CEP350 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
endothelial cell	28 studies	33% ± 14%	Explore
macrophage	27 studies	29% ± 15%	Explore
astrocyte	18 studies	40% ± 21%	Explore
fibroblast	17 studies	26% ± 11%	Explore
B cell	16 studies	22% ± 5%	Explore
pericyte	16 studies	26% ± 11%	Explore
dendritic cell	15 studies	38% ± 14%	Explore
natural killer cell	15 studies	22% ± 4%	Explore
CD8-positive, alpha-beta T cell	15 studies	20% ± 4%	Explore
classical monocyte	14 studies	23% ± 7%	Explore
oligodendrocyte	14 studies	41% ± 14%	Explore
oligodendrocyte precursor cell	13 studies	37% ± 16%	Explore
microglial cell	13 studies	45% ± 15%	Explore
glutamatergic neuron	12 studies	40% ± 24%	Explore
smooth muscle cell	11 studies	25% ± 8%	Explore
ciliated cell	11 studies	27% ± 11%	Explore
T cell	10 studies	24% ± 9%	Explore
GABAergic neuron	10 studies	42% ± 22%	Explore
CD4-positive, alpha-beta T cell	10 studies	20% ± 3%	Explore
monocyte	9 studies	28% ± 11%	Explore
CD16-positive, CD56-dim natural killer cell, human	9 studies	21% ± 4%	Explore
CD8-positive, alpha-beta memory T cell	9 studies	22% ± 3%	Explore
naive B cell	9 studies	21% ± 3%	Explore
non-classical monocyte	9 studies	23% ± 7%	Explore
conventional dendritic cell	9 studies	23% ± 12%	Explore
effector memory CD8-positive, alpha-beta T cell	9 studies	21% ± 3%	Explore
mucosal invariant T cell	9 studies	19% ± 3%	Explore
myeloid cell	9 studies	33% ± 6%	Explore
epithelial cell	9 studies	37% ± 18%	Explore
adipocyte	9 studies	35% ± 11%	Explore
gamma-delta T cell	9 studies	21% ± 8%	Explore
regulatory T cell	9 studies	21% ± 4%	Explore
plasmacytoid dendritic cell	9 studies	22% ± 8%	Explore
CD16-negative, CD56-bright natural killer cell, human	8 studies	19% ± 2%	Explore
endothelial cell of lymphatic vessel	7 studies	31% ± 14%	Explore
type I pneumocyte	7 studies	22% ± 7%	Explore
interneuron	7 studies	45% ± 25%	Explore
basal cell	7 studies	29% ± 15%	Explore
memory B cell	7 studies	20% ± 4%	Explore
mast cell	6 studies	23% ± 10%	Explore
plasma cell	6 studies	30% ± 11%	Explore
leukocyte	6 studies	27% ± 9%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	6 studies	22% ± 4%	Explore
mature NK T cell	6 studies	21% ± 4%	Explore
neuron	6 studies	42% ± 18%	Explore
club cell	6 studies	26% ± 7%	Explore
retina horizontal cell	6 studies	25% ± 9%	Explore
retinal cone cell	6 studies	24% ± 10%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	5 studies	21% ± 4%	Explore
capillary endothelial cell	5 studies	23% ± 3%	Explore
cardiac muscle cell	5 studies	32% ± 10%	Explore
endothelial cell of artery	5 studies	17% ± 3%	Explore
amacrine cell	5 studies	27% ± 8%	Explore
endothelial cell of vascular tree	5 studies	27% ± 15%	Explore
effector memory CD4-positive, alpha-beta T cell	5 studies	20% ± 3%	Explore
goblet cell	5 studies	29% ± 22%	Explore
type II pneumocyte	5 studies	25% ± 7%	Explore
CD4-positive, alpha-beta memory T cell	4 studies	20% ± 5%	Explore
deuterosomal cell	4 studies	39% ± 8%	Explore
hematopoietic precursor cell	4 studies	28% ± 12%	Explore
granule cell	4 studies	29% ± 3%	Explore
retinal ganglion cell	4 studies	26% ± 10%	Explore
retinal bipolar neuron	4 studies	20% ± 3%	Explore
mesothelial cell	4 studies	25% ± 6%	Explore
lymphocyte	4 studies	35% ± 8%	Explore
retinal rod cell	4 studies	29% ± 5%	Explore
respiratory goblet cell	4 studies	27% ± 5%	Explore
connective tissue cell	4 studies	23% ± 5%	Explore
alveolar macrophage	4 studies	32% ± 13%	Explore
ionocyte	3 studies	25% ± 6%	Explore
plasmablast	3 studies	31% ± 11%	Explore
glomerular endothelial cell	3 studies	23% ± 2%	Explore
GABAergic interneuron	3 studies	33% ± 3%	Explore
glial cell	3 studies	26% ± 5%	Explore
progenitor cell	3 studies	24% ± 5%	Explore
retinal pigment epithelial cell	3 studies	31% ± 18%	Explore
mononuclear phagocyte	3 studies	30% ± 6%	Explore
vein endothelial cell	3 studies	33% ± 16%	Explore
GABAergic amacrine cell	3 studies	29% ± 11%	Explore
Mueller cell	3 studies	31% ± 11%	Explore
OFF-bipolar cell	3 studies	26% ± 7%	Explore
ON-bipolar cell	3 studies	27% ± 8%	Explore
glycinergic amacrine cell	3 studies	27% ± 5%	Explore
rod bipolar cell	3 studies	27% ± 9%	Explore
secretory cell	3 studies	24% ± 6%	Explore
innate lymphoid cell	3 studies	20% ± 5%	Explore
hepatocyte	3 studies	42% ± 20%	Explore
abnormal cell	3 studies	32% ± 15%	Explore
neural progenitor cell	3 studies	28% ± 1%	Explore
ependymal cell	3 studies	42% ± 19%	Explore
enteroendocrine cell	3 studies	24% ± 3%	Explore
myofibroblast cell	3 studies	25% ± 9%	Explore
muscle cell	3 studies	42% ± 25%	Explore
transit amplifying cell	3 studies	38% ± 27%	Explore
mural cell	3 studies	38% ± 8%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
brain	19 studies	38% ± 21%	Explore
lung	9 studies	24% ± 7%	Explore
peripheral blood	9 studies	22% ± 6%	Explore
eye	7 studies	29% ± 15%	Explore
heart	4 studies	30% ± 7%	Explore
liver	4 studies	30% ± 14%	Explore
adipose	4 studies	27% ± 5%	Explore
bone marrow	3 studies	23% ± 7%	Explore
intestine	3 studies	19% ± 3%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	3515.35	1445 / 1445	100%	22.31	183 / 183
lung	100%	3583.29	577 / 578	100%	15.60	1154 / 1155
breast	100%	3905.37	459 / 459	100%	25.16	1115 / 1118
uterus	100%	3972.98	170 / 170	99%	14.24	456 / 459
brain	99%	2728.12	2628 / 2642	100%	17.11	703 / 705
pancreas	100%	2024.03	327 / 328	99%	12.52	177 / 178
thymus	100%	3482.30	653 / 653	99%	12.75	598 / 605
bladder	100%	4093.90	21 / 21	98%	11.89	494 / 504
prostate	100%	3200.09	245 / 245	97%	11.03	489 / 502
stomach	100%	3105.33	359 / 359	97%	13.72	277 / 286
intestine	100%	3760.86	966 / 966	96%	11.06	508 / 527
ovary	100%	4300.13	180 / 180	95%	7.05	409 / 430
adrenal gland	100%	2848.14	258 / 258	94%	8.73	217 / 230
skin	100%	4495.48	1809 / 1809	94%	17.82	443 / 472
kidney	100%	2070.13	89 / 89	93%	10.59	835 / 901
liver	100%	1446.87	226 / 226	91%	8.10	371 / 406
blood vessel	100%	4071.88	1335 / 1335	0%	0	0 / 0
lymph node	0%	0	0 / 0	100%	13.76	29 / 29
muscle	100%	7565.86	803 / 803	0%	0	0 / 0
spleen	100%	3298.55	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	15.52	45 / 45
ureter	0%	0	0 / 0	100%	5.18	1 / 1
adipose	100%	4358.37	1203 / 1204	0%	0	0 / 0
heart	96%	2195.50	825 / 861	0%	0	0 / 0
peripheral blood	88%	2665.56	816 / 929	0%	0	0 / 0
eye	0%	0	0 / 0	57%	4.39	46 / 80
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_1905515	Biological process	non-motile cilium assembly
GO_0071539	Biological process	protein localization to centrosome
GO_0034453	Biological process	microtubule anchoring
GO_0005814	Cellular component	centriole
GO_0042995	Cellular component	cell projection
GO_0005813	Cellular component	centrosome
GO_0005819	Cellular component	spindle
GO_0016020	Cellular component	membrane
GO_0005737	Cellular component	cytoplasm
GO_0005634	Cellular component	nucleus
GO_0008017	Molecular function	microtubule binding
GO_0005515	Molecular function	protein binding

IV. Literature review

[source]

Gene name	CEP350
Protein name	Centrosomal protein 350 Alternative protein CEP350 CEP350 protein Centrosome-associated protein 350 (Cep350) (Centrosome-associated protein of 350 kDa)
Synonyms	GM133 CAP350 KIAA0480
Description	FUNCTION: Plays an essential role in centriole growth by stabilizing a procentriolar seed composed of at least, SASS6 and CENPJ . Required for anchoring microtubules to the centrosomes and for the integrity of the microtubule network . Recruits PPARA to discrete subcellular compartments and thereby modulates PPARA activity . Required for ciliation . .
Accessions	L8ECF2 ENST00000706241.1 A0A994J5T9 ENST00000367607.8 ENST00000490047.2 H0Y7F7 Q05D72 ENST00000706263.1 ENST00000417046.2 ENST00000429851.6 A0A994J5V0 A0A994J5G8 ENST00000418229.6 Q5T2X5 ENST00000706265.1 ENST00000437245.2 ENST00000706234.1 ENST00000706262.1 H0YD38 Q5T2X4 Q5VT06

CEP350 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review