| Name | eukaryotic 48S preinitiation complex |
| ID | GO_0033290 |
| collection_id | Cellular component |
| Alternative ID | GO:0016283 |
| Exact synonym | eukaryotic 48S pre-initiation complex |
| Description | The protein-ribosome-tRNA complex that has just recognized the start codon of a capped mRNA. It is composed of the small ribosomal subunit, eukaryote initiation factors (eIF) eIF3 complex, eIF1, eIF1A, eIF2-GDP, eIF4 complex and initiatior-methionine-tRNA. Recognition of the start codon triggers downstream steps in the pathway, including eIF1 dissociation; Pi release from eIF2; and conversion to the closed, scanning-arrested conformation of the PIC. |
| Related synonym | eukaryotic 48S initiation complex |
| External URL | |
| Genes |