STAG1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0090307Biological processmitotic spindle assembly
GO_0007062Biological processsister chromatid cohesion
GO_0051301Biological processcell division
GO_0034087Biological processestablishment of mitotic sister chromatid cohesion
GO_0000775Cellular componentchromosome, centromeric region
GO_0016363Cellular componentnuclear matrix
GO_0097431Cellular componentmitotic spindle pole
GO_0005694Cellular componentchromosome
GO_0016604Cellular componentnuclear body
GO_0005654Cellular componentnucleoplasm
GO_0005829Cellular componentcytosol
GO_0008278Cellular componentcohesin complex
GO_0000785Cellular componentchromatin
GO_0030892Cellular componentmitotic cohesin complex
GO_0005634Cellular componentnucleus
GO_0005515Molecular functionprotein binding
GO_0003682Molecular functionchromatin binding

IV. Literature review

[source]
Gene nameSTAG1
Protein nameCohesin subunit SA (SCC3 homolog) (Stromal antigen)
Stromal antigen 1
Cohesin subunit SA-1 (SCC3 homolog 1) (Stromal antigen 1)
SynonymsSCC3
protein
SA1
DKFZp781D1416
variant
DescriptionFUNCTION: Component of cohesin complex, a complex required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. The cohesin complex may also play a role in spindle pole assembly during mitosis.

FUNCTION: Component of cohesin complex, a complex required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. .

AccessionsENST00000383202.7 [Q8WVM7-1]
ENST00000480733.1
Q68DW7
ENST00000434713.6
ENST00000236698.9 [Q8WVM7-2]
H7C595
Q4LE48
Q8WVM7
C9JJQ0
F8WF82
ENST00000483235.5
ENST00000492318.1
F8WCB3
ENST00000487065.5
ENST00000629124.2