ZFC3H1 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
endothelial cell	20 studies	27% ± 11%	Explore
B cell	16 studies	24% ± 6%	Explore
natural killer cell	14 studies	22% ± 7%	Explore
fibroblast	14 studies	24% ± 8%	Explore
macrophage	13 studies	32% ± 14%	Explore
classical monocyte	12 studies	22% ± 8%	Explore
CD4-positive, alpha-beta T cell	11 studies	20% ± 6%	Explore
CD8-positive, alpha-beta T cell	11 studies	20% ± 5%	Explore
plasmacytoid dendritic cell	11 studies	22% ± 5%	Explore
naive B cell	10 studies	20% ± 3%	Explore
CD16-negative, CD56-bright natural killer cell, human	10 studies	22% ± 5%	Explore
CD16-positive, CD56-dim natural killer cell, human	10 studies	22% ± 7%	Explore
regulatory T cell	10 studies	20% ± 4%	Explore
oligodendrocyte	10 studies	29% ± 11%	Explore
microglial cell	9 studies	35% ± 11%	Explore
oligodendrocyte precursor cell	9 studies	28% ± 12%	Explore
T cell	8 studies	22% ± 4%	Explore
monocyte	8 studies	28% ± 9%	Explore
non-classical monocyte	8 studies	26% ± 10%	Explore
memory B cell	8 studies	19% ± 2%	Explore
myeloid cell	8 studies	30% ± 8%	Explore
epithelial cell	8 studies	34% ± 20%	Explore
astrocyte	8 studies	29% ± 12%	Explore
mast cell	7 studies	23% ± 7%	Explore
effector memory CD8-positive, alpha-beta T cell	7 studies	21% ± 5%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	7 studies	22% ± 5%	Explore
glutamatergic neuron	7 studies	41% ± 25%	Explore
mucosal invariant T cell	7 studies	19% ± 3%	Explore
adipocyte	7 studies	25% ± 6%	Explore
dendritic cell	7 studies	30% ± 13%	Explore
basal cell	7 studies	26% ± 17%	Explore
GABAergic neuron	7 studies	39% ± 18%	Explore
gamma-delta T cell	7 studies	21% ± 6%	Explore
endothelial cell of lymphatic vessel	6 studies	29% ± 9%	Explore
neuron	6 studies	31% ± 14%	Explore
interneuron	6 studies	39% ± 22%	Explore
pericyte	6 studies	25% ± 7%	Explore
smooth muscle cell	6 studies	23% ± 5%	Explore
CD8-positive, alpha-beta memory T cell	6 studies	21% ± 5%	Explore
type I pneumocyte	5 studies	25% ± 8%	Explore
mature NK T cell	5 studies	21% ± 4%	Explore
ciliated cell	5 studies	20% ± 6%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	4 studies	24% ± 7%	Explore
lymphocyte	4 studies	33% ± 9%	Explore
abnormal cell	4 studies	24% ± 13%	Explore
goblet cell	4 studies	32% ± 25%	Explore
CD4-positive, alpha-beta memory T cell	4 studies	19% ± 3%	Explore
leukocyte	3 studies	25% ± 8%	Explore
conventional dendritic cell	3 studies	38% ± 13%	Explore
plasmablast	3 studies	32% ± 9%	Explore
GABAergic interneuron	3 studies	22% ± 5%	Explore
granule cell	3 studies	20% ± 4%	Explore
plasma cell	3 studies	32% ± 1%	Explore
retina horizontal cell	3 studies	23% ± 7%	Explore
mesothelial cell	3 studies	31% ± 6%	Explore
vein endothelial cell	3 studies	26% ± 12%	Explore
respiratory goblet cell	3 studies	21% ± 5%	Explore
secretory cell	3 studies	17% ± 2%	Explore
effector memory CD4-positive, alpha-beta T cell	3 studies	21% ± 5%	Explore
hepatocyte	3 studies	32% ± 21%	Explore
myofibroblast cell	3 studies	23% ± 8%	Explore
alveolar macrophage	3 studies	37% ± 13%	Explore
type II pneumocyte	3 studies	23% ± 5%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	3 studies	19% ± 3%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
brain	13 studies	32% ± 18%	Explore
peripheral blood	11 studies	21% ± 7%	Explore
lung	6 studies	23% ± 7%	Explore
adipose	4 studies	24% ± 5%	Explore
liver	3 studies	27% ± 15%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	4845.72	1445 / 1445	100%	22.11	183 / 183
bladder	100%	5139.71	21 / 21	100%	15.56	502 / 504
breast	100%	4189.40	459 / 459	99%	17.62	1112 / 1118
lung	100%	6826.13	578 / 578	99%	14.34	1146 / 1155
prostate	100%	4691.32	245 / 245	99%	13.07	497 / 502
uterus	100%	5582.01	170 / 170	98%	15.92	452 / 459
pancreas	99%	2559.33	326 / 328	99%	16.20	176 / 178
stomach	100%	4039.65	359 / 359	98%	16.09	281 / 286
intestine	100%	5456.82	966 / 966	98%	15.42	517 / 527
thymus	100%	5480.09	653 / 653	98%	15.17	593 / 605
ovary	100%	5872.16	180 / 180	98%	9.65	420 / 430
brain	97%	2724.44	2563 / 2642	99%	12.91	701 / 705
kidney	100%	3310.30	89 / 89	96%	12.46	864 / 901
adrenal gland	100%	3773.40	258 / 258	95%	9.34	218 / 230
skin	100%	5208.35	1809 / 1809	92%	13.93	433 / 472
liver	98%	1512.52	222 / 226	73%	5.78	296 / 406
blood vessel	100%	5833.11	1335 / 1335	0%	0	0 / 0
lymph node	0%	0	0 / 0	100%	19.53	29 / 29
spleen	100%	6091.36	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	15.21	45 / 45
ureter	0%	0	0 / 0	100%	6.55	1 / 1
adipose	100%	4252.01	1203 / 1204	0%	0	0 / 0
muscle	99%	2258.17	791 / 803	0%	0	0 / 0
heart	98%	2562.39	840 / 861	0%	0	0 / 0
peripheral blood	87%	2943.85	810 / 929	0%	0	0 / 0
eye	0%	0	0 / 0	63%	5.85	50 / 80
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0006396	Biological process	RNA processing
GO_0005730	Cellular component	nucleolus
GO_0005615	Cellular component	extracellular space
GO_0000178	Cellular component	exosome (RNase complex)
GO_0005634	Cellular component	nucleus
GO_0005515	Molecular function	protein binding
GO_0046872	Molecular function	metal ion binding

IV. Literature review

[source]

Gene name	ZFC3H1
Protein name	Proline/serine-rich coiled-coil 2, isoform CRA_a (Zinc finger C3H1-type containing) Zinc finger C3H1 domain-containing protein (Coiled-coil domain-containing protein 131) (Proline/serine-rich coiled-coil protein 2)
Synonyms	PSRC2 KIAA0546 hCG_25411 CCDC131
Description	FUNCTION: Subunit of the trimeric poly(A) tail exosome targeting (PAXT) complex, a complex that directs a subset of long and polyadenylated poly(A) RNAs for exosomal degradation. The RNA exosome is fundamental for the degradation of RNA in eukaryotic nuclei. Substrate targeting is facilitated by its cofactor MTREX, which links to RNA-binding protein adapters. .
Accessions	O60293 G3V1X1 ENST00000378743.9 [O60293-1] ENST00000548100.1 [O60293-4] ENST00000552037.1 ENST00000552994.5 [O60293-2]

ZFC3H1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review