protein folding in endoplasmic reticulum

I. Literature review

[source]
Nameprotein folding in endoplasmic reticulum
IDGO_0034975
collection_id

Biological process

Exact synonym

oxidative protein folding, protein folding in ER

Description

A protein folding process that takes place in the endoplasmic reticulum (ER). Secreted, plasma membrane and organelle proteins are folded in the ER, assisted by chaperones and foldases (protein disulphide isomerases), and additional factors required for optimal folding (ATP, Ca2+ and an oxidizing environment to allow disulfide bond formation).

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