POLR2C | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
CD4-positive, alpha-beta T cell	12 studies	22% ± 7%	Explore
CD8-positive, alpha-beta T cell	12 studies	20% ± 4%	Explore
regulatory T cell	12 studies	19% ± 3%	Explore
natural killer cell	11 studies	21% ± 4%	Explore
fibroblast	10 studies	23% ± 8%	Explore
CD16-negative, CD56-bright natural killer cell, human	9 studies	19% ± 3%	Explore
mucosal invariant T cell	9 studies	18% ± 2%	Explore
gamma-delta T cell	9 studies	23% ± 13%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	8 studies	19% ± 3%	Explore
B cell	7 studies	21% ± 6%	Explore
CD16-positive, CD56-dim natural killer cell, human	7 studies	20% ± 3%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	7 studies	20% ± 4%	Explore
endothelial cell	7 studies	27% ± 10%	Explore
connective tissue cell	6 studies	24% ± 7%	Explore
T cell	6 studies	20% ± 4%	Explore
smooth muscle cell	6 studies	21% ± 6%	Explore
epithelial cell	6 studies	38% ± 17%	Explore
ciliated cell	6 studies	23% ± 7%	Explore
memory B cell	6 studies	17% ± 3%	Explore
effector memory CD8-positive, alpha-beta T cell	5 studies	22% ± 6%	Explore
mature NK T cell	5 studies	17% ± 1%	Explore
myofibroblast cell	5 studies	21% ± 3%	Explore
pericyte	5 studies	23% ± 6%	Explore
type II pneumocyte	5 studies	31% ± 19%	Explore
T follicular helper cell	5 studies	19% ± 3%	Explore
CD8-positive, alpha-beta memory T cell	5 studies	21% ± 4%	Explore
CD4-positive, alpha-beta memory T cell	5 studies	20% ± 5%	Explore
hematopoietic precursor cell	3 studies	29% ± 11%	Explore
pancreatic A cell	3 studies	30% ± 6%	Explore
non-classical monocyte	3 studies	29% ± 6%	Explore
kidney loop of Henle epithelial cell	3 studies	18% ± 1%	Explore
retinal bipolar neuron	3 studies	33% ± 10%	Explore
precursor B cell	3 studies	29% ± 5%	Explore
pro-B cell	3 studies	29% ± 4%	Explore
amacrine cell	3 studies	32% ± 10%	Explore
retina horizontal cell	3 studies	27% ± 11%	Explore
Mueller cell	3 studies	22% ± 5%	Explore
abnormal cell	3 studies	20% ± 6%	Explore
exhausted T cell	3 studies	18% ± 2%	Explore
effector memory CD4-positive, alpha-beta T cell	3 studies	23% ± 10%	Explore
naive B cell	3 studies	18% ± 3%	Explore
plasmacytoid dendritic cell	3 studies	21% ± 2%	Explore
double negative thymocyte	3 studies	28% ± 15%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
peripheral blood	9 studies	19% ± 6%	Explore
eye	4 studies	25% ± 10%	Explore
lung	4 studies	27% ± 5%	Explore
pancreas	3 studies	28% ± 6%	Explore
kidney	3 studies	16% ± 1%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	3046.56	1445 / 1445	100%	44.91	183 / 183
intestine	100%	3264.95	966 / 966	100%	65.42	527 / 527
kidney	100%	3724.24	89 / 89	100%	69.84	901 / 901
lung	100%	3543.03	578 / 578	100%	69.97	1155 / 1155
ovary	100%	4135.66	180 / 180	100%	52.99	430 / 430
pancreas	100%	2043.06	328 / 328	100%	51.86	178 / 178
stomach	100%	2791.12	359 / 359	100%	60.20	286 / 286
brain	100%	2993.82	2638 / 2642	100%	63.44	705 / 705
breast	100%	3471.17	459 / 459	100%	56.06	1116 / 1118
bladder	100%	3540.81	21 / 21	100%	58.60	503 / 504
prostate	100%	3290.31	245 / 245	100%	54.26	501 / 502
skin	100%	3542.89	1809 / 1809	100%	56.29	470 / 472
uterus	100%	3750.08	170 / 170	100%	53.83	457 / 459
liver	100%	2220.00	226 / 226	100%	41.01	404 / 406
thymus	100%	3449.62	653 / 653	100%	66.53	602 / 605
adrenal gland	100%	3837.95	258 / 258	99%	66.48	228 / 230
adipose	100%	3292.04	1204 / 1204	0%	0	0 / 0
blood vessel	100%	4142.62	1335 / 1335	0%	0	0 / 0
lymph node	0%	0	0 / 0	100%	45.66	29 / 29
muscle	100%	4063.03	803 / 803	0%	0	0 / 0
spleen	100%	2945.20	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	45.16	45 / 45
ureter	0%	0	0 / 0	100%	27.43	1 / 1
heart	99%	2473.79	852 / 861	0%	0	0 / 0
eye	0%	0	0 / 0	99%	40.06	79 / 80
peripheral blood	96%	2538.74	896 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0006366	Biological process	transcription by RNA polymerase II
GO_0005665	Cellular component	RNA polymerase II, core complex
GO_0005654	Cellular component	nucleoplasm
GO_0005829	Cellular component	cytosol
GO_0005634	Cellular component	nucleus
GO_0003677	Molecular function	DNA binding
GO_0001055	Molecular function	RNA polymerase II activity
GO_0046983	Molecular function	protein dimerization activity
GO_0005515	Molecular function	protein binding

IV. Literature review

[source]

Gene name	POLR2C
Protein name	RNA polymerase II subunit C DNA-directed RNA polymerase II subunit RPB3 (RNA polymerase II subunit 3) (RNA polymerase II subunit B3) (DNA-directed RNA polymerase II 33 kDa polypeptide) (RPB33) (DNA-directed RNA polymerase II subunit C) (RPB31) HCG2025883, isoform CRA_b (POLR2C protein) (cDNA FLJ76636, highly similar to Homo sapiens polymerase (RNA) II (DNA directed) polypeptide C, 33kDa (POLR2C), transcript variant alpha, mRNA)
Synonyms	A-152E5.7 hCG_2025883
Description	FUNCTION: Core component of RNA polymerase II (Pol II), a DNA-dependent RNA polymerase which synthesizes mRNA precursors and many functional non-coding RNAs using the four ribonucleoside triphosphates as substrates. .
Accessions	ENST00000562599.5 ENST00000219252.10 P19387 H3BRR2 Q6FGR6

POLR2C report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review