BRI3 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
macrophage	41 studies	51% ± 20%	Explore
endothelial cell	38 studies	40% ± 19%	Explore
fibroblast	29 studies	34% ± 14%	Explore
classical monocyte	27 studies	52% ± 22%	Explore
pericyte	26 studies	31% ± 13%	Explore
non-classical monocyte	24 studies	56% ± 25%	Explore
monocyte	22 studies	44% ± 22%	Explore
conventional dendritic cell	20 studies	41% ± 17%	Explore
endothelial cell of lymphatic vessel	19 studies	42% ± 18%	Explore
smooth muscle cell	18 studies	32% ± 12%	Explore
ciliated cell	18 studies	40% ± 21%	Explore
myeloid cell	15 studies	51% ± 25%	Explore
epithelial cell	14 studies	50% ± 19%	Explore
basal cell	13 studies	40% ± 16%	Explore
dendritic cell	12 studies	52% ± 25%	Explore
plasmacytoid dendritic cell	12 studies	41% ± 16%	Explore
vein endothelial cell	12 studies	37% ± 10%	Explore
capillary endothelial cell	11 studies	36% ± 6%	Explore
type II pneumocyte	10 studies	51% ± 24%	Explore
neutrophil	10 studies	46% ± 12%	Explore
secretory cell	10 studies	38% ± 18%	Explore
endothelial cell of artery	10 studies	38% ± 12%	Explore
endothelial cell of vascular tree	10 studies	47% ± 14%	Explore
type I pneumocyte	9 studies	46% ± 17%	Explore
leukocyte	9 studies	37% ± 14%	Explore
connective tissue cell	9 studies	33% ± 15%	Explore
alveolar macrophage	8 studies	63% ± 24%	Explore
myofibroblast cell	8 studies	26% ± 11%	Explore
microglial cell	8 studies	36% ± 14%	Explore
mast cell	7 studies	32% ± 11%	Explore
abnormal cell	7 studies	47% ± 14%	Explore
goblet cell	7 studies	29% ± 10%	Explore
B cell	6 studies	26% ± 10%	Explore
natural killer cell	6 studies	18% ± 2%	Explore
club cell	6 studies	37% ± 17%	Explore
respiratory goblet cell	6 studies	31% ± 13%	Explore
mononuclear phagocyte	6 studies	54% ± 14%	Explore
enterocyte	6 studies	31% ± 7%	Explore
ionocyte	5 studies	36% ± 14%	Explore
astrocyte	5 studies	25% ± 7%	Explore
intermediate monocyte	5 studies	54% ± 23%	Explore
neuron	5 studies	38% ± 14%	Explore
duct epithelial cell	4 studies	20% ± 3%	Explore
pancreatic A cell	4 studies	46% ± 6%	Explore
type B pancreatic cell	4 studies	59% ± 11%	Explore
hematopoietic precursor cell	4 studies	36% ± 24%	Explore
epithelial cell of proximal tubule	4 studies	35% ± 16%	Explore
kidney loop of Henle epithelial cell	4 studies	26% ± 13%	Explore
retinal ganglion cell	4 studies	45% ± 20%	Explore
progenitor cell	4 studies	19% ± 2%	Explore
amacrine cell	4 studies	33% ± 11%	Explore
retina horizontal cell	4 studies	38% ± 13%	Explore
retinal pigment epithelial cell	4 studies	50% ± 18%	Explore
adventitial cell	4 studies	27% ± 7%	Explore
lymphocyte	4 studies	31% ± 17%	Explore
enteroendocrine cell	4 studies	36% ± 10%	Explore
hepatocyte	4 studies	48% ± 23%	Explore
oligodendrocyte	4 studies	28% ± 7%	Explore
squamous epithelial cell	3 studies	42% ± 30%	Explore
pancreatic D cell	3 studies	59% ± 6%	Explore
monocyte-derived dendritic cell	3 studies	57% ± 22%	Explore
naive B cell	3 studies	20% ± 4%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	3 studies	31% ± 9%	Explore
mature NK T cell	3 studies	19% ± 2%	Explore
intestinal crypt stem cell	3 studies	25% ± 11%	Explore
retinal bipolar neuron	3 studies	22% ± 4%	Explore
extravillous trophoblast	3 studies	83% ± 8%	Explore
placental villous trophoblast	3 studies	59% ± 26%	Explore
plasma cell	3 studies	32% ± 11%	Explore
neuroendocrine cell	3 studies	55% ± 17%	Explore
retinal cone cell	3 studies	34% ± 11%	Explore
mucus secreting cell	3 studies	31% ± 4%	Explore
tissue-resident macrophage	3 studies	50% ± 14%	Explore
Mueller cell	3 studies	29% ± 14%	Explore
luminal hormone-sensing cell of mammary gland	3 studies	31% ± 2%	Explore
regulatory T cell	3 studies	19% ± 3%	Explore
mesothelial cell	3 studies	30% ± 12%	Explore
inflammatory macrophage	3 studies	43% ± 11%	Explore
luminal cell of prostate epithelium	3 studies	67% ± 6%	Explore
GABAergic neuron	3 studies	33% ± 14%	Explore
glutamatergic neuron	3 studies	40% ± 15%	Explore
acinar cell	3 studies	53% ± 12%	Explore
pancreatic ductal cell	3 studies	60% ± 5%	Explore
oligodendrocyte precursor cell	3 studies	25% ± 3%	Explore
hematopoietic stem cell	3 studies	25% ± 8%	Explore
glial cell	3 studies	29% ± 8%	Explore
melanocyte	3 studies	44% ± 11%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
lung	17 studies	38% ± 15%	Explore
intestine	10 studies	28% ± 10%	Explore
peripheral blood	9 studies	35% ± 14%	Explore
brain	7 studies	33% ± 11%	Explore
eye	6 studies	30% ± 9%	Explore
uterus	5 studies	41% ± 17%	Explore
liver	5 studies	28% ± 4%	Explore
pancreas	4 studies	52% ± 6%	Explore
kidney	4 studies	35% ± 13%	Explore
placenta	4 studies	58% ± 24%	Explore
adipose	4 studies	19% ± 3%	Explore
breast	3 studies	38% ± 4%	Explore
prostate	3 studies	39% ± 11%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	3585.88	1445 / 1445	100%	52.43	183 / 183
ovary	100%	3537.07	180 / 180	100%	52.52	430 / 430
pancreas	100%	3825.99	328 / 328	100%	66.45	178 / 178
prostate	100%	4564.93	245 / 245	100%	75.86	502 / 502
stomach	100%	5609.56	359 / 359	100%	63.44	286 / 286
uterus	100%	3753.04	170 / 170	100%	48.58	459 / 459
skin	100%	5373.55	1808 / 1809	100%	96.59	472 / 472
lung	100%	8828.70	578 / 578	100%	59.99	1154 / 1155
kidney	100%	5283.84	89 / 89	100%	61.49	900 / 901
thymus	100%	4450.68	653 / 653	100%	55.61	604 / 605
intestine	100%	4334.28	966 / 966	100%	57.11	526 / 527
liver	100%	4114.96	226 / 226	100%	66.94	405 / 406
bladder	100%	4876.90	21 / 21	100%	53.80	502 / 504
breast	100%	5475.60	459 / 459	99%	40.13	1109 / 1118
adrenal gland	100%	6899.97	258 / 258	99%	45.67	228 / 230
brain	99%	2203.86	2613 / 2642	100%	42.52	705 / 705
adipose	100%	6495.78	1204 / 1204	0%	0	0 / 0
eye	0%	0	0 / 0	100%	101.32	80 / 80
lymph node	0%	0	0 / 0	100%	62.46	29 / 29
spleen	100%	6102.78	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	34.44	45 / 45
ureter	0%	0	0 / 0	100%	26.09	1 / 1
blood vessel	100%	5598.49	1334 / 1335	0%	0	0 / 0
muscle	100%	7141.65	802 / 803	0%	0	0 / 0
heart	100%	3980.11	859 / 861	0%	0	0 / 0
peripheral blood	100%	7711.47	926 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0035577	Cellular component	azurophil granule membrane
GO_0005886	Cellular component	plasma membrane
GO_0048471	Cellular component	perinuclear region of cytoplasm
GO_0005634	Cellular component	nucleus
GO_0042802	Molecular function	identical protein binding
GO_0005515	Molecular function	protein binding

IV. Literature review

[source]

Gene name	BRI3
Protein name	Brain protein I3 Membrane protein BRI3 (Brain protein I3) (pRGR2)
Synonyms
Description	FUNCTION: Participates in tumor necrosis factor-alpha (TNF)-induced cell death . May be a target of Wnt/beta-catenin signaling in the liver . .
Accessions	ENST00000297290.4 [O95415-1] ENST00000539286.5 [O95415-2] O95415 ENST00000491463.4 I3L1V6

BRI3 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review