SEPTIN1 report

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I. Expression across cell types

Cell ontologyData table

Name	Number of supported studies	Average coverage
CD8-positive, alpha-beta T cell	30 studies	40% ± 18%	Explore
CD4-positive, alpha-beta T cell	24 studies	43% ± 14%	Explore
T cell	23 studies	37% ± 14%	Explore
natural killer cell	22 studies	30% ± 10%	Explore
regulatory T cell	21 studies	39% ± 17%	Explore
B cell	20 studies	27% ± 9%	Explore
mature NK T cell	15 studies	36% ± 17%	Explore
memory B cell	14 studies	28% ± 7%	Explore
CD16-positive, CD56-dim natural killer cell, human	11 studies	35% ± 12%	Explore
naive B cell	11 studies	27% ± 9%	Explore
CD16-negative, CD56-bright natural killer cell, human	10 studies	37% ± 14%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	10 studies	31% ± 11%	Explore
plasmacytoid dendritic cell	10 studies	33% ± 13%	Explore
gamma-delta T cell	10 studies	42% ± 17%	Explore
CD4-positive, alpha-beta memory T cell	9 studies	42% ± 17%	Explore
CD8-positive, alpha-beta memory T cell	9 studies	41% ± 13%	Explore
mucosal invariant T cell	8 studies	34% ± 13%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	8 studies	44% ± 11%	Explore
plasma cell	6 studies	30% ± 9%	Explore
T follicular helper cell	6 studies	38% ± 10%	Explore
CD4-positive helper T cell	5 studies	24% ± 11%	Explore
effector memory CD8-positive, alpha-beta T cell	5 studies	38% ± 10%	Explore
T-helper 17 cell	5 studies	39% ± 14%	Explore
exhausted T cell	4 studies	61% ± 1%	Explore
effector CD4-positive, alpha-beta T cell	4 studies	50% ± 18%	Explore
effector CD8-positive, alpha-beta T cell	4 studies	54% ± 6%	Explore
central memory CD8-positive, alpha-beta T cell	3 studies	32% ± 11%	Explore
plasmablast	3 studies	37% ± 15%	Explore
precursor B cell	3 studies	32% ± 4%	Explore
double negative thymocyte	3 studies	58% ± 11%	Explore
germinal center B cell	3 studies	35% ± 10%	Explore
effector memory CD4-positive, alpha-beta T cell	3 studies	47% ± 23%	Explore
group 3 innate lymphoid cell	3 studies	36% ± 12%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	3 studies	36% ± 3%	Explore

II. Expression across tissues

sc-RNAseq dataData table

Name	Number of supported studies	Average coverage
peripheral blood	9 studies	29% ± 4%	Explore
lymph node	3 studies	35% ± 3%	Explore

Bulk RNAseq dataData table

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
prostate	99%	341.96	243 / 245	98%	5.37	492 / 502
thymus	99%	366.83	648 / 653	91%	22.80	553 / 605
breast	100%	240.53	457 / 459	90%	5.93	1005 / 1118
lung	100%	522.69	578 / 578	89%	6.05	1028 / 1155
kidney	97%	270.71	86 / 89	89%	5.65	805 / 901
uterus	100%	310.04	170 / 170	85%	5.13	389 / 459
adrenal gland	95%	154.31	246 / 258	89%	5.95	205 / 230
ovary	99%	247.08	179 / 180	80%	3.30	345 / 430
intestine	99%	790.56	960 / 966	78%	4.61	412 / 527
stomach	99%	254.38	357 / 359	77%	4.85	221 / 286
bladder	100%	301.10	21 / 21	76%	5.34	385 / 504
skin	89%	199.42	1605 / 1809	87%	8.86	410 / 472
liver	94%	154.07	212 / 226	61%	3.19	248 / 406
brain	99%	210.48	2610 / 2642	55%	1.82	389 / 705
esophagus	98%	196.91	1422 / 1445	51%	2.21	93 / 183
pancreas	38%	36.80	123 / 328	83%	6.34	147 / 178
lymph node	0%	0	0 / 0	100%	111.44	29 / 29
peripheral blood	100%	2745.13	929 / 929	0%	0	0 / 0
spleen	100%	4054.74	241 / 241	0%	0	0 / 0
ureter	0%	0	0 / 0	100%	3.80	1 / 1
adipose	100%	274.14	1201 / 1204	0%	0	0 / 0
blood vessel	97%	199.38	1296 / 1335	0%	0	0 / 0
eye	0%	0	0 / 0	95%	5.58	76 / 80
tonsil	0%	0	0 / 0	89%	10.46	40 / 45
heart	69%	79.31	593 / 861	0%	0	0 / 0
muscle	11%	10.16	92 / 803	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0