TPP2 report

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I. Expression across cell types

Cell ontologyData table

Name	Number of supported studies	Average coverage
natural killer cell	14 studies	20% ± 3%	Explore
endothelial cell	13 studies	27% ± 11%	Explore
CD16-negative, CD56-bright natural killer cell, human	10 studies	19% ± 3%	Explore
macrophage	10 studies	32% ± 12%	Explore
CD16-positive, CD56-dim natural killer cell, human	9 studies	20% ± 4%	Explore
CD8-positive, alpha-beta T cell	9 studies	20% ± 5%	Explore
microglial cell	9 studies	28% ± 10%	Explore
oligodendrocyte precursor cell	9 studies	30% ± 13%	Explore
fibroblast	9 studies	22% ± 8%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	8 studies	19% ± 5%	Explore
oligodendrocyte	8 studies	31% ± 11%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	6 studies	23% ± 8%	Explore
regulatory T cell	6 studies	19% ± 4%	Explore
epithelial cell	6 studies	30% ± 11%	Explore
GABAergic neuron	6 studies	42% ± 18%	Explore
astrocyte	6 studies	31% ± 12%	Explore
non-classical monocyte	5 studies	20% ± 5%	Explore
B cell	5 studies	18% ± 2%	Explore
CD4-positive, alpha-beta T cell	5 studies	26% ± 5%	Explore
effector memory CD8-positive, alpha-beta T cell	5 studies	19% ± 4%	Explore
neuron	5 studies	22% ± 11%	Explore
interneuron	5 studies	43% ± 26%	Explore
myeloid cell	5 studies	23% ± 5%	Explore
ciliated cell	5 studies	24% ± 7%	Explore
T cell	5 studies	22% ± 4%	Explore
gamma-delta T cell	5 studies	24% ± 6%	Explore
plasma cell	4 studies	30% ± 13%	Explore
lymphocyte	4 studies	28% ± 10%	Explore
glutamatergic neuron	4 studies	56% ± 20%	Explore
endothelial cell of lymphatic vessel	4 studies	26% ± 7%	Explore
pericyte	4 studies	24% ± 8%	Explore
smooth muscle cell	4 studies	18% ± 1%	Explore
CD8-positive, alpha-beta memory T cell	4 studies	22% ± 5%	Explore
CD4-positive, alpha-beta memory T cell	4 studies	18% ± 2%	Explore
classical monocyte	3 studies	25% ± 5%	Explore
hematopoietic precursor cell	3 studies	30% ± 10%	Explore
mature NK T cell	3 studies	18% ± 2%	Explore
plasmablast	3 studies	40% ± 13%	Explore
GABAergic interneuron	3 studies	21% ± 4%	Explore
precursor B cell	3 studies	24% ± 4%	Explore
hepatocyte	3 studies	32% ± 21%	Explore
dendritic cell	3 studies	28% ± 8%	Explore
type II pneumocyte	3 studies	20% ± 3%	Explore
basal cell	3 studies	30% ± 17%	Explore
transit amplifying cell	3 studies	32% ± 20%	Explore
mast cell	3 studies	24% ± 2%	Explore
double negative thymocyte	3 studies	23% ± 4%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	3 studies	15% ± 0%	Explore
mucosal invariant T cell	3 studies	19% ± 2%	Explore

II. Expression across tissues

sc-RNAseq dataData table

Name	Number of supported studies	Average coverage
brain	8 studies	39% ± 19%	Explore
peripheral blood	5 studies	24% ± 7%	Explore
lung	4 studies	19% ± 4%	Explore
liver	4 studies	21% ± 6%	Explore

Bulk RNAseq dataData table

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	2694.74	1445 / 1445	100%	23.16	183 / 183
stomach	100%	2474.86	359 / 359	100%	24.68	286 / 286
lung	100%	4014.60	578 / 578	100%	18.76	1153 / 1155
breast	100%	3795.21	459 / 459	100%	25.12	1114 / 1118
ovary	100%	3899.43	180 / 180	100%	13.03	428 / 430
thymus	100%	4382.28	653 / 653	100%	20.13	602 / 605
bladder	100%	3194.52	21 / 21	99%	20.83	501 / 504
intestine	100%	3476.62	966 / 966	99%	24.15	523 / 527
prostate	100%	2924.84	245 / 245	99%	14.73	497 / 502
pancreas	100%	1854.66	327 / 328	99%	18.12	176 / 178
uterus	100%	3889.19	170 / 170	98%	19.20	452 / 459
brain	99%	2128.86	2604 / 2642	100%	22.43	704 / 705
kidney	100%	2172.69	89 / 89	98%	18.17	879 / 901
skin	100%	3552.98	1809 / 1809	97%	22.53	457 / 472
adrenal gland	100%	2302.24	258 / 258	93%	10.77	215 / 230
liver	100%	2386.26	226 / 226	93%	11.18	377 / 406
adipose	100%	3559.23	1204 / 1204	0%	0	0 / 0
lymph node	0%	0	0 / 0	100%	20.88	29 / 29
muscle	100%	4029.42	803 / 803	0%	0	0 / 0
spleen	100%	4423.93	241 / 241	0%	0	0 / 0
blood vessel	100%	3075.75	1334 / 1335	0%	0	0 / 0
tonsil	0%	0	0 / 0	98%	14.39	44 / 45
heart	98%	2149.87	841 / 861	0%	0	0 / 0
eye	0%	0	0 / 0	83%	10.99	66 / 80
peripheral blood	81%	2674.30	756 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1