TMEM109 report

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I. Expression across cell types

Cell ontologyData table

Name	Number of supported studies	Average coverage
endothelial cell	24 studies	31% ± 12%	Explore
natural killer cell	19 studies	26% ± 9%	Explore
fibroblast	18 studies	26% ± 10%	Explore
CD8-positive, alpha-beta T cell	17 studies	24% ± 6%	Explore
plasmacytoid dendritic cell	16 studies	44% ± 15%	Explore
pericyte	16 studies	24% ± 8%	Explore
conventional dendritic cell	14 studies	28% ± 16%	Explore
CD16-positive, CD56-dim natural killer cell, human	13 studies	23% ± 6%	Explore
endothelial cell of lymphatic vessel	12 studies	30% ± 10%	Explore
CD4-positive, alpha-beta T cell	11 studies	21% ± 4%	Explore
B cell	11 studies	22% ± 6%	Explore
memory B cell	11 studies	22% ± 5%	Explore
CD16-negative, CD56-bright natural killer cell, human	10 studies	25% ± 6%	Explore
capillary endothelial cell	10 studies	31% ± 9%	Explore
mature NK T cell	9 studies	22% ± 6%	Explore
endothelial cell of artery	9 studies	32% ± 8%	Explore
vein endothelial cell	9 studies	25% ± 9%	Explore
mucosal invariant T cell	9 studies	26% ± 4%	Explore
gamma-delta T cell	9 studies	28% ± 5%	Explore
CD8-positive, alpha-beta memory T cell	8 studies	21% ± 5%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	8 studies	20% ± 3%	Explore
connective tissue cell	8 studies	23% ± 6%	Explore
myofibroblast cell	8 studies	23% ± 9%	Explore
naive B cell	8 studies	22% ± 4%	Explore
type I pneumocyte	7 studies	24% ± 9%	Explore
smooth muscle cell	7 studies	26% ± 10%	Explore
dendritic cell	7 studies	39% ± 17%	Explore
T cell	7 studies	20% ± 5%	Explore
endothelial cell of vascular tree	6 studies	28% ± 10%	Explore
macrophage	6 studies	22% ± 5%	Explore
effector memory CD8-positive, alpha-beta T cell	5 studies	29% ± 3%	Explore
plasma cell	5 studies	32% ± 12%	Explore
effector CD8-positive, alpha-beta T cell	5 studies	25% ± 8%	Explore
regulatory T cell	5 studies	21% ± 3%	Explore
non-classical monocyte	4 studies	18% ± 3%	Explore
epithelial cell	4 studies	32% ± 11%	Explore
ciliated cell	4 studies	20% ± 3%	Explore
basal cell	4 studies	31% ± 9%	Explore
CD4-positive, alpha-beta memory T cell	4 studies	18% ± 4%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	4 studies	23% ± 5%	Explore
plasmablast	3 studies	42% ± 12%	Explore
type B pancreatic cell	3 studies	39% ± 14%	Explore
hematopoietic precursor cell	3 studies	32% ± 10%	Explore
glomerular endothelial cell	3 studies	32% ± 5%	Explore
lymphocyte	3 studies	20% ± 4%	Explore
immature B cell	3 studies	25% ± 7%	Explore
precursor B cell	3 studies	25% ± 7%	Explore
myeloid cell	3 studies	26% ± 9%	Explore
abnormal cell	3 studies	28% ± 11%	Explore
exhausted T cell	3 studies	22% ± 5%	Explore
effector memory CD4-positive, alpha-beta T cell	3 studies	20% ± 4%	Explore
double negative thymocyte	3 studies	27% ± 1%	Explore

II. Expression across tissues

sc-RNAseq dataData table

Name	Number of supported studies	Average coverage
peripheral blood	11 studies	19% ± 2%	Explore
lung	5 studies	25% ± 4%	Explore
pancreas	3 studies	33% ± 10%	Explore
lymph node	3 studies	19% ± 5%	Explore

Bulk RNAseq dataData table

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
skin	100%	7093.43	1809 / 1809	100%	258.92	471 / 472
uterus	100%	10947.96	170 / 170	100%	202.95	458 / 459
ovary	100%	8332.72	180 / 180	100%	142.92	429 / 430
intestine	100%	6862.12	965 / 966	100%	156.47	526 / 527
thymus	100%	7122.87	653 / 653	100%	172.90	603 / 605
lung	100%	8402.04	578 / 578	100%	201.72	1151 / 1155
breast	100%	8628.89	459 / 459	100%	224.78	1114 / 1118
prostate	100%	6542.64	245 / 245	100%	204.13	500 / 502
esophagus	100%	9287.98	1445 / 1445	99%	169.03	182 / 183
kidney	100%	5208.81	89 / 89	99%	197.73	896 / 901
stomach	100%	5499.52	359 / 359	99%	150.28	284 / 286
bladder	100%	8125.95	21 / 21	98%	182.82	495 / 504
pancreas	98%	3015.35	320 / 328	99%	183.87	177 / 178
adrenal gland	100%	5163.26	258 / 258	97%	154.80	223 / 230
liver	96%	2011.00	216 / 226	98%	119.07	399 / 406
brain	85%	1811.97	2238 / 2642	99%	86.41	700 / 705
adipose	100%	9106.30	1204 / 1204	0%	0	0 / 0
blood vessel	100%	10925.22	1335 / 1335	0%	0	0 / 0
eye	0%	0	0 / 0	100%	219.38	80 / 80
lymph node	0%	0	0 / 0	100%	209.78	29 / 29
muscle	100%	5430.64	803 / 803	0%	0	0 / 0
spleen	100%	6426.90	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	237.60	45 / 45
ureter	0%	0	0 / 0	100%	73.36	1 / 1
heart	100%	5928.06	860 / 861	0%	0	0 / 0
peripheral blood	67%	2203.02	621 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0