Ser-9' phosphorylation of GSK3B, which represses the function of the APC:CTNNB1:GSK3B complex and the interaction with CDH1/E-cadherin in adherent junctions . Plays a role in the regulation of cell cycle and cell adhesion . Has an inhibitory role on AR-signaling pathway through the induction of receptor proteasomal degradation . .

AccessionsENST00000581874.1
ENST00000482348.5 [Q9UK76-3]
ENST00000304834.11
ENST00000580380.1
J3KSH8
J3KT51
ENST00000409753.8 [Q9UK76-1]
ENST00000481647.5 [Q9UK76-3]
ENST00000470924.5 [Q9UK76-3]
F2Z3M5
Q9UK76
ENST00000356033.8 [Q9UK76-2]
ENST00000476258.5 [Q9UK76-3]