AQP3 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
CD4-positive, alpha-beta T cell	24 studies	31% ± 12%	Explore
basal cell	23 studies	56% ± 26%	Explore
regulatory T cell	21 studies	34% ± 14%	Explore
ciliated cell	17 studies	45% ± 18%	Explore
epithelial cell	14 studies	54% ± 27%	Explore
plasma cell	13 studies	38% ± 16%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	13 studies	27% ± 8%	Explore
mucosal invariant T cell	12 studies	39% ± 14%	Explore
T cell	12 studies	24% ± 10%	Explore
type II pneumocyte	10 studies	52% ± 24%	Explore
secretory cell	9 studies	69% ± 19%	Explore
plasmablast	8 studies	57% ± 22%	Explore
CD4-positive, alpha-beta memory T cell	8 studies	40% ± 12%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	8 studies	22% ± 5%	Explore
club cell	7 studies	67% ± 19%	Explore
alveolar macrophage	6 studies	30% ± 9%	Explore
ionocyte	6 studies	51% ± 11%	Explore
respiratory goblet cell	6 studies	81% ± 11%	Explore
enterocyte	6 studies	24% ± 6%	Explore
goblet cell	6 studies	25% ± 14%	Explore
effector memory CD4-positive, alpha-beta T cell	6 studies	42% ± 19%	Explore
CD8-positive, alpha-beta memory T cell	5 studies	24% ± 8%	Explore
duct epithelial cell	5 studies	51% ± 15%	Explore
T-helper 17 cell	5 studies	32% ± 18%	Explore
keratinocyte	5 studies	67% ± 22%	Explore
CD4-positive helper T cell	4 studies	22% ± 5%	Explore
deuterosomal cell	4 studies	36% ± 7%	Explore
squamous epithelial cell	4 studies	50% ± 16%	Explore
CD8-positive, alpha-beta T cell	4 studies	43% ± 15%	Explore
group 3 innate lymphoid cell	4 studies	62% ± 16%	Explore
effector CD4-positive, alpha-beta T cell	4 studies	46% ± 21%	Explore
T follicular helper cell	4 studies	23% ± 8%	Explore
type I pneumocyte	3 studies	33% ± 16%	Explore
hillock cell	3 studies	82% ± 18%	Explore
pancreatic D cell	3 studies	59% ± 30%	Explore
renal principal cell	3 studies	76% ± 14%	Explore
mucus secreting cell	3 studies	25% ± 6%	Explore
IgA plasma cell	3 studies	35% ± 16%	Explore
luminal hormone-sensing cell of mammary gland	3 studies	23% ± 1%	Explore
luminal cell of prostate epithelium	3 studies	64% ± 8%	Explore
innate lymphoid cell	3 studies	33% ± 5%	Explore
T-helper 1 cell	3 studies	30% ± 12%	Explore
central memory CD4-positive, alpha-beta T cell	3 studies	40% ± 12%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
lung	9 studies	40% ± 21%	Explore
peripheral blood	5 studies	18% ± 2%	Explore
esophagus	4 studies	48% ± 23%	Explore
prostate	4 studies	41% ± 15%	Explore
skin	3 studies	37% ± 17%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
prostate	79%	9895.71	193 / 245	95%	169.15	478 / 502
kidney	98%	10588.85	87 / 89	60%	84.65	538 / 901
liver	89%	6381.91	202 / 226	53%	64.92	217 / 406
lung	61%	5783.74	355 / 578	74%	413.77	855 / 1155
bladder	57%	12772.67	12 / 21	65%	522.97	327 / 504
esophagus	39%	46387.27	567 / 1445	64%	206.31	117 / 183
ureter	0%	0	0 / 0	100%	203.73	1 / 1
pancreas	25%	1038.36	82 / 328	74%	135.35	132 / 178
spleen	95%	6848.74	228 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	93%	642.55	42 / 45
skin	72%	33517.92	1305 / 1809	12%	33.94	57 / 472
uterus	4%	703.77	7 / 170	73%	747.28	333 / 459
breast	10%	467.10	45 / 459	40%	78.74	449 / 1118
stomach	29%	1388.15	104 / 359	17%	21.57	48 / 286
intestine	11%	783.57	102 / 966	27%	51.37	140 / 527
ovary	10%	411.67	18 / 180	15%	9.77	66 / 430
lymph node	0%	0	0 / 0	21%	16.35	6 / 29
thymus	0%	17.40	3 / 653	14%	55.66	87 / 605
heart	9%	365.73	74 / 861	0%	0	0 / 0
adipose	4%	170.64	44 / 1204	0%	0	0 / 0
adrenal gland	0%	0	0 / 258	3%	3.84	8 / 230
peripheral blood	2%	115.04	18 / 929	0%	0	0 / 0
muscle	1%	30.55	5 / 803	0%	0	0 / 0
blood vessel	1%	36.15	7 / 1335	0%	0	0 / 0
brain	0%	2.01	1 / 2642	0%	0.20	2 / 705
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
eye	0%	0	0 / 0	0%	0	0 / 80
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0071918	Biological process	urea transmembrane transport
GO_0042476	Biological process	odontogenesis
GO_0002931	Biological process	response to ischemia
GO_0003091	Biological process	renal water homeostasis
GO_0015793	Biological process	glycerol transmembrane transport
GO_0033280	Biological process	response to vitamin D
GO_0002684	Biological process	positive regulation of immune system process
GO_0051649	Biological process	establishment of localization in cell
GO_0045616	Biological process	regulation of keratinocyte differentiation
GO_0006833	Biological process	water transport
GO_0070295	Biological process	renal water absorption
GO_0032526	Biological process	response to retinoic acid
GO_0051592	Biological process	response to calcium ion
GO_0071456	Biological process	cellular response to hypoxia
GO_0005886	Cellular component	plasma membrane
GO_0016020	Cellular component	membrane
GO_0005654	Cellular component	nucleoplasm
GO_0005911	Cellular component	cell-cell junction
GO_0005737	Cellular component	cytoplasm
GO_0016323	Cellular component	basolateral plasma membrane
GO_0015250	Molecular function	water channel activity
GO_0015204	Molecular function	urea transmembrane transporter activity
GO_0015254	Molecular function	glycerol channel activity
GO_0042802	Molecular function	identical protein binding
GO_0005515	Molecular function	protein binding

IV. Literature review

[source]

Gene name	AQP3
Protein name	Aquaporin 3 (Gill blood group) Aquaporin-3 (AQP-3) (Aquaglyceroporin-3) Aquaporin-3 (Aquaglyceroporin-3)
Synonyms	hCG_30266
Description	FUNCTION: Water channel required to promote glycerol permeability and water transport across cell membranes . Acts as a glycerol transporter in skin and plays an important role in regulating SC (stratum corneum) and epidermal glycerol content. Involved in skin hydration, wound healing, and tumorigenesis. Provides kidney medullary collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient. Slightly permeable to urea and may function as a water and urea exit mechanism in antidiuresis in collecting duct cells. It may play an important role in gastrointestinal tract water transport and in glycerol metabolism (By similarity). .
Accessions	A0A2R8YD22 Q92482 ENST00000645858.1 ENST00000473153.1 A0A2R8Y2R4 ENST00000297991.6 [Q92482-1] B4E034 A0A2R8YDV4 ENST00000643650.1

AQP3 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review