DENND4A report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0032483Biological processregulation of Rab protein signal transduction
GO_0006355Biological processregulation of DNA-templated transcription
GO_0005829Cellular componentcytosol
GO_0031410Cellular componentcytoplasmic vesicle
GO_0005634Cellular componentnucleus
GO_0003677Molecular functionDNA binding
GO_0005085Molecular functionguanyl-nucleotide exchange factor activity
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameDENND4A
Protein nameDENND4A protein
C-myc promoter-binding protein (DENN domain-containing protein 4A)
DENN domain containing 4A
SynonymsMYCPBP
IRLB
DescriptionFUNCTION: Probable guanine nucleotide exchange factor (GEF) which may activate RAB10. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form. According to PubMed:8056341, it may bind to ISRE-like element (interferon-stimulated response element) of MYC P2 promoter. .

AccessionsH3BSA0
A0A7I2RAZ6
H3BTW5
ENST00000431932.6 [Q7Z401-1]
ENST00000635620.2
ENST00000443035.8
Q05C90
Q7Z401
A0A0U1RR27
ENST00000564674.5
ENST00000561863.1