PDS5A report

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I. Expression across cell types

Cell ontologyData table

Name	Number of supported studies	Average coverage
endothelial cell	24 studies	37% ± 14%	Explore
astrocyte	15 studies	35% ± 16%	Explore
oligodendrocyte	13 studies	37% ± 14%	Explore
macrophage	13 studies	38% ± 16%	Explore
B cell	12 studies	27% ± 9%	Explore
glutamatergic neuron	12 studies	46% ± 26%	Explore
microglial cell	12 studies	45% ± 12%	Explore
fibroblast	12 studies	35% ± 13%	Explore
oligodendrocyte precursor cell	11 studies	38% ± 16%	Explore
GABAergic neuron	10 studies	44% ± 23%	Explore
pericyte	10 studies	32% ± 13%	Explore
smooth muscle cell	10 studies	28% ± 9%	Explore
type I pneumocyte	9 studies	36% ± 14%	Explore
myeloid cell	9 studies	33% ± 9%	Explore
epithelial cell	9 studies	40% ± 18%	Explore
adipocyte	9 studies	42% ± 11%	Explore
mast cell	9 studies	26% ± 10%	Explore
T cell	9 studies	28% ± 9%	Explore
CD4-positive, alpha-beta T cell	8 studies	23% ± 6%	Explore
CD8-positive, alpha-beta T cell	8 studies	20% ± 4%	Explore
basal cell	7 studies	34% ± 20%	Explore
dendritic cell	7 studies	38% ± 9%	Explore
endothelial cell of lymphatic vessel	7 studies	38% ± 13%	Explore
neuron	6 studies	44% ± 18%	Explore
interneuron	6 studies	52% ± 24%	Explore
club cell	6 studies	36% ± 13%	Explore
ciliated cell	6 studies	28% ± 10%	Explore
type II pneumocyte	6 studies	40% ± 9%	Explore
natural killer cell	6 studies	25% ± 6%	Explore
CD16-negative, CD56-bright natural killer cell, human	5 studies	21% ± 4%	Explore
effector memory CD8-positive, alpha-beta T cell	5 studies	23% ± 5%	Explore
retinal cone cell	5 studies	19% ± 3%	Explore
respiratory goblet cell	5 studies	32% ± 14%	Explore
monocyte	5 studies	37% ± 8%	Explore
goblet cell	5 studies	31% ± 24%	Explore
CD16-positive, CD56-dim natural killer cell, human	4 studies	21% ± 6%	Explore
granule cell	4 studies	32% ± 5%	Explore
cardiac muscle cell	4 studies	28% ± 2%	Explore
mucosal invariant T cell	4 studies	22% ± 6%	Explore
lymphocyte	4 studies	40% ± 14%	Explore
amacrine cell	4 studies	30% ± 9%	Explore
retina horizontal cell	4 studies	32% ± 7%	Explore
retinal rod cell	4 studies	25% ± 5%	Explore
naive B cell	4 studies	20% ± 3%	Explore
abnormal cell	4 studies	31% ± 18%	Explore
leukocyte	4 studies	42% ± 11%	Explore
CD8-positive, alpha-beta memory T cell	4 studies	20% ± 2%	Explore
regulatory T cell	4 studies	21% ± 5%	Explore
plasmacytoid dendritic cell	4 studies	24% ± 5%	Explore
classical monocyte	3 studies	25% ± 6%	Explore
hematopoietic precursor cell	3 studies	36% ± 12%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	3 studies	27% ± 6%	Explore
non-classical monocyte	3 studies	25% ± 5%	Explore
GABAergic interneuron	3 studies	36% ± 5%	Explore
glial cell	3 studies	26% ± 7%	Explore
progenitor cell	3 studies	33% ± 4%	Explore
plasma cell	3 studies	32% ± 6%	Explore
squamous epithelial cell	3 studies	36% ± 23%	Explore
pro-B cell	3 studies	26% ± 5%	Explore
mesothelial cell	3 studies	34% ± 7%	Explore
mononuclear phagocyte	3 studies	30% ± 9%	Explore
vein endothelial cell	3 studies	40% ± 23%	Explore
GABAergic amacrine cell	3 studies	28% ± 7%	Explore
Mueller cell	3 studies	29% ± 4%	Explore
glycinergic amacrine cell	3 studies	26% ± 1%	Explore
retinal ganglion cell	3 studies	28% ± 9%	Explore
memory B cell	3 studies	17% ± 2%	Explore
endothelial cell of vascular tree	3 studies	36% ± 20%	Explore
hepatocyte	3 studies	61% ± 18%	Explore
ependymal cell	3 studies	44% ± 12%	Explore
enteroendocrine cell	3 studies	21% ± 3%	Explore
alveolar macrophage	3 studies	43% ± 10%	Explore
muscle cell	3 studies	31% ± 21%	Explore
transit amplifying cell	3 studies	46% ± 31%	Explore
mural cell	3 studies	37% ± 12%	Explore
mucus secreting cell	3 studies	30% ± 10%	Explore

II. Expression across tissues

sc-RNAseq dataData table

Name	Number of supported studies	Average coverage
brain	17 studies	41% ± 21%	Explore
lung	7 studies	30% ± 10%	Explore
eye	5 studies	35% ± 17%	Explore
heart	4 studies	28% ± 5%	Explore
liver	4 studies	37% ± 17%	Explore
peripheral blood	3 studies	29% ± 5%	Explore
bone marrow	3 studies	23% ± 10%	Explore
intestine	3 studies	19% ± 2%	Explore
adipose	3 studies	41% ± 12%	Explore

Bulk RNAseq dataData table

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	5452.54	1445 / 1445	100%	49.26	183 / 183
lung	100%	5926.60	578 / 578	100%	39.72	1155 / 1155
ovary	100%	6242.39	180 / 180	100%	24.39	430 / 430
prostate	100%	4742.65	245 / 245	100%	33.09	502 / 502
breast	100%	5471.47	459 / 459	100%	48.50	1116 / 1118
brain	100%	3543.23	2635 / 2642	100%	25.81	705 / 705
thymus	100%	5742.14	653 / 653	100%	37.00	602 / 605
pancreas	100%	3433.99	328 / 328	99%	27.15	177 / 178
bladder	100%	5158.43	21 / 21	99%	31.40	501 / 504
kidney	100%	3636.09	89 / 89	99%	28.58	894 / 901
uterus	100%	5664.36	170 / 170	99%	32.04	455 / 459
stomach	100%	3876.19	359 / 359	99%	35.59	283 / 286
intestine	100%	5231.16	966 / 966	99%	33.13	521 / 527
adrenal gland	100%	4526.55	258 / 258	99%	20.19	227 / 230
liver	100%	3547.19	226 / 226	96%	18.55	391 / 406
skin	100%	6844.29	1809 / 1809	95%	30.83	448 / 472
adipose	100%	5626.59	1204 / 1204	0%	0	0 / 0
blood vessel	100%	4778.12	1335 / 1335	0%	0	0 / 0
lymph node	0%	0	0 / 0	100%	34.94	29 / 29
muscle	100%	3521.80	803 / 803	0%	0	0 / 0
spleen	100%	4814.08	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	34.73	45 / 45
ureter	0%	0	0 / 0	100%	12.17	1 / 1
heart	98%	2754.01	845 / 861	0%	0	0 / 0
eye	0%	0	0 / 0	86%	16.21	69 / 80
peripheral blood	84%	3437.96	780 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0