Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 27 studies | 39% ± 18% | |
pericyte | 23 studies | 34% ± 17% | |
smooth muscle cell | 17 studies | 32% ± 13% | |
oligodendrocyte | 16 studies | 44% ± 19% | |
glutamatergic neuron | 13 studies | 56% ± 26% | |
oligodendrocyte precursor cell | 13 studies | 45% ± 18% | |
microglial cell | 13 studies | 39% ± 13% | |
astrocyte | 12 studies | 41% ± 16% | |
GABAergic neuron | 10 studies | 51% ± 26% | |
macrophage | 10 studies | 37% ± 18% | |
fibroblast | 10 studies | 25% ± 7% | |
endothelial cell of lymphatic vessel | 9 studies | 31% ± 17% | |
adipocyte | 9 studies | 32% ± 9% | |
B cell | 7 studies | 24% ± 9% | |
neuron | 7 studies | 43% ± 15% | |
epithelial cell | 7 studies | 29% ± 15% | |
interneuron | 7 studies | 54% ± 25% | |
plasmacytoid dendritic cell | 7 studies | 27% ± 6% | |
T cell | 7 studies | 20% ± 4% | |
naive B cell | 6 studies | 20% ± 2% | |
retina horizontal cell | 6 studies | 28% ± 14% | |
myeloid cell | 6 studies | 20% ± 4% | |
retinal ganglion cell | 5 studies | 32% ± 19% | |
capillary endothelial cell | 5 studies | 20% ± 4% | |
amacrine cell | 5 studies | 31% ± 9% | |
endothelial cell of vascular tree | 5 studies | 32% ± 20% | |
monocyte | 5 studies | 27% ± 12% | |
natural killer cell | 5 studies | 33% ± 25% | |
dendritic cell | 5 studies | 22% ± 5% | |
granule cell | 4 studies | 47% ± 10% | |
mucosal invariant T cell | 4 studies | 20% ± 3% | |
CD16-negative, CD56-bright natural killer cell, human | 4 studies | 16% ± 1% | |
CD4-positive, alpha-beta T cell | 4 studies | 22% ± 3% | |
ciliated cell | 4 studies | 22% ± 6% | |
Mueller cell | 4 studies | 27% ± 9% | |
CD8-positive, alpha-beta memory T cell | 4 studies | 30% ± 20% | |
club cell | 4 studies | 24% ± 9% | |
type I pneumocyte | 4 studies | 28% ± 8% | |
type II pneumocyte | 4 studies | 22% ± 7% | |
basal cell | 4 studies | 30% ± 17% | |
goblet cell | 4 studies | 36% ± 26% | |
mesothelial cell | 4 studies | 36% ± 16% | |
differentiation-committed oligodendrocyte precursor | 3 studies | 47% ± 13% | |
GABAergic interneuron | 3 studies | 53% ± 3% | |
glial cell | 3 studies | 26% ± 9% | |
progenitor cell | 3 studies | 32% ± 9% | |
CD16-positive, CD56-dim natural killer cell, human | 3 studies | 17% ± 2% | |
precursor B cell | 3 studies | 22% ± 3% | |
pro-B cell | 3 studies | 22% ± 1% | |
cardiac muscle cell | 3 studies | 20% ± 1% | |
vein endothelial cell | 3 studies | 38% ± 18% | |
GABAergic amacrine cell | 3 studies | 32% ± 14% | |
glycinergic amacrine cell | 3 studies | 26% ± 5% | |
retinal rod cell | 3 studies | 25% ± 7% | |
CD8-positive, alpha-beta T cell | 3 studies | 32% ± 13% | |
mast cell | 3 studies | 35% ± 21% | |
myofibroblast cell | 3 studies | 28% ± 7% | |
hepatocyte | 3 studies | 42% ± 19% | |
abnormal cell | 3 studies | 24% ± 10% | |
connective tissue cell | 3 studies | 20% ± 4% | |
ependymal cell | 3 studies | 37% ± 17% | |
alveolar macrophage | 3 studies | 28% ± 10% | |
group 3 innate lymphoid cell | 3 studies | 33% ± 3% | |
lymphocyte | 3 studies | 32% ± 18% | |
leukocyte | 3 studies | 36% ± 13% | |
mural cell | 3 studies | 41% ± 8% | |
mucus secreting cell | 3 studies | 25% ± 4% | |
enteroendocrine cell | 3 studies | 18% ± 2% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
bladder | 100% | 5695.90 | 21 / 21 | 100% | 18.17 | 504 / 504 |
esophagus | 100% | 5468.40 | 1445 / 1445 | 100% | 20.72 | 183 / 183 |
prostate | 100% | 8482.81 | 245 / 245 | 100% | 22.56 | 502 / 502 |
stomach | 100% | 4494.37 | 359 / 359 | 100% | 19.70 | 286 / 286 |
intestine | 100% | 6160.61 | 966 / 966 | 100% | 19.31 | 526 / 527 |
breast | 100% | 10367.71 | 459 / 459 | 100% | 19.42 | 1114 / 1118 |
brain | 100% | 8286.22 | 2631 / 2642 | 100% | 43.63 | 705 / 705 |
lung | 100% | 8020.61 | 578 / 578 | 99% | 15.93 | 1149 / 1155 |
thymus | 100% | 7789.58 | 653 / 653 | 99% | 15.16 | 600 / 605 |
kidney | 100% | 5747.79 | 89 / 89 | 99% | 21.10 | 892 / 901 |
skin | 100% | 7573.83 | 1809 / 1809 | 99% | 20.74 | 467 / 472 |
uterus | 100% | 7423.41 | 170 / 170 | 99% | 16.06 | 454 / 459 |
pancreas | 99% | 3032.04 | 325 / 328 | 99% | 17.51 | 176 / 178 |
ovary | 100% | 6669.37 | 180 / 180 | 96% | 10.62 | 414 / 430 |
adrenal gland | 100% | 5214.12 | 258 / 258 | 92% | 10.32 | 211 / 230 |
liver | 100% | 3491.95 | 226 / 226 | 88% | 8.68 | 359 / 406 |
adipose | 100% | 10807.82 | 1204 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 10260.48 | 1335 / 1335 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 100% | 23.44 | 29 / 29 |
muscle | 100% | 5712.72 | 803 / 803 | 0% | 0 | 0 / 0 |
spleen | 100% | 10079.92 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 13.82 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 5.23 | 1 / 1 |
heart | 100% | 4763.14 | 860 / 861 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 94% | 11.49 | 75 / 80 |
peripheral blood | 74% | 3945.27 | 690 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0048013 | Biological process | ephrin receptor signaling pathway |
GO_2000394 | Biological process | positive regulation of lamellipodium morphogenesis |
GO_0043547 | Biological process | positive regulation of GTPase activity |
GO_0030032 | Biological process | lamellipodium assembly |
GO_0007165 | Biological process | signal transduction |
GO_0010763 | Biological process | positive regulation of fibroblast migration |
GO_1905833 | Biological process | negative regulation of microtubule nucleation |
GO_0007030 | Biological process | Golgi organization |
GO_0048041 | Biological process | focal adhesion assembly |
GO_1900026 | Biological process | positive regulation of substrate adhesion-dependent cell spreading |
GO_0007266 | Biological process | Rho protein signal transduction |
GO_0043065 | Biological process | positive regulation of apoptotic process |
GO_0007399 | Biological process | nervous system development |
GO_0001726 | Cellular component | ruffle |
GO_0097431 | Cellular component | mitotic spindle pole |
GO_0005813 | Cellular component | centrosome |
GO_0032991 | Cellular component | protein-containing complex |
GO_0098794 | Cellular component | postsynapse |
GO_0043025 | Cellular component | neuronal cell body |
GO_0043005 | Cellular component | neuron projection |
GO_0005925 | Cellular component | focal adhesion |
GO_0005829 | Cellular component | cytosol |
GO_0005938 | Cellular component | cell cortex |
GO_0005737 | Cellular component | cytoplasm |
GO_0030027 | Cellular component | lamellipodium |
GO_0043015 | Molecular function | gamma-tubulin binding |
GO_0005085 | Molecular function | guanyl-nucleotide exchange factor activity |
GO_0019901 | Molecular function | protein kinase binding |
GO_0005515 | Molecular function | protein binding |
Gene name | ARHGEF7 |
Protein name | Rho guanine nucleotide exchange factor (GEF) 7, isoform CRA_f (Rho guanine nucleotide exchange factor 7) ARHGEF7 protein Rho guanine nucleotide exchange factor 7 Rho guanine nucleotide exchange factor 7 (Beta-Pix) (COOL-1) (PAK-interacting exchange factor beta) (p85) ARHGEF7 |
Synonyms | hCG_1811466 KIAA0142 PIXB COOL1 Nbla10314 P85SPR PAK3BP |
Description | FUNCTION: Acts as a RAC1 guanine nucleotide exchange factor (GEF) and can induce membrane ruffling. Functions in cell migration, attachment and cell spreading. Promotes targeting of RAC1 to focal adhesions (By similarity). May function as a positive regulator of apoptosis. Downstream of NMDA receptors and CaMKK-CaMK1 signaling cascade, promotes the formation of spines and synapses in hippocampal neurons. . |
Accessions | B1ALK7 ENST00000375741.6 [Q14155-4] A0A8V8TQ72 ENST00000469877.5 C9JDI6 Q14155 E7EUY6 E7ENL8 ENST00000467053.5 ENST00000426073.6 [Q14155-1] ENST00000466143.5 ENST00000375723.5 [Q14155-6] Q5ZEZ2 Q5ZEZ3 ENST00000491775.5 ENST00000375739.6 [Q14155-2] F6SJA5 ENST00000700426.1 ENST00000449979.5 A0A2X0SF98 C9JAD7 ENST00000375736.8 [Q14155-1] ENST00000218789.9 ENST00000317133.9 [Q14155-3] E9PDQ5 ENST00000544132.2 ENST00000478679.5 A0A2R8YG42 ENST00000426768.2 ENST00000646102.2 E7EU80 B1ANY6 |