TACC1 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
endothelial cell	54 studies	57% ± 20%	Explore
fibroblast	41 studies	41% ± 17%	Explore
pericyte	38 studies	55% ± 22%	Explore
smooth muscle cell	33 studies	45% ± 16%	Explore
macrophage	32 studies	31% ± 13%	Explore
natural killer cell	25 studies	22% ± 7%	Explore
mast cell	23 studies	30% ± 12%	Explore
B cell	21 studies	22% ± 6%	Explore
endothelial cell of lymphatic vessel	21 studies	40% ± 14%	Explore
classical monocyte	19 studies	26% ± 11%	Explore
monocyte	17 studies	27% ± 11%	Explore
plasmacytoid dendritic cell	16 studies	40% ± 12%	Explore
non-classical monocyte	16 studies	30% ± 14%	Explore
endothelial cell of artery	16 studies	58% ± 12%	Explore
conventional dendritic cell	16 studies	25% ± 12%	Explore
capillary endothelial cell	16 studies	46% ± 17%	Explore
vein endothelial cell	15 studies	50% ± 17%	Explore
microglial cell	15 studies	38% ± 17%	Explore
dendritic cell	14 studies	31% ± 16%	Explore
CD8-positive, alpha-beta T cell	14 studies	20% ± 6%	Explore
oligodendrocyte	14 studies	44% ± 17%	Explore
endothelial cell of vascular tree	13 studies	49% ± 23%	Explore
CD16-negative, CD56-bright natural killer cell, human	12 studies	21% ± 6%	Explore
myofibroblast cell	12 studies	39% ± 13%	Explore
myeloid cell	12 studies	30% ± 12%	Explore
T cell	11 studies	24% ± 11%	Explore
type I pneumocyte	11 studies	50% ± 15%	Explore
astrocyte	11 studies	37% ± 17%	Explore
type II pneumocyte	10 studies	41% ± 13%	Explore
connective tissue cell	10 studies	32% ± 15%	Explore
CD16-positive, CD56-dim natural killer cell, human	10 studies	24% ± 8%	Explore
glutamatergic neuron	10 studies	51% ± 25%	Explore
regulatory T cell	10 studies	18% ± 2%	Explore
CD4-positive, alpha-beta T cell	9 studies	18% ± 4%	Explore
CD8-positive, alpha-beta memory T cell	8 studies	21% ± 5%	Explore
leukocyte	8 studies	28% ± 6%	Explore
epithelial cell	8 studies	37% ± 15%	Explore
adipocyte	8 studies	53% ± 17%	Explore
gamma-delta T cell	8 studies	25% ± 9%	Explore
mononuclear phagocyte	7 studies	28% ± 9%	Explore
mature NK T cell	7 studies	22% ± 6%	Explore
kidney loop of Henle epithelial cell	7 studies	27% ± 10%	Explore
memory B cell	7 studies	18% ± 3%	Explore
naive B cell	7 studies	22% ± 5%	Explore
basal cell	7 studies	25% ± 15%	Explore
oligodendrocyte precursor cell	7 studies	31% ± 10%	Explore
effector memory CD8-positive, alpha-beta T cell	6 studies	23% ± 8%	Explore
neuron	6 studies	39% ± 21%	Explore
goblet cell	6 studies	36% ± 12%	Explore
amacrine cell	6 studies	24% ± 7%	Explore
innate lymphoid cell	6 studies	21% ± 6%	Explore
mesothelial cell	6 studies	43% ± 18%	Explore
GABAergic neuron	6 studies	46% ± 22%	Explore
kidney distal convoluted tubule epithelial cell	5 studies	40% ± 10%	Explore
mucosal invariant T cell	5 studies	19% ± 3%	Explore
retina horizontal cell	5 studies	26% ± 6%	Explore
retinal pigment epithelial cell	5 studies	56% ± 9%	Explore
adventitial cell	5 studies	43% ± 16%	Explore
squamous epithelial cell	4 studies	34% ± 15%	Explore
cholangiocyte	4 studies	61% ± 20%	Explore
endothelial cell of sinusoid	4 studies	57% ± 13%	Explore
hematopoietic precursor cell	4 studies	31% ± 14%	Explore
glomerular endothelial cell	4 studies	59% ± 15%	Explore
glial cell	4 studies	26% ± 8%	Explore
lymphocyte	4 studies	33% ± 5%	Explore
CD4-positive, alpha-beta memory T cell	4 studies	18% ± 3%	Explore
abnormal cell	4 studies	27% ± 15%	Explore
club cell	4 studies	22% ± 6%	Explore
alveolar macrophage	4 studies	26% ± 9%	Explore
effector CD8-positive, alpha-beta T cell	3 studies	18% ± 3%	Explore
hepatic stellate cell	3 studies	45% ± 19%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	3 studies	19% ± 4%	Explore
GABAergic interneuron	3 studies	21% ± 5%	Explore
megakaryocyte	3 studies	38% ± 12%	Explore
precursor B cell	3 studies	18% ± 2%	Explore
endocardial cell	3 studies	50% ± 16%	Explore
tissue-resident macrophage	3 studies	38% ± 19%	Explore
Mueller cell	3 studies	19% ± 3%	Explore
germinal center B cell	3 studies	25% ± 4%	Explore
hepatocyte	3 studies	38% ± 14%	Explore
granulocyte	3 studies	30% ± 5%	Explore
muscle cell	3 studies	64% ± 10%	Explore
pancreatic A cell	3 studies	38% ± 16%	Explore
pancreatic ductal cell	3 studies	64% ± 19%	Explore
neutrophil	3 studies	21% ± 4%	Explore
group 3 innate lymphoid cell	3 studies	30% ± 11%	Explore
Schwann cell	3 studies	31% ± 3%	Explore
hematopoietic stem cell	3 studies	20% ± 3%	Explore
interneuron	3 studies	59% ± 20%	Explore
myoepithelial cell	3 studies	34% ± 20%	Explore
secretory cell	3 studies	47% ± 19%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
brain	17 studies	40% ± 22%	Explore
lung	13 studies	31% ± 10%	Explore
peripheral blood	9 studies	25% ± 12%	Explore
kidney	7 studies	28% ± 7%	Explore
heart	6 studies	29% ± 9%	Explore
intestine	5 studies	21% ± 6%	Explore
liver	5 studies	30% ± 13%	Explore
uterus	4 studies	34% ± 13%	Explore
placenta	3 studies	24% ± 6%	Explore
bone marrow	3 studies	23% ± 5%	Explore
eye	3 studies	33% ± 11%	Explore
breast	3 studies	25% ± 4%	Explore
adipose	3 studies	37% ± 10%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	25106.29	1439 / 1445	99%	41.37	181 / 183
thymus	100%	14338.76	652 / 653	98%	28.13	592 / 605
lung	100%	21821.60	578 / 578	97%	32.30	1121 / 1155
prostate	100%	14121.09	244 / 245	97%	35.63	489 / 502
intestine	100%	20559.63	964 / 966	97%	33.49	512 / 527
brain	97%	8283.88	2551 / 2642	100%	40.55	703 / 705
bladder	100%	19583.10	21 / 21	93%	28.63	469 / 504
stomach	94%	11054.26	337 / 359	98%	36.47	279 / 286
breast	100%	25584.94	458 / 459	91%	26.81	1012 / 1118
adrenal gland	97%	6737.02	251 / 258	91%	21.42	210 / 230
kidney	93%	7364.69	83 / 89	95%	39.42	857 / 901
pancreas	88%	5914.05	287 / 328	99%	39.66	177 / 178
uterus	100%	26198.52	170 / 170	86%	22.81	394 / 459
skin	87%	7707.23	1569 / 1809	97%	34.31	460 / 472
ovary	100%	11772.05	180 / 180	75%	11.62	321 / 430
adipose	100%	31776.91	1204 / 1204	0%	0	0 / 0
blood vessel	100%	22649.56	1335 / 1335	0%	0	0 / 0
lymph node	0%	0	0 / 0	100%	34.79	29 / 29
spleen	100%	15474.00	241 / 241	0%	0	0 / 0
ureter	0%	0	0 / 0	100%	29.19	1 / 1
liver	20%	897.05	45 / 226	78%	20.36	317 / 406
heart	93%	7675.20	799 / 861	0%	0	0 / 0
eye	0%	0	0 / 0	90%	19.60	72 / 80
tonsil	0%	0	0 / 0	89%	23.73	40 / 45
peripheral blood	55%	7584.16	509 / 929	0%	0	0 / 0
muscle	53%	2856.15	427 / 803	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0008283	Biological process	cell population proliferation
GO_0007052	Biological process	mitotic spindle organization
GO_0051301	Biological process	cell division
GO_0045893	Biological process	positive regulation of DNA-templated transcription
GO_0000226	Biological process	microtubule cytoskeleton organization
GO_0021987	Biological process	cerebral cortex development
GO_0030496	Cellular component	midbody
GO_0016020	Cellular component	membrane
GO_0005813	Cellular component	centrosome
GO_0005829	Cellular component	cytosol
GO_0005737	Cellular component	cytoplasm
GO_0005634	Cellular component	nucleus
GO_0046966	Molecular function	nuclear thyroid hormone receptor binding
GO_0016922	Molecular function	nuclear receptor binding
GO_0035259	Molecular function	nuclear glucocorticoid receptor binding
GO_0030331	Molecular function	nuclear estrogen receptor binding
GO_0046965	Molecular function	nuclear retinoid X receptor binding
GO_0042974	Molecular function	nuclear retinoic acid receptor binding
GO_0042975	Molecular function	peroxisome proliferator activated receptor binding
GO_0030374	Molecular function	nuclear receptor coactivator activity
GO_0005515	Molecular function	protein binding

IV. Literature review

[source]

Gene name	TACC1
Protein name	Transforming, acidic coiled-coil containing protein 1 variant TACC1-B Transforming acidic coiled-coil containing protein 1 Transforming acidic coiled-coil-containing protein 1 (Gastric cancer antigen Ga55) (Taxin-1) Transforming acidic coiled-coil containing protein 1 (cDNA FLJ52297, highly similar to Transforming acidic coiled-coil-containing protein 1)
Synonyms	KIAA1103
Description	FUNCTION: Involved in transcription regulation induced by nuclear receptors, including in T3 thyroid hormone and all-trans retinoic acid pathways . Might promote the nuclear localization of the receptors . Likely involved in the processes that promote cell division prior to the formation of differentiated tissues. .
Accessions	A0A0C4DGD5 ENST00000518415.5 [O75410-7] E7ET87 ENST00000521528.6 ENST00000521866.5 ENST00000518809.5 ENST00000520340.5 H0YAY0 ENST00000522904.6 ENST00000524193.1 ENST00000520615.5 [O75410-3] ENST00000521935.5 E5RIP3 ENST00000317827.9 [O75410-1] E5RJG6 E5RJU4 Q8IUJ5 ENST00000519416.5 ENST00000524354.5 A0A0C4DGD3 ENST00000521642.5 E5RFM9 R4GMT7 H0YBT8 ENST00000520611.1 E7EVI4 B4E3H6 ENST00000520973.5 O75410 ENST00000276520.12 [O75410-6] ENST00000521050.5 E5RI10

TACC1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review