DUSP2 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0043409Biological processnegative regulation of MAPK cascade
GO_0001706Biological processendoderm formation
GO_0006470Biological processprotein dephosphorylation
GO_0035335Biological processpeptidyl-tyrosine dephosphorylation
GO_0005654Cellular componentnucleoplasm
GO_0031965Cellular componentnuclear membrane
GO_0005737Cellular componentcytoplasm
GO_0005634Cellular componentnucleus
GO_0051019Molecular functionmitogen-activated protein kinase binding
GO_0017017Molecular functionMAP kinase tyrosine/serine/threonine phosphatase activity
GO_0004725Molecular functionprotein tyrosine phosphatase activity
GO_0008330Molecular functionprotein tyrosine/threonine phosphatase activity
GO_0033550Molecular functionMAP kinase tyrosine phosphatase activity
GO_0005515Molecular functionprotein binding
GO_0017018Molecular functionmyosin phosphatase activity

IV. Literature review

[source]
Gene nameDUSP2
Protein nameDual specificity protein phosphatase 2 (EC 3.1.3.16) (EC 3.1.3.48) (Dual specificity protein phosphatase PAC-1)
SynonymsPAC1
DescriptionFUNCTION: Dephosphorylates both phosphorylated Thr and Tyr residues in MAPK1, and dephosphorylation of phosphotyrosine is slightly faster than that of phosphothreonine . Can dephosphorylate MAPK1 (By similarity). .

AccessionsQ05923
ENST00000288943.5