TNFRSF18 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of TNFRSF18 at tissue level.

III. Associated gene sets

GO_0007165Biological processsignal transduction
GO_0006915Biological processapoptotic process
GO_0042531Biological processpositive regulation of tyrosine phosphorylation of STAT protein
GO_0043066Biological processnegative regulation of apoptotic process
GO_0045785Biological processpositive regulation of cell adhesion
GO_0033209Biological processtumor necrosis factor-mediated signaling pathway
GO_0002687Biological processpositive regulation of leukocyte migration
GO_0009897Cellular componentexternal side of plasma membrane
GO_0005576Cellular componentextracellular region
GO_0005886Cellular componentplasma membrane
GO_0005031Molecular functiontumor necrosis factor receptor activity
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameTNFRSF18
Protein nameTumor necrosis factor receptor superfamily, member 18
TNF receptor superfamily member 18
Tumor necrosis factor receptor superfamily member 18 isoform 4
Tumor necrosis factor receptor superfamily member 18 (Activation-inducible TNFR family receptor) (Glucocorticoid-induced TNFR-related protein) (CD antigen CD357)
SynonymsUNQ319/PRO364
GITR
AITR
DescriptionFUNCTION: Receptor for TNFSF18. Seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. Mediated NF-kappa-B activation via the TRAF2/NIK pathway.

AccessionsENST00000486728.5
ENST00000379265.5 [Q9Y5U5-3]
A8WFP4
J3KT02
Q9Y5U5
ENST00000379268.7 [Q9Y5U5-1]
A0A0R7FDM1
ENST00000328596.10 [Q9Y5U5-2]