TADA3 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
natural killer cell	21 studies	24% ± 7%	Explore
regulatory T cell	12 studies	23% ± 4%	Explore
B cell	11 studies	19% ± 4%	Explore
CD16-positive, CD56-dim natural killer cell, human	11 studies	29% ± 7%	Explore
CD8-positive, alpha-beta T cell	11 studies	24% ± 6%	Explore
CD16-negative, CD56-bright natural killer cell, human	10 studies	24% ± 5%	Explore
non-classical monocyte	10 studies	29% ± 14%	Explore
gamma-delta T cell	10 studies	22% ± 8%	Explore
fibroblast	9 studies	23% ± 9%	Explore
CD4-positive, alpha-beta T cell	8 studies	22% ± 6%	Explore
smooth muscle cell	8 studies	23% ± 4%	Explore
ciliated cell	7 studies	26% ± 9%	Explore
mature NK T cell	7 studies	22% ± 4%	Explore
CD8-positive, alpha-beta memory T cell	6 studies	22% ± 10%	Explore
classical monocyte	6 studies	22% ± 7%	Explore
myofibroblast cell	6 studies	21% ± 3%	Explore
epithelial cell	6 studies	34% ± 17%	Explore
CD4-positive, alpha-beta memory T cell	5 studies	22% ± 4%	Explore
basal cell	5 studies	26% ± 10%	Explore
effector memory CD8-positive, alpha-beta T cell	5 studies	21% ± 1%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	5 studies	17% ± 2%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	5 studies	19% ± 2%	Explore
mucosal invariant T cell	5 studies	17% ± 1%	Explore
pericyte	5 studies	22% ± 7%	Explore
T cell	5 studies	22% ± 5%	Explore
plasmacytoid dendritic cell	5 studies	24% ± 5%	Explore
hematopoietic precursor cell	4 studies	23% ± 7%	Explore
conventional dendritic cell	4 studies	33% ± 14%	Explore
exhausted T cell	4 studies	26% ± 7%	Explore
platelet	4 studies	20% ± 6%	Explore
astrocyte	4 studies	24% ± 4%	Explore
endothelial cell	4 studies	22% ± 7%	Explore
T follicular helper cell	4 studies	19% ± 2%	Explore
abnormal cell	4 studies	24% ± 5%	Explore
effector CD4-positive, alpha-beta T cell	4 studies	26% ± 4%	Explore
effector CD8-positive, alpha-beta T cell	4 studies	25% ± 4%	Explore
macrophage	4 studies	20% ± 4%	Explore
effector memory CD4-positive, alpha-beta T cell	4 studies	22% ± 3%	Explore
goblet cell	4 studies	24% ± 4%	Explore
connective tissue cell	3 studies	24% ± 7%	Explore
germinal center B cell	3 studies	22% ± 3%	Explore
naive B cell	3 studies	19% ± 3%	Explore
dendritic cell	3 studies	44% ± 13%	Explore
megakaryocyte	3 studies	35% ± 16%	Explore
megakaryocyte-erythroid progenitor cell	3 studies	35% ± 16%	Explore
double negative thymocyte	3 studies	26% ± 6%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
peripheral blood	9 studies	21% ± 4%	Explore
lung	5 studies	23% ± 6%	Explore
brain	3 studies	22% ± 3%	Explore
intestine	3 studies	24% ± 10%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	4007.39	1445 / 1445	100%	49.17	183 / 183
ovary	100%	5329.71	180 / 180	100%	105.63	430 / 430
prostate	100%	6199.77	245 / 245	100%	131.08	502 / 502
thymus	100%	4843.83	653 / 653	100%	106.58	605 / 605
uterus	100%	5268.34	170 / 170	100%	74.69	459 / 459
skin	100%	3630.33	1808 / 1809	100%	83.28	472 / 472
brain	100%	4386.24	2640 / 2642	100%	103.03	705 / 705
lung	100%	4156.46	578 / 578	100%	59.64	1152 / 1155
kidney	100%	4260.12	89 / 89	100%	61.39	898 / 901
adrenal gland	100%	6679.60	258 / 258	100%	63.61	229 / 230
breast	100%	3948.35	459 / 459	100%	80.70	1113 / 1118
liver	100%	3184.37	226 / 226	100%	44.54	404 / 406
intestine	100%	4672.59	966 / 966	99%	64.67	524 / 527
stomach	100%	3605.10	359 / 359	99%	60.37	284 / 286
bladder	100%	4860.76	21 / 21	99%	81.66	500 / 504
pancreas	98%	1896.91	322 / 328	100%	70.28	178 / 178
adipose	100%	3756.19	1204 / 1204	0%	0	0 / 0
blood vessel	100%	4531.16	1335 / 1335	0%	0	0 / 0
eye	0%	0	0 / 0	100%	54.26	80 / 80
lymph node	0%	0	0 / 0	100%	114.03	29 / 29
muscle	100%	3710.69	803 / 803	0%	0	0 / 0
spleen	100%	4774.17	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	67.99	45 / 45
ureter	0%	0	0 / 0	100%	59.68	1 / 1
heart	99%	3310.14	854 / 861	0%	0	0 / 0
peripheral blood	99%	5474.72	919 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0006325	Biological process	chromatin organization
GO_0045995	Biological process	regulation of embryonic development
GO_0000278	Biological process	mitotic cell cycle
GO_0006357	Biological process	regulation of transcription by RNA polymerase II
GO_0090043	Biological process	regulation of tubulin deacetylation
GO_0006282	Biological process	regulation of DNA repair
GO_0010628	Biological process	positive regulation of gene expression
GO_0001932	Biological process	regulation of protein phosphorylation
GO_0000122	Biological process	negative regulation of transcription by RNA polymerase II
GO_0051302	Biological process	regulation of cell division
GO_0045893	Biological process	positive regulation of DNA-templated transcription
GO_0006355	Biological process	regulation of DNA-templated transcription
GO_0043484	Biological process	regulation of RNA splicing
GO_0030520	Biological process	estrogen receptor signaling pathway
GO_0051726	Biological process	regulation of cell cycle
GO_0031647	Biological process	regulation of protein stability
GO_0072686	Cellular component	mitotic spindle
GO_0005654	Cellular component	nucleoplasm
GO_0033276	Cellular component	transcription factor TFTC complex
GO_0140672	Cellular component	ATAC complex
GO_0000124	Cellular component	SAGA complex
GO_0005634	Cellular component	nucleus
GO_0016922	Molecular function	nuclear receptor binding
GO_0019904	Molecular function	protein domain specific binding
GO_0003713	Molecular function	transcription coactivator activity
GO_0030374	Molecular function	nuclear receptor coactivator activity
GO_0005515	Molecular function	protein binding

IV. Literature review

[source]

Gene name	TADA3
Protein name	Transcriptional adapter 3 (ADA3 homolog) (Transcriptional adapter 3-like) Transcriptional adapter 3 (ADA3 homolog) (hADA3) (STAF54) (Transcriptional adapter 3-like) (ADA3-like protein)
Synonyms	ADA3 TADA3L
Description	FUNCTION: Functions as a component of the PCAF complex. The PCAF complex is capable of efficiently acetylating histones in a nucleosomal context. The PCAF complex could be considered as the human version of the yeast SAGA complex. Also known as a coactivator for p53/TP53-dependent transcriptional activation. Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4. .
Accessions	O75528 ENST00000439043.1 C9JMS0 ENST00000301964.7 [O75528-1] ENST00000440161.5 [O75528-1] ENST00000343450.2 [O75528-2]

TADA3 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review