SP110 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
B cell	35 studies	39% ± 15%	Explore
CD8-positive, alpha-beta T cell	25 studies	24% ± 7%	Explore
natural killer cell	22 studies	25% ± 6%	Explore
CD4-positive, alpha-beta T cell	21 studies	24% ± 7%	Explore
memory B cell	20 studies	42% ± 14%	Explore
naive B cell	20 studies	36% ± 10%	Explore
regulatory T cell	20 studies	26% ± 8%	Explore
non-classical monocyte	19 studies	37% ± 16%	Explore
plasmacytoid dendritic cell	15 studies	37% ± 12%	Explore
T cell	15 studies	23% ± 5%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	15 studies	27% ± 9%	Explore
conventional dendritic cell	14 studies	27% ± 15%	Explore
classical monocyte	14 studies	28% ± 13%	Explore
CD16-positive, CD56-dim natural killer cell, human	13 studies	29% ± 7%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	13 studies	30% ± 11%	Explore
monocyte	12 studies	27% ± 8%	Explore
CD16-negative, CD56-bright natural killer cell, human	12 studies	26% ± 8%	Explore
gamma-delta T cell	12 studies	25% ± 5%	Explore
macrophage	11 studies	22% ± 7%	Explore
CD8-positive, alpha-beta memory T cell	10 studies	26% ± 9%	Explore
mature NK T cell	10 studies	23% ± 7%	Explore
mucosal invariant T cell	10 studies	23% ± 5%	Explore
CD4-positive, alpha-beta memory T cell	9 studies	24% ± 6%	Explore
endothelial cell	9 studies	25% ± 6%	Explore
effector memory CD8-positive, alpha-beta T cell	8 studies	28% ± 9%	Explore
microglial cell	7 studies	33% ± 12%	Explore
effector CD8-positive, alpha-beta T cell	6 studies	25% ± 5%	Explore
leukocyte	6 studies	22% ± 2%	Explore
immature B cell	6 studies	51% ± 11%	Explore
T follicular helper cell	6 studies	25% ± 7%	Explore
dendritic cell	6 studies	35% ± 18%	Explore
precursor B cell	5 studies	36% ± 10%	Explore
myeloid cell	5 studies	21% ± 3%	Explore
plasmablast	4 studies	33% ± 13%	Explore
exhausted T cell	4 studies	33% ± 11%	Explore
lymphocyte	4 studies	25% ± 8%	Explore
basal cell	4 studies	19% ± 1%	Explore
pro-B cell	4 studies	26% ± 4%	Explore
effector CD4-positive, alpha-beta T cell	4 studies	29% ± 9%	Explore
endothelial cell of vascular tree	4 studies	20% ± 5%	Explore
effector memory CD4-positive, alpha-beta T cell	4 studies	27% ± 11%	Explore
innate lymphoid cell	4 studies	20% ± 5%	Explore
hematopoietic stem cell	4 studies	22% ± 3%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	4 studies	24% ± 7%	Explore
epithelial cell	3 studies	21% ± 2%	Explore
endothelial cell of artery	3 studies	20% ± 1%	Explore
germinal center B cell	3 studies	24% ± 2%	Explore
abnormal cell	3 studies	33% ± 10%	Explore
T-helper 17 cell	3 studies	21% ± 1%	Explore
central memory CD4-positive, alpha-beta T cell	3 studies	30% ± 9%	Explore
double negative thymocyte	3 studies	27% ± 8%	Explore
astrocyte	3 studies	29% ± 5%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
peripheral blood	15 studies	30% ± 9%	Explore
lung	4 studies	16% ± 1%	Explore
lymph node	4 studies	26% ± 4%	Explore
brain	3 studies	17% ± 1%	Explore
liver	3 studies	19% ± 4%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	743.22	1441 / 1445	100%	13.50	183 / 183
breast	100%	1312.14	459 / 459	99%	19.14	1105 / 1118
prostate	100%	944.48	244 / 245	99%	9.73	498 / 502
lung	100%	1549.57	578 / 578	98%	12.61	1129 / 1155
skin	100%	858.88	1807 / 1809	97%	15.27	458 / 472
ovary	100%	1190.97	180 / 180	97%	11.17	416 / 430
uterus	100%	1025.61	170 / 170	97%	11.77	443 / 459
thymus	100%	851.92	651 / 653	97%	9.89	585 / 605
stomach	100%	684.24	358 / 359	96%	9.84	274 / 286
kidney	100%	818.43	89 / 89	95%	9.76	852 / 901
intestine	100%	1120.11	966 / 966	93%	8.63	488 / 527
bladder	100%	1000.95	21 / 21	92%	9.99	464 / 504
pancreas	92%	469.21	301 / 328	95%	12.87	169 / 178
liver	91%	417.64	206 / 226	88%	6.15	356 / 406
adrenal gland	99%	730.43	256 / 258	71%	5.01	163 / 230
brain	73%	337.76	1939 / 2642	93%	8.57	657 / 705
adipose	100%	1412.06	1204 / 1204	0%	0	0 / 0
lymph node	0%	0	0 / 0	100%	40.22	29 / 29
peripheral blood	100%	4752.80	929 / 929	0%	0	0 / 0
spleen	100%	3222.90	241 / 241	0%	0	0 / 0
blood vessel	100%	999.87	1334 / 1335	0%	0	0 / 0
tonsil	0%	0	0 / 0	98%	13.10	44 / 45
heart	97%	531.11	834 / 861	0%	0	0 / 0
muscle	83%	339.49	667 / 803	0%	0	0 / 0
eye	0%	0	0 / 0	79%	5.73	63 / 80
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

III. Associated gene sets

GO_0006357	Biological process	regulation of transcription by RNA polymerase II
GO_0005654	Cellular component	nucleoplasm
GO_0005634	Cellular component	nucleus
GO_0003677	Molecular function	DNA binding
GO_0000981	Molecular function	DNA-binding transcription factor activity, RNA polymerase II-specific
GO_0046872	Molecular function	metal ion binding

IV. Literature review

[source]

Gene name	SP110
Protein name	SP110 protein Sp110 nuclear body protein (Interferon-induced protein 41/75) (Speckled 110 kDa) (Transcriptional coactivator Sp110) SP110 nuclear body protein SP110
Synonyms	hCG_32956
Description	FUNCTION: Transcription factor. May be a nuclear hormone receptor coactivator. Enhances transcription of genes with retinoic acid response elements (RARE).
Accessions	Q2I9M1 ENST00000409815.6 ENST00000392048.7 Q2I9M0 ENST00000698100.1 Q6PJR6 A0A8H2SA48 ENST00000258381.11 [Q9HB58-6] E7EM70 A0A8V8TLH4 ENST00000455674.2 ENST00000698103.1 Q2I9M3 G5E9C0 A0A8V8TLE9 Q2I9L9 Q2I9M2 ENST00000540870.5 [Q9HB58-7] A0A8V8TMX7 ENST00000358662.9 [Q9HB58-1] C9JZQ4 ENST00000698099.1 [Q9HB58-1] ENST00000462232.2 ENST00000258382.10 [Q9HB58-3] A0A8V8TN67 ENST00000489597.2 Q9HB58 A0A8F1ACL7

SP110 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review