Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 51 studies | 54% ± 22% | |
fibroblast | 45 studies | 64% ± 22% | |
macrophage | 40 studies | 42% ± 16% | |
pericyte | 37 studies | 57% ± 23% | |
smooth muscle cell | 33 studies | 53% ± 21% | |
conventional dendritic cell | 29 studies | 50% ± 15% | |
dendritic cell | 26 studies | 54% ± 23% | |
endothelial cell of lymphatic vessel | 20 studies | 37% ± 15% | |
astrocyte | 19 studies | 48% ± 20% | |
plasmacytoid dendritic cell | 18 studies | 45% ± 13% | |
basal cell | 18 studies | 47% ± 21% | |
ciliated cell | 18 studies | 49% ± 20% | |
connective tissue cell | 18 studies | 58% ± 23% | |
endothelial cell of artery | 17 studies | 63% ± 19% | |
oligodendrocyte | 17 studies | 57% ± 17% | |
classical monocyte | 17 studies | 26% ± 12% | |
capillary endothelial cell | 17 studies | 60% ± 21% | |
microglial cell | 16 studies | 41% ± 17% | |
monocyte | 15 studies | 34% ± 17% | |
natural killer cell | 15 studies | 22% ± 8% | |
epithelial cell | 15 studies | 41% ± 21% | |
vein endothelial cell | 15 studies | 57% ± 20% | |
endothelial cell of vascular tree | 15 studies | 66% ± 16% | |
myeloid cell | 15 studies | 45% ± 13% | |
myofibroblast cell | 13 studies | 56% ± 22% | |
goblet cell | 12 studies | 55% ± 19% | |
mast cell | 12 studies | 24% ± 8% | |
type I pneumocyte | 11 studies | 38% ± 13% | |
adipocyte | 11 studies | 54% ± 19% | |
secretory cell | 10 studies | 58% ± 25% | |
CD16-negative, CD56-bright natural killer cell, human | 9 studies | 29% ± 8% | |
alveolar macrophage | 8 studies | 52% ± 15% | |
club cell | 8 studies | 55% ± 22% | |
non-classical monocyte | 8 studies | 25% ± 13% | |
leukocyte | 8 studies | 25% ± 7% | |
glial cell | 8 studies | 42% ± 14% | |
ionocyte | 7 studies | 68% ± 23% | |
respiratory goblet cell | 7 studies | 62% ± 21% | |
mononuclear phagocyte | 7 studies | 41% ± 17% | |
oligodendrocyte precursor cell | 7 studies | 29% ± 11% | |
mesothelial cell | 7 studies | 30% ± 14% | |
platelet | 7 studies | 36% ± 15% | |
CD16-positive, CD56-dim natural killer cell, human | 7 studies | 22% ± 6% | |
T cell | 6 studies | 27% ± 6% | |
innate lymphoid cell | 6 studies | 25% ± 3% | |
brush cell | 6 studies | 54% ± 13% | |
monocyte-derived dendritic cell | 5 studies | 57% ± 25% | |
megakaryocyte | 5 studies | 74% ± 15% | |
abnormal cell | 5 studies | 23% ± 4% | |
Schwann cell | 5 studies | 61% ± 20% | |
adventitial cell | 5 studies | 77% ± 26% | |
mucus secreting cell | 5 studies | 27% ± 5% | |
hematopoietic stem cell | 5 studies | 25% ± 10% | |
deuterosomal cell | 4 studies | 43% ± 15% | |
duct epithelial cell | 4 studies | 40% ± 15% | |
neutrophil | 4 studies | 23% ± 4% | |
squamous epithelial cell | 4 studies | 50% ± 21% | |
type B pancreatic cell | 4 studies | 53% ± 15% | |
GABAergic neuron | 4 studies | 23% ± 6% | |
hematopoietic precursor cell | 4 studies | 39% ± 10% | |
glomerular endothelial cell | 4 studies | 47% ± 7% | |
kidney loop of Henle epithelial cell | 4 studies | 25% ± 12% | |
podocyte | 4 studies | 52% ± 18% | |
lymphocyte | 4 studies | 32% ± 8% | |
luminal hormone-sensing cell of mammary gland | 4 studies | 33% ± 7% | |
cardiac muscle cell | 4 studies | 27% ± 2% | |
group 3 innate lymphoid cell | 4 studies | 41% ± 7% | |
melanocyte | 4 studies | 54% ± 19% | |
B cell | 4 studies | 24% ± 13% | |
Langerhans cell | 3 studies | 74% ± 5% | |
common myeloid progenitor | 3 studies | 27% ± 17% | |
retinal cone cell | 3 studies | 22% ± 4% | |
retinal pigment epithelial cell | 3 studies | 46% ± 21% | |
endocardial cell | 3 studies | 48% ± 8% | |
tissue-resident macrophage | 3 studies | 32% ± 16% | |
enterocyte | 3 studies | 23% ± 6% | |
Mueller cell | 3 studies | 21% ± 5% | |
retinal rod cell | 3 studies | 26% ± 6% | |
intermediate monocyte | 3 studies | 31% ± 11% | |
neuron | 3 studies | 35% ± 17% | |
muscle cell | 3 studies | 59% ± 12% | |
glutamatergic neuron | 3 studies | 30% ± 5% | |
pancreatic ductal cell | 3 studies | 56% ± 12% | |
enteroendocrine cell | 3 studies | 33% ± 17% | |
chondrocyte | 3 studies | 49% ± 19% | |
keratinocyte | 3 studies | 29% ± 12% | |
myoepithelial cell | 3 studies | 63% ± 13% | |
progenitor cell of mammary luminal epithelium | 3 studies | 36% ± 3% |
Name | Number of supported studies | Average coverage | |
---|---|---|---|
lung | 19 studies | 36% ± 15% | |
brain | 14 studies | 37% ± 17% | |
intestine | 10 studies | 26% ± 17% | |
heart | 7 studies | 35% ± 9% | |
eye | 6 studies | 33% ± 19% | |
kidney | 5 studies | 25% ± 5% | |
uterus | 5 studies | 52% ± 14% | |
adipose | 5 studies | 43% ± 23% | |
breast | 5 studies | 41% ± 16% | |
pancreas | 4 studies | 30% ± 9% | |
esophagus | 4 studies | 45% ± 17% | |
prostate | 4 studies | 25% ± 7% | |
skin | 4 studies | 39% ± 20% | |
peripheral blood | 3 studies | 27% ± 8% | |
placenta | 3 studies | 22% ± 5% | |
ovary | 3 studies | 26% ± 7% | |
liver | 3 studies | 30% ± 10% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
uterus | 100% | 94227.93 | 170 / 170 | 99% | 170.09 | 454 / 459 |
breast | 100% | 165190.25 | 459 / 459 | 98% | 141.35 | 1098 / 1118 |
thymus | 99% | 99684.13 | 649 / 653 | 99% | 398.18 | 596 / 605 |
esophagus | 99% | 102998.82 | 1428 / 1445 | 97% | 127.63 | 178 / 183 |
intestine | 98% | 81978.27 | 944 / 966 | 95% | 112.28 | 499 / 527 |
bladder | 100% | 113890.90 | 21 / 21 | 92% | 110.10 | 464 / 504 |
prostate | 91% | 46909.96 | 224 / 245 | 97% | 125.09 | 485 / 502 |
lung | 90% | 37952.94 | 520 / 578 | 97% | 142.92 | 1115 / 1155 |
skin | 83% | 51916.19 | 1495 / 1809 | 99% | 225.47 | 469 / 472 |
ovary | 86% | 34342.79 | 155 / 180 | 94% | 117.29 | 404 / 430 |
stomach | 79% | 47654.70 | 283 / 359 | 94% | 101.87 | 269 / 286 |
adrenal gland | 41% | 12300.94 | 107 / 258 | 94% | 100.25 | 216 / 230 |
kidney | 37% | 10791.33 | 33 / 89 | 94% | 142.54 | 850 / 901 |
brain | 27% | 9267.15 | 718 / 2642 | 97% | 134.34 | 686 / 705 |
pancreas | 5% | 1420.50 | 18 / 328 | 99% | 248.17 | 177 / 178 |
adipose | 100% | 215946.31 | 1204 / 1204 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 154.29 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 31.05 | 1 / 1 |
blood vessel | 100% | 148298.87 | 1334 / 1335 | 0% | 0 | 0 / 0 |
heart | 99% | 154862.47 | 854 / 861 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 93% | 87.60 | 27 / 29 |
eye | 0% | 0 | 0 / 0 | 85% | 72.11 | 68 / 80 |
muscle | 76% | 27724.61 | 609 / 803 | 0% | 0 | 0 / 0 |
liver | 0% | 0 | 0 / 226 | 67% | 43.96 | 270 / 406 |
spleen | 34% | 8764.32 | 81 / 241 | 0% | 0 | 0 / 0 |
peripheral blood | 15% | 3721.95 | 135 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_1903903 | Biological process | regulation of establishment of T cell polarity |
GO_0060271 | Biological process | cilium assembly |
GO_0035994 | Biological process | response to muscle stretch |
GO_1903923 | Biological process | positive regulation of protein processing in phagocytic vesicle |
GO_0071801 | Biological process | regulation of podosome assembly |
GO_0051016 | Biological process | barbed-end actin filament capping |
GO_0014891 | Biological process | striated muscle atrophy |
GO_0030042 | Biological process | actin filament depolymerization |
GO_0010628 | Biological process | positive regulation of gene expression |
GO_0030041 | Biological process | actin filament polymerization |
GO_1902174 | Biological process | positive regulation of keratinocyte apoptotic process |
GO_0030031 | Biological process | cell projection assembly |
GO_0022617 | Biological process | extracellular matrix disassembly |
GO_0051693 | Biological process | actin filament capping |
GO_0046597 | Biological process | negative regulation of viral entry into host cell |
GO_0031648 | Biological process | protein destabilization |
GO_0055119 | Biological process | relaxation of cardiac muscle |
GO_0086003 | Biological process | cardiac muscle cell contraction |
GO_0008154 | Biological process | actin polymerization or depolymerization |
GO_0006911 | Biological process | phagocytosis, engulfment |
GO_0042989 | Biological process | sequestering of actin monomers |
GO_0051014 | Biological process | actin filament severing |
GO_1990000 | Biological process | amyloid fibril formation |
GO_0051127 | Biological process | positive regulation of actin nucleation |
GO_0097284 | Biological process | hepatocyte apoptotic process |
GO_2001269 | Biological process | positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway |
GO_0007015 | Biological process | actin filament organization |
GO_1903909 | Biological process | regulation of receptor clustering |
GO_0007417 | Biological process | central nervous system development |
GO_0097017 | Biological process | renal protein absorption |
GO_0071346 | Biological process | cellular response to type II interferon |
GO_1903906 | Biological process | regulation of plasma membrane raft polarization |
GO_0005615 | Cellular component | extracellular space |
GO_0016528 | Cellular component | sarcoplasm |
GO_0005576 | Cellular component | extracellular region |
GO_0005886 | Cellular component | plasma membrane |
GO_0030478 | Cellular component | actin cap |
GO_0002102 | Cellular component | podosome |
GO_0070062 | Cellular component | extracellular exosome |
GO_0030864 | Cellular component | cortical actin cytoskeleton |
GO_0034774 | Cellular component | secretory granule lumen |
GO_0005925 | Cellular component | focal adhesion |
GO_0072562 | Cellular component | blood microparticle |
GO_0015629 | Cellular component | actin cytoskeleton |
GO_1904813 | Cellular component | ficolin-1-rich granule lumen |
GO_0005829 | Cellular component | cytosol |
GO_0045335 | Cellular component | phagocytic vesicle |
GO_0005737 | Cellular component | cytoplasm |
GO_0030027 | Cellular component | lamellipodium |
GO_0005634 | Cellular component | nucleus |
GO_0045159 | Molecular function | myosin II binding |
GO_0005546 | Molecular function | phosphatidylinositol-4,5-bisphosphate binding |
GO_0051015 | Molecular function | actin filament binding |
GO_0036313 | Molecular function | phosphatidylinositol 3-kinase catalytic subunit binding |
GO_0005509 | Molecular function | calcium ion binding |
GO_0005515 | Molecular function | protein binding |
GO_0003779 | Molecular function | actin binding |
Gene name | GSN |
Protein name | Gelsolin (ADF) (Actin-depolymerizing factor) Gelsolin Gelsolin (AGEL) (Actin-depolymerizing factor) (ADF) (Brevin) |
Synonyms | |
Description | FUNCTION: Calcium-regulated, actin-modulating protein that binds to the plus (or barbed) ends of actin monomers or filaments, preventing monomer exchange (end-blocking or capping). It can promote the assembly of monomers into filaments (nucleation) as well as sever filaments already formed . Plays a role in ciliogenesis . . FUNCTION: Calcium-regulated, actin-modulating protein that binds to the plus (or barbed) ends of actin monomers or filaments, preventing monomer exchange (end-blocking or capping). It can promote the assembly of monomers into filaments (nucleation) as well as sever filaments already formed. Plays a role in ciliogenesis. . FUNCTION: Calcium-regulated, actin-modulating protein that binds to the plus (or barbed) ends of actin monomers or filaments, preventing monomer exchange (end-blocking or capping). It can promote the assembly of monomers into filaments (nucleation) as well as sever filaments already formed. Plays a role in ciliogenesis. . FUNCTION: Calcium-regulated, actin-modulating protein that binds to the plus (or barbed) ends of actin monomers or filaments, preventing monomer exchange (end-blocking or capping). It can promote the assembly of monomers into filaments (nucleation) as well as sever filaments already formed. Plays a role in ciliogenesis. . FUNCTION: Calcium-regulated, actin-modulating protein that binds to the plus (or barbed) ends of actin monomers or filaments, preventing monomer exchange (end-blocking or capping). It can promote the assembly of monomers into filaments (nucleation) as well as sever filaments already formed. Plays a role in ciliogenesis. . FUNCTION: Calcium-regulated, actin-modulating protein that binds to the plus (or barbed) ends of actin monomers or filaments, preventing monomer exchange (end-blocking or capping). It can promote the assembly of monomers into filaments (nucleation) as well as sever filaments already formed. Plays a role in ciliogenesis. . |
Accessions | P06396 ENST00000432226.7 [P06396-2] ENST00000545652.6 [P06396-4] A0A8V8TND7 A0A0U1RQL8 Q5T0H8 ENST00000477104.2 A0A0A0MT01 ENST00000373808.8 [P06396-3] ENST00000373818.8 [P06396-1] ENST00000432226 A0A0A0MS51 ENST00000394353.7 ENST00000449733.7 Q5T0I0 ENST00000699558.1 ENST00000373823.7 [P06396-2] ENST00000373806.1 |