TUBA1C | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
macrophage	25 studies	31% ± 13%	Explore
basal cell	21 studies	40% ± 14%	Explore
epithelial cell	19 studies	39% ± 19%	Explore
fibroblast	19 studies	33% ± 14%	Explore
endothelial cell	18 studies	24% ± 6%	Explore
conventional dendritic cell	16 studies	28% ± 13%	Explore
smooth muscle cell	16 studies	29% ± 14%	Explore
dendritic cell	15 studies	39% ± 15%	Explore
pericyte	12 studies	35% ± 12%	Explore
T cell	11 studies	23% ± 6%	Explore
secretory cell	10 studies	37% ± 16%	Explore
connective tissue cell	10 studies	26% ± 16%	Explore
CD8-positive, alpha-beta T cell	10 studies	36% ± 21%	Explore
monocyte	9 studies	25% ± 8%	Explore
CD4-positive, alpha-beta T cell	9 studies	40% ± 25%	Explore
type I pneumocyte	8 studies	32% ± 13%	Explore
type II pneumocyte	8 studies	30% ± 12%	Explore
platelet	8 studies	37% ± 14%	Explore
classical monocyte	8 studies	31% ± 12%	Explore
abnormal cell	8 studies	31% ± 10%	Explore
goblet cell	8 studies	23% ± 6%	Explore
myeloid cell	8 studies	34% ± 12%	Explore
endothelial cell of vascular tree	8 studies	27% ± 7%	Explore
enterocyte	7 studies	25% ± 6%	Explore
plasmacytoid dendritic cell	7 studies	21% ± 5%	Explore
ciliated cell	7 studies	33% ± 20%	Explore
regulatory T cell	7 studies	32% ± 20%	Explore
alveolar macrophage	6 studies	21% ± 2%	Explore
non-classical monocyte	6 studies	27% ± 12%	Explore
progenitor cell	6 studies	24% ± 8%	Explore
megakaryocyte	6 studies	65% ± 19%	Explore
natural killer cell	6 studies	30% ± 16%	Explore
CD8-positive, alpha-beta memory T cell	6 studies	22% ± 8%	Explore
endothelial cell of lymphatic vessel	5 studies	30% ± 8%	Explore
B cell	5 studies	21% ± 4%	Explore
hematopoietic precursor cell	5 studies	29% ± 6%	Explore
plasmablast	5 studies	37% ± 17%	Explore
club cell	5 studies	30% ± 12%	Explore
vein endothelial cell	5 studies	25% ± 11%	Explore
transit amplifying cell	5 studies	31% ± 11%	Explore
erythroblast	5 studies	37% ± 15%	Explore
hematopoietic stem cell	5 studies	34% ± 10%	Explore
mast cell	5 studies	21% ± 3%	Explore
astrocyte	5 studies	31% ± 11%	Explore
gamma-delta T cell	5 studies	26% ± 14%	Explore
respiratory goblet cell	4 studies	32% ± 17%	Explore
pancreatic A cell	4 studies	23% ± 10%	Explore
mononuclear phagocyte	4 studies	23% ± 6%	Explore
epithelial cell of proximal tubule	4 studies	21% ± 8%	Explore
myofibroblast cell	4 studies	24% ± 7%	Explore
endothelial cell of artery	4 studies	20% ± 8%	Explore
mucosal invariant T cell	4 studies	20% ± 3%	Explore
neuron	4 studies	42% ± 30%	Explore
retinal pigment epithelial cell	4 studies	43% ± 18%	Explore
adventitial cell	4 studies	22% ± 2%	Explore
erythrocyte	4 studies	43% ± 21%	Explore
effector memory CD4-positive, alpha-beta T cell	4 studies	29% ± 9%	Explore
effector memory CD8-positive, alpha-beta T cell	4 studies	18% ± 2%	Explore
effector CD8-positive, alpha-beta T cell	4 studies	41% ± 20%	Explore
leukocyte	4 studies	27% ± 12%	Explore
CD4-positive, alpha-beta memory T cell	4 studies	29% ± 10%	Explore
duct epithelial cell	3 studies	20% ± 6%	Explore
ionocyte	3 studies	22% ± 4%	Explore
precursor cell	3 studies	69% ± 8%	Explore
kidney distal convoluted tubule epithelial cell	3 studies	26% ± 11%	Explore
renal alpha-intercalated cell	3 studies	25% ± 6%	Explore
kidney loop of Henle epithelial cell	3 studies	25% ± 8%	Explore
extravillous trophoblast	3 studies	85% ± 8%	Explore
placental villous trophoblast	3 studies	54% ± 4%	Explore
lymphocyte	3 studies	33% ± 11%	Explore
plasma cell	3 studies	36% ± 24%	Explore
CD16-negative, CD56-bright natural killer cell, human	3 studies	27% ± 9%	Explore
mesothelial cell	3 studies	25% ± 12%	Explore
intermediate monocyte	3 studies	34% ± 11%	Explore
luminal hormone-sensing cell of mammary gland	3 studies	41% ± 15%	Explore
pancreatic ductal cell	3 studies	69% ± 11%	Explore
megakaryocyte-erythroid progenitor cell	3 studies	47% ± 20%	Explore
keratinocyte	3 studies	42% ± 16%	Explore
glutamatergic neuron	3 studies	24% ± 3%	Explore
effector CD4-positive, alpha-beta T cell	3 studies	32% ± 5%	Explore
progenitor cell of mammary luminal epithelium	3 studies	35% ± 10%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
lung	14 studies	26% ± 15%	Explore
kidney	7 studies	19% ± 4%	Explore
intestine	7 studies	22% ± 4%	Explore
liver	5 studies	31% ± 14%	Explore
pancreas	4 studies	31% ± 6%	Explore
bone marrow	4 studies	18% ± 3%	Explore
uterus	4 studies	32% ± 11%	Explore
prostate	4 studies	34% ± 9%	Explore
breast	4 studies	29% ± 9%	Explore
brain	4 studies	20% ± 7%	Explore
peripheral blood	3 studies	30% ± 10%	Explore
placenta	3 studies	59% ± 6%	Explore
esophagus	3 studies	41% ± 10%	Explore
thymus	3 studies	27% ± 7%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
skin	100%	6310.54	1809 / 1809	97%	61.36	457 / 472
esophagus	97%	5438.70	1397 / 1445	100%	150.65	183 / 183
stomach	97%	2256.33	348 / 359	100%	114.74	285 / 286
breast	98%	1619.65	449 / 459	97%	54.72	1080 / 1118
intestine	94%	2272.79	910 / 966	99%	97.34	522 / 527
lung	94%	2168.73	541 / 578	99%	98.97	1140 / 1155
kidney	100%	2330.73	89 / 89	89%	37.49	803 / 901
bladder	90%	1943.90	19 / 21	97%	85.33	488 / 504
ovary	86%	1055.47	154 / 180	100%	130.43	430 / 430
thymus	96%	1692.66	624 / 653	83%	21.42	503 / 605
uterus	81%	1240.71	137 / 170	98%	96.05	450 / 459
pancreas	67%	685.19	219 / 328	93%	44.23	166 / 178
prostate	86%	1168.77	211 / 245	70%	18.86	349 / 502
adrenal gland	97%	1619.44	250 / 258	37%	10.21	85 / 230
tonsil	0%	0	0 / 0	100%	132.45	45 / 45
ureter	0%	0	0 / 0	100%	27.09	1 / 1
blood vessel	99%	2427.30	1319 / 1335	0%	0	0 / 0
adipose	98%	2097.78	1177 / 1204	0%	0	0 / 0
liver	50%	871.68	113 / 226	45%	14.74	183 / 406
eye	0%	0	0 / 0	91%	30.37	73 / 80
spleen	90%	1078.30	216 / 241	0%	0	0 / 0
lymph node	0%	0	0 / 0	86%	42.20	25 / 29
heart	70%	1105.11	601 / 861	0%	0	0 / 0
peripheral blood	65%	1801.32	600 / 929	0%	0	0 / 0
muscle	64%	731.08	516 / 803	0%	0	0 / 0
brain	17%	159.59	459 / 2642	34%	19.15	241 / 705
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0007017	Biological process	microtubule-based process
GO_0051301	Biological process	cell division
GO_0000278	Biological process	mitotic cell cycle
GO_0030705	Biological process	cytoskeleton-dependent intracellular transport
GO_0000226	Biological process	microtubule cytoskeleton organization
GO_0045121	Cellular component	membrane raft
GO_0015630	Cellular component	microtubule cytoskeleton
GO_0005881	Cellular component	cytoplasmic microtubule
GO_0005874	Cellular component	microtubule
GO_0031982	Cellular component	vesicle
GO_0005737	Cellular component	cytoplasm
GO_0005634	Cellular component	nucleus
GO_0005525	Molecular function	GTP binding
GO_0005200	Molecular function	structural constituent of cytoskeleton
GO_0005198	Molecular function	structural molecule activity
GO_0016787	Molecular function	hydrolase activity
GO_0005515	Molecular function	protein binding
GO_0046872	Molecular function	metal ion binding

IV. Literature review

[source]

Gene name	TUBA1C
Protein name	Tubulin alpha-1B chain Tubulin alpha-1C chain (EC 3.6.5.-) (Alpha-tubulin 6) (Tubulin alpha-6 chain) [Cleaved into: Detyrosinated tubulin alpha-1C chain] TUBA1C protein Tubulin alpha 1c Tubulin alpha chain
Synonyms	TUBA6
Description	FUNCTION: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin. FUNCTION: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin. .
Accessions	H0YHV2 ENST00000552448.1 ENST00000552125.1 F5H5D3 ENST00000541364.5 ENST00000549183.1 ENST00000301072.11 Q9BQE3 F8VRK1 ENST00000549818.5 Q8N532 F8VS66

TUBA1C report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review