BIN2 report

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I. Expression across cell types

Cell ontologyData table

Name	Number of supported studies	Average coverage
natural killer cell	44 studies	50% ± 17%	Explore
CD8-positive, alpha-beta T cell	33 studies	35% ± 15%	Explore
CD4-positive, alpha-beta T cell	32 studies	32% ± 13%	Explore
T cell	31 studies	29% ± 10%	Explore
non-classical monocyte	24 studies	43% ± 18%	Explore
mature NK T cell	22 studies	43% ± 16%	Explore
regulatory T cell	22 studies	34% ± 12%	Explore
classical monocyte	20 studies	31% ± 16%	Explore
gamma-delta T cell	18 studies	39% ± 13%	Explore
monocyte	17 studies	26% ± 9%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	17 studies	32% ± 12%	Explore
CD16-negative, CD56-bright natural killer cell, human	16 studies	48% ± 16%	Explore
mucosal invariant T cell	16 studies	37% ± 14%	Explore
CD16-positive, CD56-dim natural killer cell, human	16 studies	61% ± 15%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	14 studies	38% ± 13%	Explore
effector memory CD8-positive, alpha-beta T cell	12 studies	42% ± 17%	Explore
CD4-positive, alpha-beta memory T cell	12 studies	31% ± 10%	Explore
CD8-positive, alpha-beta memory T cell	12 studies	36% ± 14%	Explore
platelet	11 studies	41% ± 11%	Explore
B cell	10 studies	20% ± 5%	Explore
naive B cell	10 studies	18% ± 2%	Explore
microglial cell	10 studies	31% ± 12%	Explore
macrophage	10 studies	24% ± 7%	Explore
innate lymphoid cell	7 studies	36% ± 16%	Explore
effector CD8-positive, alpha-beta T cell	7 studies	36% ± 17%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	6 studies	42% ± 13%	Explore
plasmacytoid dendritic cell	6 studies	27% ± 7%	Explore
leukocyte	6 studies	25% ± 5%	Explore
megakaryocyte	6 studies	68% ± 19%	Explore
hematopoietic stem cell	6 studies	29% ± 14%	Explore
memory B cell	6 studies	19% ± 2%	Explore
effector memory CD4-positive, alpha-beta T cell	6 studies	42% ± 16%	Explore
hematopoietic precursor cell	5 studies	24% ± 6%	Explore
exhausted T cell	5 studies	38% ± 15%	Explore
neutrophil	5 studies	24% ± 11%	Explore
lymphocyte	5 studies	34% ± 5%	Explore
myeloid cell	5 studies	27% ± 7%	Explore
T follicular helper cell	5 studies	25% ± 10%	Explore
central memory CD8-positive, alpha-beta T cell	4 studies	32% ± 12%	Explore
conventional dendritic cell	4 studies	34% ± 16%	Explore
effector CD4-positive, alpha-beta T cell	4 studies	46% ± 9%	Explore
T-helper 17 cell	4 studies	20% ± 2%	Explore
double negative thymocyte	4 studies	41% ± 16%	Explore
CD4-positive helper T cell	3 studies	23% ± 5%	Explore
CD4-positive, alpha-beta cytotoxic T cell	3 studies	30% ± 8%	Explore
plasmablast	3 studies	27% ± 11%	Explore
intraepithelial lymphocyte	3 studies	26% ± 8%	Explore
dendritic cell	3 studies	36% ± 17%	Explore
megakaryocyte-erythroid progenitor cell	3 studies	32% ± 13%	Explore
group 3 innate lymphoid cell	3 studies	38% ± 12%	Explore
mast cell	3 studies	29% ± 12%	Explore
central memory CD4-positive, alpha-beta T cell	3 studies	43% ± 9%	Explore

II. Expression across tissues

sc-RNAseq dataData table

Name	Number of supported studies	Average coverage
peripheral blood	19 studies	36% ± 13%	Explore
lung	3 studies	21% ± 4%	Explore
placenta	3 studies	19% ± 4%	Explore
lymph node	3 studies	20% ± 4%	Explore
liver	3 studies	24% ± 8%	Explore

Bulk RNAseq dataData table

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
lung	100%	2506.98	578 / 578	94%	10.26	1090 / 1155
breast	80%	337.08	366 / 459	95%	9.71	1062 / 1118
intestine	77%	776.46	745 / 966	91%	6.38	478 / 527
kidney	73%	347.20	65 / 89	95%	11.35	853 / 901
stomach	73%	311.60	263 / 359	92%	7.67	263 / 286
thymus	74%	363.34	484 / 653	78%	11.34	472 / 605
prostate	79%	347.47	194 / 245	67%	3.06	334 / 502
liver	86%	341.57	195 / 226	57%	3.17	230 / 406
bladder	71%	402.05	15 / 21	69%	5.15	350 / 504
brain	45%	189.92	1185 / 2642	95%	10.05	669 / 705
uterus	54%	169.96	92 / 170	81%	6.38	373 / 459
esophagus	54%	185.93	775 / 1445	81%	5.31	148 / 183
adrenal gland	84%	340.51	217 / 258	45%	1.88	103 / 230
pancreas	16%	56.92	53 / 328	88%	8.36	156 / 178
lymph node	0%	0	0 / 0	100%	43.09	29 / 29
peripheral blood	100%	19193.90	929 / 929	0%	0	0 / 0
spleen	100%	8247.96	241 / 241	0%	0	0 / 0
skin	22%	61.34	398 / 1809	76%	9.27	361 / 472
adipose	97%	690.09	1164 / 1204	0%	0	0 / 0
ovary	17%	56.21	31 / 180	77%	4.56	329 / 430
tonsil	0%	0	0 / 0	89%	11.06	40 / 45
blood vessel	53%	271.28	703 / 1335	0%	0	0 / 0
heart	44%	149.04	381 / 861	0%	0	0 / 0
eye	0%	0	0 / 0	20%	1.23	16 / 80
muscle	3%	7.11	22 / 803	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1