COX20 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
smooth muscle cell	22 studies	25% ± 6%	Explore
natural killer cell	17 studies	21% ± 5%	Explore
pericyte	14 studies	23% ± 7%	Explore
endothelial cell	13 studies	25% ± 9%	Explore
T cell	12 studies	20% ± 5%	Explore
macrophage	12 studies	23% ± 7%	Explore
regulatory T cell	12 studies	20% ± 4%	Explore
CD4-positive, alpha-beta T cell	11 studies	22% ± 5%	Explore
CD8-positive, alpha-beta T cell	11 studies	21% ± 4%	Explore
epithelial cell	11 studies	39% ± 20%	Explore
fibroblast	11 studies	23% ± 11%	Explore
astrocyte	11 studies	27% ± 11%	Explore
basal cell	10 studies	27% ± 14%	Explore
B cell	9 studies	22% ± 7%	Explore
mast cell	9 studies	21% ± 4%	Explore
gamma-delta T cell	9 studies	26% ± 12%	Explore
myofibroblast cell	8 studies	22% ± 6%	Explore
endothelial cell of lymphatic vessel	7 studies	23% ± 7%	Explore
naive B cell	7 studies	20% ± 5%	Explore
CD16-positive, CD56-dim natural killer cell, human	7 studies	20% ± 4%	Explore
conventional dendritic cell	7 studies	28% ± 14%	Explore
epithelial cell of proximal tubule	7 studies	33% ± 10%	Explore
ciliated cell	7 studies	35% ± 16%	Explore
CD8-positive, alpha-beta memory T cell	6 studies	21% ± 4%	Explore
non-classical monocyte	6 studies	27% ± 10%	Explore
mature NK T cell	6 studies	21% ± 4%	Explore
kidney loop of Henle epithelial cell	6 studies	36% ± 7%	Explore
monocyte	6 studies	19% ± 3%	Explore
memory B cell	6 studies	18% ± 3%	Explore
abnormal cell	6 studies	37% ± 11%	Explore
neuron	6 studies	35% ± 17%	Explore
secretory cell	5 studies	27% ± 16%	Explore
CD16-negative, CD56-bright natural killer cell, human	5 studies	19% ± 2%	Explore
effector memory CD8-positive, alpha-beta T cell	5 studies	22% ± 4%	Explore
kidney distal convoluted tubule epithelial cell	5 studies	42% ± 8%	Explore
retinal rod cell	5 studies	35% ± 14%	Explore
GABAergic neuron	5 studies	34% ± 10%	Explore
glutamatergic neuron	5 studies	37% ± 16%	Explore
oligodendrocyte precursor cell	5 studies	27% ± 8%	Explore
interneuron	5 studies	31% ± 14%	Explore
oligodendrocyte	5 studies	23% ± 3%	Explore
club cell	4 studies	20% ± 5%	Explore
ionocyte	4 studies	26% ± 8%	Explore
leukocyte	4 studies	24% ± 8%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	4 studies	20% ± 2%	Explore
renal alpha-intercalated cell	4 studies	33% ± 13%	Explore
transit amplifying cell	4 studies	20% ± 3%	Explore
retinal ganglion cell	4 studies	50% ± 26%	Explore
brush cell	4 studies	30% ± 11%	Explore
precursor B cell	4 studies	24% ± 8%	Explore
type II pneumocyte	4 studies	31% ± 20%	Explore
amacrine cell	4 studies	38% ± 17%	Explore
retina horizontal cell	4 studies	33% ± 16%	Explore
retinal cone cell	4 studies	63% ± 27%	Explore
microglial cell	4 studies	25% ± 5%	Explore
Mueller cell	4 studies	27% ± 8%	Explore
dendritic cell	4 studies	34% ± 16%	Explore
luminal hormone-sensing cell of mammary gland	4 studies	26% ± 6%	Explore
endothelial cell of vascular tree	4 studies	21% ± 4%	Explore
connective tissue cell	4 studies	21% ± 5%	Explore
CD4-positive, alpha-beta memory T cell	3 studies	20% ± 4%	Explore
deuterosomal cell	3 studies	41% ± 2%	Explore
effector CD8-positive, alpha-beta T cell	3 studies	21% ± 3%	Explore
hematopoietic precursor cell	3 studies	31% ± 13%	Explore
progenitor cell	3 studies	18% ± 2%	Explore
retinal bipolar neuron	3 studies	48% ± 17%	Explore
placental villous trophoblast	3 studies	36% ± 16%	Explore
lymphocyte	3 studies	29% ± 9%	Explore
myeloid cell	3 studies	28% ± 12%	Explore
neuroendocrine cell	3 studies	27% ± 8%	Explore
enterocyte	3 studies	19% ± 3%	Explore
retinal pigment epithelial cell	3 studies	40% ± 21%	Explore
OFF-bipolar cell	3 studies	30% ± 9%	Explore
ON-bipolar cell	3 studies	29% ± 9%	Explore
rod bipolar cell	3 studies	44% ± 13%	Explore
T follicular helper cell	3 studies	17% ± 1%	Explore
effector memory CD4-positive, alpha-beta T cell	3 studies	24% ± 4%	Explore
innate lymphoid cell	3 studies	25% ± 2%	Explore
goblet cell	3 studies	30% ± 12%	Explore
group 3 innate lymphoid cell	3 studies	27% ± 10%	Explore
mucosal invariant T cell	3 studies	18% ± 1%	Explore
T-helper 17 cell	3 studies	21% ± 3%	Explore
hepatocyte	3 studies	49% ± 31%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
lung	11 studies	25% ± 12%	Explore
kidney	9 studies	22% ± 5%	Explore
brain	9 studies	29% ± 11%	Explore
eye	8 studies	32% ± 15%	Explore
intestine	6 studies	22% ± 8%	Explore
liver	6 studies	27% ± 17%	Explore
peripheral blood	5 studies	24% ± 10%	Explore
uterus	4 studies	26% ± 11%	Explore
pancreas	3 studies	27% ± 10%	Explore
breast	3 studies	18% ± 1%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
brain	100%	165.58	2639 / 2642	54%	1.02	384 / 705
esophagus	98%	80.62	1420 / 1445	40%	0.65	73 / 183
breast	99%	66.10	456 / 459	28%	0.59	311 / 1118
thymus	100%	100.44	651 / 653	25%	0.37	153 / 605
intestine	100%	81.25	962 / 966	22%	0.38	117 / 527
stomach	97%	60.82	350 / 359	23%	0.45	65 / 286
ovary	100%	166.72	180 / 180	20%	0.32	84 / 430
lung	97%	52.97	558 / 578	21%	0.52	244 / 1155
kidney	100%	99.27	89 / 89	17%	0.29	154 / 901
bladder	100%	86.38	21 / 21	15%	0.37	74 / 504
prostate	100%	85.38	244 / 245	13%	0.24	63 / 502
uterus	100%	123.43	170 / 170	9%	0.17	42 / 459
adrenal gland	100%	88.29	257 / 258	3%	0.05	8 / 230
blood vessel	100%	86.81	1335 / 1335	0%	0	0 / 0
spleen	100%	55.76	241 / 241	0%	0	0 / 0
muscle	99%	77.51	796 / 803	0%	0	0 / 0
adipose	99%	58.73	1193 / 1204	0%	0	0 / 0
skin	89%	35.40	1607 / 1809	9%	0.12	41 / 472
heart	95%	83.30	822 / 861	0%	0	0 / 0
pancreas	88%	30.88	287 / 328	6%	0.11	11 / 178
liver	77%	23.63	174 / 226	3%	0.05	14 / 406
peripheral blood	41%	21.85	380 / 929	0%	0	0 / 0
lymph node	0%	0	0 / 0	10%	0.13	3 / 29
eye	0%	0	0 / 0	9%	0.12	7 / 80
tonsil	0%	0	0 / 0	2%	0.02	1 / 45
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

IV. Literature review

[source]

Gene name	COX20
Protein name	Cytochrome c oxidase assembly protein COX20, mitochondrial
Synonyms	FAM36A
Description	FUNCTION: Essential for the assembly of the mitochondrial respiratory chain complex IV (CIV), also known as cytochrome c oxidase . Acts as a chaperone in the early steps of cytochrome c oxidase subunit II (MT-CO2/COX2) maturation, stabilizing the newly synthesized protein and presenting it to metallochaperones SCO1/2 which in turn facilitates the incorporation of the mature MT-CO2/COX2 into the assembling CIV holoenzyme . .
Accessions	Q5RI15 ENST00000411948.7 [Q5RI15-1] ENST00000366528.3 [Q5RI15-2]

GO_0033617	Biological process	mitochondrial cytochrome c oxidase assembly
GO_0005743	Cellular component	mitochondrial inner membrane
GO_0005739	Cellular component	mitochondrion
GO_0005515	Molecular function	protein binding

COX20 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review