TTC1 report

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I. Expression across cell types

Cell ontologyData table

Name	Number of supported studies	Average coverage
natural killer cell	13 studies	18% ± 2%	Explore
endothelial cell	12 studies	29% ± 9%	Explore
macrophage	10 studies	22% ± 8%	Explore
B cell	8 studies	20% ± 7%	Explore
CD8-positive, alpha-beta T cell	7 studies	17% ± 2%	Explore
glutamatergic neuron	7 studies	43% ± 26%	Explore
fibroblast	7 studies	23% ± 10%	Explore
epithelial cell	7 studies	39% ± 15%	Explore
astrocyte	7 studies	30% ± 6%	Explore
ciliated cell	7 studies	30% ± 11%	Explore
endothelial cell of lymphatic vessel	7 studies	19% ± 6%	Explore
GABAergic neuron	7 studies	37% ± 21%	Explore
oligodendrocyte	7 studies	31% ± 10%	Explore
abnormal cell	6 studies	26% ± 8%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	5 studies	17% ± 1%	Explore
non-classical monocyte	5 studies	23% ± 6%	Explore
CD4-positive, alpha-beta T cell	5 studies	19% ± 3%	Explore
conventional dendritic cell	5 studies	28% ± 14%	Explore
smooth muscle cell	5 studies	20% ± 5%	Explore
retina horizontal cell	5 studies	23% ± 5%	Explore
retinal cone cell	5 studies	31% ± 11%	Explore
monocyte	5 studies	21% ± 4%	Explore
regulatory T cell	5 studies	19% ± 3%	Explore
oligodendrocyte precursor cell	5 studies	31% ± 9%	Explore
gamma-delta T cell	5 studies	29% ± 14%	Explore
interneuron	5 studies	37% ± 20%	Explore
pancreatic A cell	4 studies	25% ± 5%	Explore
effector CD8-positive, alpha-beta T cell	4 studies	18% ± 0%	Explore
naive B cell	4 studies	18% ± 2%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	4 studies	20% ± 2%	Explore
CD16-negative, CD56-bright natural killer cell, human	4 studies	20% ± 3%	Explore
CD16-positive, CD56-dim natural killer cell, human	4 studies	19% ± 3%	Explore
classical monocyte	4 studies	23% ± 10%	Explore
effector memory CD8-positive, alpha-beta T cell	4 studies	19% ± 3%	Explore
hematopoietic precursor cell	4 studies	25% ± 9%	Explore
capillary endothelial cell	4 studies	16% ± 1%	Explore
neuron	4 studies	36% ± 11%	Explore
pericyte	4 studies	20% ± 3%	Explore
myeloid cell	4 studies	23% ± 7%	Explore
retinal rod cell	4 studies	22% ± 3%	Explore
erythroblast	4 studies	28% ± 14%	Explore
adipocyte	4 studies	20% ± 4%	Explore
endothelial cell of vascular tree	4 studies	17% ± 2%	Explore
type I pneumocyte	4 studies	22% ± 6%	Explore
goblet cell	4 studies	20% ± 2%	Explore
basal cell	4 studies	32% ± 9%	Explore
plasmacytoid dendritic cell	4 studies	20% ± 5%	Explore
type B pancreatic cell	3 studies	32% ± 7%	Explore
leukocyte	3 studies	21% ± 6%	Explore
retinal ganglion cell	3 studies	60% ± 18%	Explore
precursor B cell	3 studies	18% ± 1%	Explore
amacrine cell	3 studies	27% ± 8%	Explore
retinal bipolar neuron	3 studies	24% ± 3%	Explore
Mueller cell	3 studies	30% ± 5%	Explore
OFF-bipolar cell	3 studies	23% ± 11%	Explore
rod bipolar cell	3 studies	24% ± 6%	Explore
type II pneumocyte	3 studies	24% ± 11%	Explore
microglial cell	3 studies	23% ± 7%	Explore
pancreatic ductal cell	3 studies	35% ± 14%	Explore
granulocyte monocyte progenitor cell	3 studies	23% ± 10%	Explore
enteroendocrine cell	3 studies	22% ± 6%	Explore
intestinal crypt stem cell	3 studies	20% ± 2%	Explore
CD8-positive, alpha-beta memory T cell	3 studies	18% ± 4%	Explore
transit amplifying cell	3 studies	22% ± 7%	Explore
mast cell	3 studies	18% ± 1%	Explore
memory B cell	3 studies	18% ± 1%	Explore

II. Expression across tissues

sc-RNAseq dataData table

Name	Number of supported studies	Average coverage
brain	9 studies	36% ± 18%	Explore
lung	8 studies	22% ± 6%	Explore
peripheral blood	6 studies	21% ± 5%	Explore
eye	6 studies	24% ± 6%	Explore
pancreas	3 studies	30% ± 5%	Explore
intestine	3 studies	22% ± 7%	Explore
liver	3 studies	33% ± 13%	Explore

Bulk RNAseq dataData table

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
brain	100%	3561.69	2642 / 2642	100%	108.14	705 / 705
breast	100%	2097.05	459 / 459	100%	96.27	1118 / 1118
esophagus	100%	2456.86	1445 / 1445	100%	54.89	183 / 183
intestine	100%	2505.42	966 / 966	100%	79.39	527 / 527
kidney	100%	2214.28	89 / 89	100%	96.19	901 / 901
liver	100%	1423.35	226 / 226	100%	66.33	406 / 406
ovary	100%	1736.98	180 / 180	100%	87.54	430 / 430
prostate	100%	2035.31	245 / 245	100%	84.03	502 / 502
stomach	100%	1791.53	359 / 359	100%	71.45	286 / 286
uterus	100%	2092.76	170 / 170	100%	89.83	459 / 459
skin	100%	2296.63	1808 / 1809	100%	87.62	472 / 472
thymus	100%	1853.08	652 / 653	100%	95.35	604 / 605
bladder	100%	2214.57	21 / 21	99%	74.35	501 / 504
lung	99%	1886.48	573 / 578	100%	72.27	1155 / 1155
adrenal gland	100%	2927.88	258 / 258	99%	95.25	228 / 230
pancreas	97%	982.56	319 / 328	100%	71.15	178 / 178
adipose	100%	2211.44	1204 / 1204	0%	0	0 / 0
eye	0%	0	0 / 0	100%	61.35	80 / 80
lymph node	0%	0	0 / 0	100%	144.22	29 / 29
muscle	100%	3153.60	803 / 803	0%	0	0 / 0
spleen	100%	2363.39	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	86.39	45 / 45
ureter	0%	0	0 / 0	100%	19.14	1 / 1
blood vessel	100%	2689.71	1334 / 1335	0%	0	0 / 0
heart	99%	3108.98	854 / 861	0%	0	0 / 0
peripheral blood	95%	2081.70	884 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0