H1-3 report

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I. Expression across cell types

Cell ontologyData table

Name	Number of supported studies	Average coverage
B cell	14 studies	26% ± 13%	Explore
natural killer cell	14 studies	36% ± 16%	Explore
CD4-positive, alpha-beta T cell	14 studies	27% ± 9%	Explore
CD8-positive, alpha-beta T cell	13 studies	26% ± 8%	Explore
T cell	10 studies	30% ± 16%	Explore
plasmacytoid dendritic cell	10 studies	30% ± 14%	Explore
CD16-negative, CD56-bright natural killer cell, human	9 studies	29% ± 9%	Explore
CD16-positive, CD56-dim natural killer cell, human	9 studies	29% ± 10%	Explore
regulatory T cell	9 studies	26% ± 8%	Explore
plasmablast	8 studies	42% ± 20%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	8 studies	28% ± 7%	Explore
conventional dendritic cell	8 studies	27% ± 15%	Explore
mucosal invariant T cell	8 studies	23% ± 7%	Explore
gamma-delta T cell	8 studies	31% ± 14%	Explore
effector CD8-positive, alpha-beta T cell	7 studies	34% ± 16%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	6 studies	28% ± 8%	Explore
classical monocyte	6 studies	23% ± 13%	Explore
CD8-positive, alpha-beta memory T cell	6 studies	31% ± 6%	Explore
dendritic cell	5 studies	34% ± 8%	Explore
mature NK T cell	5 studies	29% ± 8%	Explore
precursor B cell	5 studies	33% ± 8%	Explore
memory B cell	5 studies	23% ± 5%	Explore
CD4-positive, alpha-beta memory T cell	5 studies	24% ± 9%	Explore
monocyte	4 studies	22% ± 8%	Explore
plasma cell	4 studies	36% ± 9%	Explore
hematopoietic precursor cell	4 studies	40% ± 18%	Explore
effector memory CD8-positive, alpha-beta T cell	4 studies	35% ± 9%	Explore
pro-B cell	4 studies	35% ± 8%	Explore
effector memory CD4-positive, alpha-beta T cell	4 studies	25% ± 7%	Explore
erythrocyte	4 studies	38% ± 16%	Explore
naive B cell	4 studies	28% ± 8%	Explore
macrophage	3 studies	23% ± 6%	Explore
mast cell	3 studies	41% ± 14%	Explore
leukocyte	3 studies	20% ± 2%	Explore
effector CD4-positive, alpha-beta T cell	3 studies	34% ± 11%	Explore
granulocyte monocyte progenitor cell	3 studies	27% ± 9%	Explore
hematopoietic stem cell	3 studies	58% ± 8%	Explore
central memory CD8-positive, alpha-beta T cell	3 studies	29% ± 6%	Explore
double negative thymocyte	3 studies	34% ± 10%	Explore

II. Expression across tissues

sc-RNAseq dataData table

Name	Number of supported studies	Average coverage
peripheral blood	10 studies	27% ± 12%	Explore

Bulk RNAseq dataData table

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
breast	72%	35.01	329 / 459	57%	6.44	636 / 1118
prostate	83%	44.61	203 / 245	40%	1.23	200 / 502
ovary	38%	9.54	69 / 180	81%	4.78	348 / 430
lung	66%	35.40	382 / 578	48%	5.92	549 / 1155
esophagus	35%	8.54	504 / 1445	73%	3.22	133 / 183
intestine	67%	40.81	651 / 966	34%	5.68	178 / 527
bladder	48%	6.67	10 / 21	45%	12.32	225 / 504
uterus	32%	8.76	54 / 170	58%	4.43	266 / 459
thymus	58%	17.96	378 / 653	31%	1.30	187 / 605
stomach	34%	11.25	122 / 359	44%	5.09	125 / 286
spleen	74%	35.81	179 / 241	0%	0	0 / 0
peripheral blood	67%	111.50	621 / 929	0%	0	0 / 0
skin	50%	28.03	911 / 1809	14%	0.31	67 / 472
lymph node	0%	0	0 / 0	62%	2.54	18 / 29
kidney	51%	11.33	45 / 89	9%	1.07	79 / 901
adipose	58%	21.14	702 / 1204	0%	0	0 / 0
tonsil	0%	0	0 / 0	44%	0.85	20 / 45
blood vessel	39%	13.35	517 / 1335	0%	0	0 / 0
pancreas	2%	0.19	7 / 328	26%	1.04	47 / 178
adrenal gland	17%	2.36	45 / 258	6%	0.14	14 / 230
heart	23%	4.58	198 / 861	0%	0	0 / 0
brain	12%	3.54	318 / 2642	10%	0.55	68 / 705
liver	15%	4.67	34 / 226	3%	0.07	13 / 406
muscle	2%	0.22	18 / 803	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
eye	0%	0	0 / 0	0%	0	0 / 80
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1