JAZF1 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
microglial cell	15 studies	58% ± 16%	Explore
endothelial cell	15 studies	30% ± 11%	Explore
B cell	15 studies	29% ± 14%	Explore
natural killer cell	14 studies	28% ± 15%	Explore
oligodendrocyte precursor cell	14 studies	50% ± 17%	Explore
oligodendrocyte	14 studies	39% ± 14%	Explore
glutamatergic neuron	13 studies	57% ± 25%	Explore
CD16-positive, CD56-dim natural killer cell, human	13 studies	24% ± 9%	Explore
astrocyte	12 studies	32% ± 13%	Explore
macrophage	12 studies	33% ± 12%	Explore
GABAergic neuron	11 studies	54% ± 23%	Explore
naive B cell	11 studies	20% ± 3%	Explore
fibroblast	11 studies	24% ± 5%	Explore
smooth muscle cell	9 studies	26% ± 7%	Explore
adipocyte	8 studies	23% ± 5%	Explore
interneuron	7 studies	48% ± 25%	Explore
dendritic cell	7 studies	36% ± 14%	Explore
mast cell	7 studies	28% ± 10%	Explore
non-classical monocyte	6 studies	25% ± 10%	Explore
neuron	6 studies	41% ± 15%	Explore
myeloid cell	6 studies	31% ± 11%	Explore
ciliated cell	6 studies	40% ± 18%	Explore
T cell	6 studies	28% ± 6%	Explore
pericyte	6 studies	25% ± 5%	Explore
erythrocyte	5 studies	30% ± 18%	Explore
epithelial cell	5 studies	30% ± 8%	Explore
cardiac muscle cell	5 studies	54% ± 15%	Explore
endothelial cell of lymphatic vessel	5 studies	19% ± 2%	Explore
monocyte	5 studies	45% ± 6%	Explore
type I pneumocyte	5 studies	33% ± 5%	Explore
mature NK T cell	5 studies	21% ± 8%	Explore
granule cell	4 studies	44% ± 14%	Explore
CD8-positive, alpha-beta T cell	4 studies	25% ± 8%	Explore
lymphocyte	4 studies	39% ± 10%	Explore
amacrine cell	4 studies	19% ± 3%	Explore
retina horizontal cell	4 studies	45% ± 15%	Explore
retinal ganglion cell	4 studies	42% ± 20%	Explore
retinal rod cell	4 studies	39% ± 22%	Explore
classical monocyte	3 studies	23% ± 1%	Explore
conventional dendritic cell	3 studies	25% ± 7%	Explore
GABAergic interneuron	3 studies	59% ± 1%	Explore
differentiation-committed oligodendrocyte precursor	3 studies	43% ± 14%	Explore
CD16-negative, CD56-bright natural killer cell, human	3 studies	29% ± 7%	Explore
CD4-positive, alpha-beta T cell	3 studies	23% ± 3%	Explore
mesothelial cell	3 studies	35% ± 13%	Explore
GABAergic amacrine cell	3 studies	35% ± 8%	Explore
OFF-bipolar cell	3 studies	25% ± 5%	Explore
retinal cone cell	3 studies	26% ± 6%	Explore
cholangiocyte	3 studies	53% ± 14%	Explore
hepatocyte	3 studies	43% ± 18%	Explore
ependymal cell	3 studies	37% ± 13%	Explore
connective tissue cell	3 studies	17% ± 0%	Explore
alveolar macrophage	3 studies	40% ± 8%	Explore
type II pneumocyte	3 studies	18% ± 3%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	3 studies	23% ± 6%	Explore
gamma-delta T cell	3 studies	19% ± 1%	Explore
memory B cell	3 studies	18% ± 2%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
brain	18 studies	45% ± 21%	Explore
eye	5 studies	29% ± 8%	Explore
heart	4 studies	35% ± 8%	Explore
lung	4 studies	25% ± 5%	Explore
liver	3 studies	21% ± 4%	Explore
adipose	3 studies	33% ± 6%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
adrenal gland	100%	5577.27	258 / 258	100%	56.92	230 / 230
thymus	99%	1203.74	649 / 653	100%	19.39	605 / 605
breast	100%	1535.87	459 / 459	97%	10.79	1089 / 1118
ovary	100%	1554.02	180 / 180	96%	9.69	414 / 430
brain	95%	1832.51	2518 / 2642	100%	25.52	705 / 705
prostate	99%	2361.64	243 / 245	96%	12.64	481 / 502
skin	97%	1041.07	1758 / 1809	97%	23.35	456 / 472
lung	99%	1296.76	573 / 578	92%	8.33	1060 / 1155
uterus	100%	4479.01	170 / 170	90%	10.13	411 / 459
kidney	80%	507.43	71 / 89	97%	14.86	871 / 901
esophagus	87%	1845.71	1252 / 1445	87%	8.33	159 / 183
liver	73%	439.42	164 / 226	93%	11.69	378 / 406
bladder	100%	2467.95	21 / 21	65%	5.21	328 / 504
intestine	92%	2716.06	887 / 966	60%	4.37	316 / 527
pancreas	56%	305.77	183 / 328	96%	13.83	170 / 178
stomach	75%	822.97	268 / 359	73%	6.07	210 / 286
blood vessel	100%	2892.98	1335 / 1335	0%	0	0 / 0
spleen	100%	1420.69	241 / 241	0%	0	0 / 0
adipose	100%	1847.91	1202 / 1204	0%	0	0 / 0
lymph node	0%	0	0 / 0	97%	16.62	28 / 29
heart	94%	1018.90	808 / 861	0%	0	0 / 0
tonsil	0%	0	0 / 0	93%	8.49	42 / 45
eye	0%	0	0 / 0	91%	15.94	73 / 80
peripheral blood	81%	1478.94	755 / 929	0%	0	0 / 0
muscle	64%	395.67	516 / 803	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

III. Associated gene sets

GO_0006629	Biological process	lipid metabolic process
GO_0000122	Biological process	negative regulation of transcription by RNA polymerase II
GO_0005654	Cellular component	nucleoplasm
GO_0005829	Cellular component	cytosol
GO_0017053	Cellular component	transcription repressor complex
GO_0001650	Cellular component	fibrillar center
GO_0005634	Cellular component	nucleus
GO_0003714	Molecular function	transcription corepressor activity
GO_0005515	Molecular function	protein binding
GO_0046872	Molecular function	metal ion binding

IV. Literature review

[source]

Gene name	JAZF1
Protein name	JAZF zinc finger 1 Juxtaposed with another zinc finger protein 1 (TAK1-interacting protein 27) (Zinc finger protein 802)
Synonyms	ZNF802 TIP27
Description	FUNCTION: Acts as a transcriptional corepressor of orphan nuclear receptor NR2C2 . Inhibits expression of the gluconeogenesis enzyme PCK2 through inhibition of NR2C2 activity (By similarity). Also involved in transcriptional activation of NAMPT by promoting expression of PPARA and PPARD (By similarity). Plays a role in lipid metabolism by suppressing lipogenesis, increasing lipolysis and decreasing lipid accumulation in adipose tissue (By similarity). Plays a role in glucose homeostasis by improving glucose metabolism and insulin sensitivity (By similarity). .
Accessions	ENST00000649905.1 ENST00000283928.10 [Q86VZ6-1] A0A3B3ISK8 F8WD35 ENST00000447620.5 C9JGY8 Q86VZ6 ENST00000430432.5 H0Y403 ENST00000452993.5 ENST00000427814.5 C9JWY1

JAZF1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review