FRYL | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
endothelial cell	36 studies	46% ± 18%	Explore
astrocyte	18 studies	38% ± 17%	Explore
natural killer cell	17 studies	23% ± 9%	Explore
oligodendrocyte	17 studies	75% ± 20%	Explore
microglial cell	15 studies	47% ± 16%	Explore
capillary endothelial cell	14 studies	28% ± 16%	Explore
macrophage	13 studies	39% ± 19%	Explore
oligodendrocyte precursor cell	13 studies	42% ± 16%	Explore
B cell	13 studies	24% ± 10%	Explore
endothelial cell of artery	13 studies	31% ± 14%	Explore
GABAergic neuron	11 studies	50% ± 23%	Explore
glutamatergic neuron	11 studies	46% ± 24%	Explore
CD8-positive, alpha-beta T cell	11 studies	22% ± 6%	Explore
fibroblast	11 studies	33% ± 11%	Explore
mast cell	11 studies	27% ± 10%	Explore
smooth muscle cell	11 studies	33% ± 12%	Explore
T cell	10 studies	26% ± 10%	Explore
CD16-positive, CD56-dim natural killer cell, human	10 studies	21% ± 8%	Explore
pericyte	10 studies	41% ± 14%	Explore
epithelial cell	10 studies	39% ± 20%	Explore
regulatory T cell	10 studies	21% ± 7%	Explore
basal cell	10 studies	31% ± 23%	Explore
vein endothelial cell	10 studies	37% ± 24%	Explore
CD16-negative, CD56-bright natural killer cell, human	9 studies	22% ± 7%	Explore
endothelial cell of lymphatic vessel	8 studies	37% ± 18%	Explore
CD4-positive, alpha-beta T cell	8 studies	25% ± 8%	Explore
goblet cell	8 studies	46% ± 19%	Explore
plasmacytoid dendritic cell	8 studies	22% ± 8%	Explore
neuron	7 studies	45% ± 21%	Explore
myeloid cell	7 studies	30% ± 8%	Explore
retinal cone cell	7 studies	54% ± 23%	Explore
adipocyte	7 studies	27% ± 9%	Explore
dendritic cell	7 studies	36% ± 9%	Explore
effector memory CD8-positive, alpha-beta T cell	6 studies	24% ± 7%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	6 studies	22% ± 9%	Explore
interneuron	6 studies	63% ± 18%	Explore
ciliated cell	6 studies	29% ± 12%	Explore
Mueller cell	6 studies	45% ± 28%	Explore
retinal rod cell	6 studies	48% ± 21%	Explore
mature NK T cell	5 studies	22% ± 8%	Explore
mucosal invariant T cell	5 studies	22% ± 7%	Explore
cardiac muscle cell	5 studies	30% ± 7%	Explore
retina horizontal cell	5 studies	38% ± 16%	Explore
endothelial cell of vascular tree	5 studies	45% ± 26%	Explore
monocyte	5 studies	40% ± 7%	Explore
type I pneumocyte	5 studies	32% ± 9%	Explore
type II pneumocyte	5 studies	27% ± 8%	Explore
CD8-positive, alpha-beta memory T cell	5 studies	19% ± 3%	Explore
gamma-delta T cell	5 studies	21% ± 8%	Explore
naive B cell	5 studies	19% ± 2%	Explore
glial cell	4 studies	35% ± 15%	Explore
granule cell	4 studies	39% ± 7%	Explore
plasma cell	4 studies	34% ± 6%	Explore
mesothelial cell	4 studies	33% ± 10%	Explore
lymphocyte	4 studies	45% ± 17%	Explore
amacrine cell	4 studies	45% ± 15%	Explore
respiratory goblet cell	4 studies	33% ± 12%	Explore
club cell	4 studies	34% ± 9%	Explore
erythrocyte	4 studies	46% ± 22%	Explore
classical monocyte	3 studies	21% ± 4%	Explore
exhausted T cell	3 studies	21% ± 4%	Explore
glomerular endothelial cell	3 studies	20% ± 1%	Explore
differentiation-committed oligodendrocyte precursor	3 studies	54% ± 15%	Explore
GABAergic interneuron	3 studies	47% ± 5%	Explore
progenitor cell	3 studies	44% ± 16%	Explore
squamous epithelial cell	3 studies	36% ± 25%	Explore
mononuclear phagocyte	3 studies	29% ± 9%	Explore
non-classical monocyte	3 studies	25% ± 7%	Explore
retinal bipolar neuron	3 studies	28% ± 9%	Explore
GABAergic amacrine cell	3 studies	47% ± 12%	Explore
glycinergic amacrine cell	3 studies	38% ± 9%	Explore
retinal ganglion cell	3 studies	35% ± 15%	Explore
rod bipolar cell	3 studies	33% ± 17%	Explore
innate lymphoid cell	3 studies	17% ± 0%	Explore
hepatocyte	3 studies	46% ± 16%	Explore
effector memory CD4-positive, alpha-beta T cell	3 studies	18% ± 2%	Explore
ependymal cell	3 studies	36% ± 20%	Explore
alveolar macrophage	3 studies	41% ± 10%	Explore
leukocyte	3 studies	53% ± 4%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	3 studies	24% ± 10%	Explore
mural cell	3 studies	58% ± 6%	Explore
mucus secreting cell	3 studies	35% ± 7%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
brain	17 studies	52% ± 21%	Explore
lung	7 studies	27% ± 10%	Explore
eye	6 studies	52% ± 18%	Explore
heart	4 studies	34% ± 4%	Explore
adipose	4 studies	28% ± 8%	Explore
kidney	4 studies	22% ± 6%	Explore
peripheral blood	3 studies	24% ± 2%	Explore
liver	3 studies	35% ± 11%	Explore
intestine	3 studies	17% ± 1%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	3413.25	1445 / 1445	100%	17.14	183 / 183
brain	100%	3873.72	2634 / 2642	100%	14.79	704 / 705
intestine	100%	7049.95	966 / 966	99%	17.25	521 / 527
stomach	100%	2878.49	359 / 359	98%	16.64	281 / 286
breast	100%	4190.06	459 / 459	98%	14.85	1091 / 1118
lung	100%	4544.63	577 / 578	97%	9.78	1123 / 1155
prostate	100%	2885.33	245 / 245	97%	10.48	485 / 502
bladder	100%	3373.67	21 / 21	96%	11.02	485 / 504
kidney	100%	2268.73	89 / 89	96%	11.93	863 / 901
uterus	100%	3616.53	170 / 170	95%	9.50	436 / 459
thymus	100%	3103.82	652 / 653	95%	7.67	575 / 605
pancreas	96%	1677.58	315 / 328	98%	11.04	174 / 178
skin	100%	4152.50	1809 / 1809	92%	9.92	432 / 472
adrenal gland	100%	2825.84	258 / 258	90%	6.85	208 / 230
ovary	100%	2581.29	180 / 180	82%	5.04	352 / 430
liver	94%	1138.02	212 / 226	47%	2.51	190 / 406
adipose	100%	4283.85	1204 / 1204	0%	0	0 / 0
blood vessel	100%	5911.86	1335 / 1335	0%	0	0 / 0
lymph node	0%	0	0 / 0	100%	9.35	29 / 29
spleen	100%	4064.18	241 / 241	0%	0	0 / 0
ureter	0%	0	0 / 0	100%	3.10	1 / 1
heart	99%	2361.97	854 / 861	0%	0	0 / 0
muscle	99%	1822.02	793 / 803	0%	0	0 / 0
tonsil	0%	0	0 / 0	93%	11.45	42 / 45
peripheral blood	80%	2372.97	744 / 929	0%	0	0 / 0
eye	0%	0	0 / 0	75%	6.91	60 / 80
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

IV. Literature review

[source]

Gene name	FRYL
Protein name	Protein furry homolog-like (ALL1-fused gene from chromosome 4p12 protein) FRY like transcription coactivator
Synonyms	AF4P12 KIAA0826
Description	FUNCTION: Plays a key role in maintaining the integrity of polarized cell extensions during morphogenesis, regulates the actin cytoskeleton and plays a key role in patterning sensory neuron dendritic fields by promoting avoidance between homologous dendrites as well as by limiting dendritic branching (By similarity). May function as a transcriptional activator. .
Accessions	A0A286YEZ9 O94915 A0A2C9F2R7 ENST00000358350.9 [O94915-1] ENST00000505759.1 ENST00000503238.6 A0A669KB90 A0A6E1XQM6 D6R9B9 F2Z2S2 ENST00000507711.5 ENST00000641795.1 ENST00000507873.8 ENST00000514617.5 H0Y9X0 ENST00000673760.1

GO_0000902	Biological process	cell morphogenesis
GO_0031175	Biological process	neuron projection development
GO_0030427	Cellular component	site of polarized growth
GO_0005938	Cellular component	cell cortex

FRYL report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review