Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| endothelial cell | 22 studies | 36% ± 16% | |
| astrocyte | 19 studies | 47% ± 20% | |
| oligodendrocyte | 14 studies | 41% ± 16% | |
| oligodendrocyte precursor cell | 13 studies | 51% ± 19% | |
| microglial cell | 13 studies | 45% ± 14% | |
| glutamatergic neuron | 12 studies | 47% ± 26% | |
| pericyte | 11 studies | 35% ± 15% | |
| macrophage | 11 studies | 43% ± 17% | |
| fibroblast | 11 studies | 41% ± 16% | |
| GABAergic neuron | 10 studies | 49% ± 22% | |
| smooth muscle cell | 10 studies | 31% ± 9% | |
| classical monocyte | 8 studies | 23% ± 8% | |
| epithelial cell | 8 studies | 30% ± 16% | |
| myeloid cell | 7 studies | 27% ± 10% | |
| adipocyte | 7 studies | 30% ± 8% | |
| neuron | 6 studies | 46% ± 20% | |
| interneuron | 6 studies | 55% ± 17% | |
| dendritic cell | 6 studies | 30% ± 5% | |
| mast cell | 6 studies | 24% ± 8% | |
| T cell | 6 studies | 25% ± 7% | |
| endothelial cell of lymphatic vessel | 6 studies | 33% ± 12% | |
| B cell | 5 studies | 27% ± 11% | |
| cardiac muscle cell | 5 studies | 39% ± 11% | |
| natural killer cell | 5 studies | 27% ± 8% | |
| monocyte | 5 studies | 44% ± 9% | |
| type I pneumocyte | 5 studies | 34% ± 7% | |
| type II pneumocyte | 5 studies | 33% ± 7% | |
| granule cell | 4 studies | 39% ± 2% | |
| CD8-positive, alpha-beta T cell | 4 studies | 21% ± 5% | |
| mesothelial cell | 4 studies | 34% ± 12% | |
| lymphocyte | 4 studies | 33% ± 15% | |
| Mueller cell | 4 studies | 40% ± 17% | |
| amacrine cell | 4 studies | 35% ± 10% | |
| retina horizontal cell | 4 studies | 38% ± 13% | |
| retinal cone cell | 4 studies | 34% ± 14% | |
| retinal rod cell | 4 studies | 38% ± 9% | |
| ciliated cell | 4 studies | 32% ± 13% | |
| club cell | 4 studies | 35% ± 10% | |
| basal cell | 4 studies | 39% ± 21% | |
| neutrophil | 3 studies | 20% ± 3% | |
| CD16-negative, CD56-bright natural killer cell, human | 3 studies | 23% ± 5% | |
| CD16-positive, CD56-dim natural killer cell, human | 3 studies | 22% ± 8% | |
| non-classical monocyte | 3 studies | 24% ± 4% | |
| differentiation-committed oligodendrocyte precursor | 3 studies | 49% ± 4% | |
| GABAergic interneuron | 3 studies | 40% ± 5% | |
| progenitor cell | 3 studies | 44% ± 3% | |
| plasma cell | 3 studies | 32% ± 5% | |
| CD4-positive, alpha-beta T cell | 3 studies | 22% ± 3% | |
| GABAergic amacrine cell | 3 studies | 33% ± 12% | |
| glycinergic amacrine cell | 3 studies | 31% ± 6% | |
| endothelial cell of vascular tree | 3 studies | 33% ± 20% | |
| retinal pigment epithelial cell | 3 studies | 39% ± 24% | |
| abnormal cell | 3 studies | 27% ± 14% | |
| ependymal cell | 3 studies | 54% ± 17% | |
| alveolar macrophage | 3 studies | 36% ± 8% | |
| capillary endothelial cell | 3 studies | 25% ± 6% | |
| respiratory goblet cell | 3 studies | 31% ± 13% | |
| mural cell | 3 studies | 40% ± 6% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| prostate | 100% | 2908.07 | 245 / 245 | 100% | 13.72 | 502 / 502 |
| brain | 100% | 2143.83 | 2639 / 2642 | 100% | 24.58 | 705 / 705 |
| breast | 100% | 2530.70 | 459 / 459 | 100% | 14.60 | 1115 / 1118 |
| thymus | 100% | 2726.29 | 653 / 653 | 100% | 15.75 | 603 / 605 |
| adrenal gland | 100% | 3279.30 | 258 / 258 | 100% | 11.57 | 229 / 230 |
| esophagus | 100% | 2676.76 | 1445 / 1445 | 99% | 11.83 | 182 / 183 |
| uterus | 100% | 3124.62 | 170 / 170 | 99% | 11.75 | 456 / 459 |
| ovary | 100% | 3606.14 | 180 / 180 | 99% | 12.51 | 426 / 430 |
| lung | 100% | 3435.40 | 578 / 578 | 99% | 12.18 | 1143 / 1155 |
| skin | 100% | 2606.16 | 1808 / 1809 | 98% | 12.58 | 462 / 472 |
| kidney | 100% | 1594.02 | 89 / 89 | 98% | 11.03 | 879 / 901 |
| bladder | 100% | 3012.38 | 21 / 21 | 97% | 8.63 | 490 / 504 |
| intestine | 100% | 2986.15 | 966 / 966 | 97% | 7.31 | 511 / 527 |
| stomach | 100% | 1837.36 | 359 / 359 | 97% | 8.07 | 277 / 286 |
| pancreas | 98% | 1048.94 | 323 / 328 | 98% | 11.17 | 174 / 178 |
| liver | 88% | 911.87 | 200 / 226 | 65% | 4.76 | 265 / 406 |
| adipose | 100% | 2702.60 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 15.83 | 29 / 29 |
| spleen | 100% | 3810.33 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 12.65 | 45 / 45 |
| blood vessel | 100% | 3106.77 | 1334 / 1335 | 0% | 0 | 0 / 0 |
| peripheral blood | 100% | 8378.39 | 928 / 929 | 0% | 0 | 0 / 0 |
| muscle | 99% | 1588.95 | 798 / 803 | 0% | 0 | 0 / 0 |
| heart | 98% | 2017.50 | 843 / 861 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 98% | 10.06 | 78 / 80 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0006325 | Biological process | chromatin organization |
| GO_0000122 | Biological process | negative regulation of transcription by RNA polymerase II |
| GO_0000118 | Cellular component | histone deacetylase complex |
| GO_0005654 | Cellular component | nucleoplasm |
| GO_1990391 | Cellular component | DNA repair complex |
| GO_0003677 | Molecular function | DNA binding |
| GO_0005515 | Molecular function | protein binding |
| GO_0046872 | Molecular function | metal ion binding |
| GO_0003682 | Molecular function | chromatin binding |
| Gene name | PHF21A |
| Protein name | PHD finger protein 21A (BHC80a) (BRAF35-HDAC complex protein BHC80) PHD finger protein 21A |
| Synonyms | BM-006 BHC80 KIAA1696 |
| Description | FUNCTION: Component of the BHC complex, a corepressor complex that represses transcription of neuron-specific genes in non-neuronal cells. The BHC complex is recruited at RE1/NRSE sites by REST and acts by deacetylating and demethylating specific sites on histones, thereby acting as a chromatin modifier. In the BHC complex, it may act as a scaffold. Inhibits KDM1A-mediated demethylation of 'Lys-4' of histone H3 in vitro, suggesting a role in demethylation regulation. . |
| Accessions | ENST00000524497.5 ENST00000532010.5 ENST00000531959.5 ENST00000533757.5 H0YCI1 Q96BD5 ENST00000693049.1 ENST00000690620.1 [Q96BD5-2] E9PLU5 H0YEK2 E9PR02 A0A1B0GX09 ENST00000418153.6 [Q96BD5-1] E9PNN4 ENST00000530587.6 E9PNW9 ENST00000323180.10 [Q96BD5-2] A0A1D5RMU1 E9PLV4 ENST00000529734.5 ENST00000676320.1 [Q96BD5-3] ENST00000532028.1 H0YCM5 ENST00000525438.5 ENST00000529782.5 ENST00000527782.5 ENST00000532883.5 E9PQM3 ENST00000525676.6 E9PS51 |