SERTAD1 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
endothelial cell	27 studies	44% ± 20%	Explore
fibroblast	25 studies	38% ± 17%	Explore
natural killer cell	24 studies	26% ± 9%	Explore
pericyte	19 studies	45% ± 24%	Explore
smooth muscle cell	18 studies	38% ± 18%	Explore
connective tissue cell	14 studies	28% ± 12%	Explore
CD8-positive, alpha-beta T cell	14 studies	22% ± 7%	Explore
macrophage	14 studies	24% ± 7%	Explore
basal cell	14 studies	28% ± 12%	Explore
mast cell	13 studies	24% ± 9%	Explore
B cell	12 studies	23% ± 7%	Explore
conventional dendritic cell	11 studies	30% ± 12%	Explore
classical monocyte	11 studies	22% ± 5%	Explore
CD16-positive, CD56-dim natural killer cell, human	11 studies	30% ± 12%	Explore
capillary endothelial cell	11 studies	32% ± 10%	Explore
endothelial cell of vascular tree	11 studies	45% ± 21%	Explore
gamma-delta T cell	11 studies	28% ± 10%	Explore
T cell	10 studies	26% ± 11%	Explore
mature NK T cell	10 studies	25% ± 9%	Explore
epithelial cell	10 studies	33% ± 18%	Explore
myofibroblast cell	10 studies	36% ± 23%	Explore
endothelial cell of artery	9 studies	33% ± 13%	Explore
CD4-positive, alpha-beta T cell	9 studies	25% ± 10%	Explore
vein endothelial cell	8 studies	32% ± 13%	Explore
endothelial cell of lymphatic vessel	7 studies	34% ± 16%	Explore
innate lymphoid cell	7 studies	28% ± 6%	Explore
CD16-negative, CD56-bright natural killer cell, human	7 studies	33% ± 13%	Explore
naive B cell	7 studies	20% ± 4%	Explore
monocyte	6 studies	25% ± 8%	Explore
effector memory CD8-positive, alpha-beta T cell	6 studies	24% ± 3%	Explore
memory B cell	6 studies	23% ± 7%	Explore
mucosal invariant T cell	6 studies	27% ± 9%	Explore
myeloid cell	6 studies	26% ± 6%	Explore
ciliated cell	6 studies	29% ± 13%	Explore
regulatory T cell	6 studies	21% ± 2%	Explore
type I pneumocyte	5 studies	28% ± 6%	Explore
non-classical monocyte	5 studies	24% ± 4%	Explore
abnormal cell	5 studies	31% ± 13%	Explore
dendritic cell	5 studies	28% ± 12%	Explore
CD8-positive, alpha-beta memory T cell	5 studies	31% ± 9%	Explore
secretory cell	5 studies	32% ± 14%	Explore
leukocyte	4 studies	23% ± 4%	Explore
glomerular endothelial cell	4 studies	29% ± 14%	Explore
plasmacytoid dendritic cell	4 studies	21% ± 4%	Explore
luminal hormone-sensing cell of mammary gland	4 studies	40% ± 15%	Explore
effector CD4-positive, alpha-beta T cell	3 studies	25% ± 7%	Explore
effector CD8-positive, alpha-beta T cell	3 studies	26% ± 4%	Explore
mononuclear phagocyte	3 studies	20% ± 3%	Explore
renal alpha-intercalated cell	3 studies	36% ± 16%	Explore
kidney loop of Henle epithelial cell	3 studies	22% ± 5%	Explore
plasma cell	3 studies	20% ± 4%	Explore
immature B cell	3 studies	31% ± 13%	Explore
type II pneumocyte	3 studies	27% ± 6%	Explore
CD4-positive helper T cell	3 studies	25% ± 7%	Explore
chondrocyte	3 studies	21% ± 4%	Explore
luminal cell of prostate epithelium	3 studies	22% ± 5%	Explore
T follicular helper cell	3 studies	27% ± 1%	Explore
group 3 innate lymphoid cell	3 studies	29% ± 11%	Explore
progenitor cell of mammary luminal epithelium	3 studies	45% ± 18%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
lung	11 studies	22% ± 4%	Explore
peripheral blood	8 studies	20% ± 3%	Explore
intestine	4 studies	29% ± 15%	Explore
kidney	4 studies	31% ± 8%	Explore
uterus	4 studies	42% ± 12%	Explore
breast	4 studies	41% ± 6%	Explore
skin	3 studies	28% ± 10%	Explore
esophagus	3 studies	22% ± 4%	Explore
prostate	3 studies	20% ± 3%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
thymus	100%	1223.92	651 / 653	100%	50.45	604 / 605
uterus	100%	1052.71	170 / 170	99%	56.87	456 / 459
prostate	100%	1115.76	245 / 245	99%	43.76	498 / 502
breast	100%	1070.45	459 / 459	99%	36.65	1108 / 1118
intestine	100%	1133.58	966 / 966	99%	33.17	522 / 527
lung	100%	2189.26	578 / 578	99%	38.23	1142 / 1155
skin	100%	1428.67	1809 / 1809	99%	29.16	466 / 472
bladder	100%	1075.57	21 / 21	99%	42.64	497 / 504
esophagus	100%	1291.49	1445 / 1445	98%	24.67	180 / 183
stomach	100%	1439.62	359 / 359	98%	26.72	280 / 286
kidney	100%	1233.20	89 / 89	98%	34.56	880 / 901
adrenal gland	100%	842.94	258 / 258	97%	33.32	222 / 230
ovary	98%	629.84	177 / 180	97%	24.93	418 / 430
liver	97%	706.03	219 / 226	96%	20.93	388 / 406
brain	93%	490.87	2452 / 2642	94%	27.45	665 / 705
pancreas	77%	303.31	252 / 328	99%	61.72	177 / 178
eye	0%	0	0 / 0	100%	28.08	80 / 80
lymph node	0%	0	0 / 0	100%	38.06	29 / 29
spleen	100%	970.94	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	51.23	45 / 45
ureter	0%	0	0 / 0	100%	38.73	1 / 1
blood vessel	100%	1332.61	1331 / 1335	0%	0	0 / 0
adipose	100%	1691.21	1200 / 1204	0%	0	0 / 0
heart	100%	1148.13	857 / 861	0%	0	0 / 0
muscle	98%	847.37	788 / 803	0%	0	0 / 0
peripheral blood	98%	943.26	909 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0000079	Biological process	regulation of cyclin-dependent protein serine/threonine kinase activity
GO_0008284	Biological process	positive regulation of cell population proliferation
GO_0045944	Biological process	positive regulation of transcription by RNA polymerase II
GO_0016528	Cellular component	sarcoplasm
GO_0005634	Cellular component	nucleus
GO_0140110	Molecular function	transcription regulator activity
GO_0005515	Molecular function	protein binding

IV. Literature review

[source]

Gene name	SERTAD1
Protein name	SERTA domain containing 1 variant (SERTA domain containing 1, isoform CRA_a) (cDNA FLJ90171 fis, clone MAMMA1000403, highly similar to SERTA domain-containing protein 1) SERTA domain-containing protein 1 (CDK4-binding protein p34SEI1) (SEI-1) (p34(SEI-1)) (Transcriptional regulator interacting with the PHD-bromodomain 1) (TRIP-Br1)
Synonyms	hCG_1777718 TRIPBR1 SEI1
Description	FUNCTION: Acts at E2F-responsive promoters as coregulator to integrate signals provided by PHD- and/or bromodomain-containing transcription factors. Stimulates E2F1/TFDP1 transcriptional activity. Renders the activity of cyclin D1/CDK4 resistant to the inhibitory effects of CDKN2A/p16INK4A.
Accessions	Q53GC0 Q9UHV2 ENST00000357949.5

SERTAD1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review