ZNF106 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
fibroblast	31 studies	28% ± 11%	Explore
macrophage	26 studies	25% ± 10%	Explore
classical monocyte	23 studies	32% ± 13%	Explore
non-classical monocyte	21 studies	34% ± 14%	Explore
monocyte	19 studies	27% ± 7%	Explore
endothelial cell	19 studies	26% ± 9%	Explore
ciliated cell	19 studies	38% ± 13%	Explore
B cell	14 studies	21% ± 4%	Explore
conventional dendritic cell	13 studies	26% ± 12%	Explore
myeloid cell	13 studies	27% ± 10%	Explore
natural killer cell	11 studies	18% ± 3%	Explore
type II pneumocyte	10 studies	21% ± 5%	Explore
epithelial cell	9 studies	34% ± 16%	Explore
plasmacytoid dendritic cell	9 studies	21% ± 5%	Explore
microglial cell	9 studies	29% ± 13%	Explore
dendritic cell	9 studies	30% ± 18%	Explore
type I pneumocyte	8 studies	29% ± 7%	Explore
glutamatergic neuron	8 studies	43% ± 26%	Explore
basal cell	7 studies	25% ± 9%	Explore
CD16-positive, CD56-dim natural killer cell, human	7 studies	18% ± 2%	Explore
astrocyte	7 studies	33% ± 14%	Explore
connective tissue cell	6 studies	20% ± 3%	Explore
retinal rod cell	6 studies	20% ± 4%	Explore
adipocyte	6 studies	23% ± 4%	Explore
pericyte	6 studies	20% ± 3%	Explore
GABAergic neuron	6 studies	40% ± 22%	Explore
smooth muscle cell	5 studies	24% ± 3%	Explore
naive B cell	5 studies	21% ± 3%	Explore
CD16-negative, CD56-bright natural killer cell, human	5 studies	17% ± 2%	Explore
CD8-positive, alpha-beta T cell	5 studies	18% ± 3%	Explore
abnormal cell	5 studies	23% ± 8%	Explore
neuron	5 studies	27% ± 10%	Explore
myofibroblast cell	5 studies	30% ± 11%	Explore
precursor B cell	5 studies	30% ± 3%	Explore
cardiac muscle cell	5 studies	52% ± 11%	Explore
memory B cell	5 studies	19% ± 3%	Explore
oligodendrocyte precursor cell	5 studies	27% ± 8%	Explore
goblet cell	5 studies	24% ± 7%	Explore
T cell	4 studies	17% ± 1%	Explore
deuterosomal cell	4 studies	26% ± 6%	Explore
secretory cell	4 studies	25% ± 11%	Explore
leukocyte	4 studies	24% ± 4%	Explore
lymphocyte	4 studies	20% ± 4%	Explore
retinal cone cell	4 studies	34% ± 10%	Explore
retinal pigment epithelial cell	4 studies	39% ± 19%	Explore
mononuclear phagocyte	4 studies	28% ± 12%	Explore
CD8-positive, alpha-beta memory T cell	4 studies	19% ± 3%	Explore
interneuron	4 studies	42% ± 21%	Explore
oligodendrocyte	4 studies	29% ± 5%	Explore
regulatory T cell	4 studies	16% ± 2%	Explore
endothelial cell of lymphatic vessel	3 studies	16% ± 0%	Explore
CD4-positive, alpha-beta memory T cell	3 studies	18% ± 1%	Explore
respiratory goblet cell	3 studies	25% ± 8%	Explore
plasmablast	3 studies	29% ± 6%	Explore
CD4-positive, alpha-beta T cell	3 studies	19% ± 2%	Explore
hematopoietic precursor cell	3 studies	21% ± 5%	Explore
mature NK T cell	3 studies	16% ± 1%	Explore
retinal ganglion cell	3 studies	44% ± 15%	Explore
brush cell	3 studies	29% ± 8%	Explore
club cell	3 studies	28% ± 8%	Explore
immature B cell	3 studies	28% ± 15%	Explore
amacrine cell	3 studies	28% ± 10%	Explore
germinal center B cell	3 studies	28% ± 5%	Explore
endothelial cell of vascular tree	3 studies	18% ± 2%	Explore
intermediate monocyte	3 studies	44% ± 23%	Explore
mesothelial cell	3 studies	20% ± 2%	Explore
enteroendocrine cell	3 studies	20% ± 3%	Explore
adventitial cell	3 studies	24% ± 6%	Explore
alveolar macrophage	3 studies	25% ± 7%	Explore
gamma-delta T cell	3 studies	25% ± 11%	Explore
transit amplifying cell	3 studies	25% ± 10%	Explore
neutrophil	3 studies	19% ± 3%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
peripheral blood	14 studies	22% ± 7%	Explore
brain	11 studies	35% ± 18%	Explore
lung	9 studies	27% ± 9%	Explore
intestine	5 studies	22% ± 6%	Explore
eye	5 studies	27% ± 6%	Explore
heart	5 studies	28% ± 9%	Explore
adipose	4 studies	21% ± 2%	Explore
bone marrow	3 studies	18% ± 1%	Explore
liver	3 studies	24% ± 6%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	99%	13587.07	1429 / 1445	100%	24.36	183 / 183
brain	99%	6074.93	2615 / 2642	100%	32.90	704 / 705
prostate	100%	5938.96	244 / 245	99%	28.99	497 / 502
lung	100%	9248.52	576 / 578	98%	19.20	1127 / 1155
intestine	100%	7912.64	965 / 966	97%	16.42	510 / 527
breast	98%	6916.38	450 / 459	97%	25.43	1084 / 1118
thymus	97%	3897.41	633 / 653	97%	21.27	588 / 605
uterus	99%	6825.23	169 / 170	94%	17.23	432 / 459
skin	94%	6232.31	1701 / 1809	99%	117.47	466 / 472
stomach	94%	5045.51	337 / 359	97%	19.05	277 / 286
adrenal gland	98%	5074.06	254 / 258	90%	13.21	206 / 230
bladder	100%	7075.29	21 / 21	87%	12.87	436 / 504
kidney	91%	3196.34	81 / 89	92%	20.13	831 / 901
ovary	100%	5187.13	180 / 180	82%	10.07	351 / 430
pancreas	58%	1708.21	191 / 328	95%	15.02	169 / 178
eye	0%	0	0 / 0	100%	135.28	80 / 80
lymph node	0%	0	0 / 0	100%	18.95	29 / 29
muscle	100%	84468.55	803 / 803	0%	0	0 / 0
spleen	100%	5904.79	241 / 241	0%	0	0 / 0
adipose	100%	7935.64	1202 / 1204	0%	0	0 / 0
blood vessel	100%	7468.90	1330 / 1335	0%	0	0 / 0
heart	99%	33269.14	850 / 861	0%	0	0 / 0
liver	35%	958.84	78 / 226	64%	6.27	258 / 406
tonsil	0%	0	0 / 0	93%	20.63	42 / 45
peripheral blood	76%	5199.25	706 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

III. Associated gene sets

GO_0008286	Biological process	insulin receptor signaling pathway
GO_0016607	Cellular component	nuclear speck
GO_0005730	Cellular component	nucleolus
GO_0005829	Cellular component	cytosol
GO_0016020	Cellular component	membrane
GO_0017124	Molecular function	SH3 domain binding
GO_0005515	Molecular function	protein binding
GO_0046872	Molecular function	metal ion binding
GO_0003723	Molecular function	RNA binding

IV. Literature review

[source]

Gene name	ZNF106
Protein name	Zinc finger protein 106 Zinc finger protein 106 (Zfp-106) (Zinc finger protein 474)
Synonyms	ZFP106 ZNF474 hCG_40432 SH3BP3
Description	FUNCTION: RNA-binding protein. Specifically binds to 5'-GGGGCC-3' sequence repeats in RNA. Essential for maintenance of peripheral motor neuron and skeletal muscle function. Required for normal expression and/or alternative splicing of a number of genes in spinal cord and skeletal muscle, including the neurite outgrowth inhibitor RTN4. Also contributes to normal mitochondrial respiratory function in motor neurons, via an unknown mechanism. .
Accessions	ENST00000263805.8 [Q9H2Y7-1] H3BNX5 ENST00000564754.7 H3BS99 ENST00000565380.5 [Q9H2Y7-2] ENST00000567041.1 ENST00000565948.1 ENST00000567772.2 ENST00000565611.5 Q9H2Y7 H3BSS6 A0A0C4DGM5 U3KQH7 H3BRD4 ENST00000565500.5 H3BNJ4 ENST00000569648.5

ZNF106 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review