NUFIP2 report

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I. Expression across cell types

Cell ontologyData table

Name	Number of supported studies	Average coverage
endothelial cell	28 studies	31% ± 12%	Explore
macrophage	25 studies	30% ± 13%	Explore
fibroblast	22 studies	26% ± 12%	Explore
classical monocyte	15 studies	24% ± 12%	Explore
natural killer cell	13 studies	23% ± 8%	Explore
astrocyte	13 studies	30% ± 17%	Explore
B cell	12 studies	22% ± 6%	Explore
monocyte	11 studies	30% ± 11%	Explore
ciliated cell	11 studies	26% ± 13%	Explore
non-classical monocyte	11 studies	27% ± 14%	Explore
conventional dendritic cell	11 studies	26% ± 14%	Explore
microglial cell	11 studies	32% ± 16%	Explore
plasmacytoid dendritic cell	10 studies	22% ± 8%	Explore
epithelial cell	10 studies	37% ± 20%	Explore
oligodendrocyte	10 studies	33% ± 14%	Explore
pericyte	9 studies	27% ± 8%	Explore
smooth muscle cell	9 studies	23% ± 9%	Explore
CD8-positive, alpha-beta T cell	9 studies	21% ± 5%	Explore
myeloid cell	9 studies	29% ± 10%	Explore
basal cell	9 studies	31% ± 11%	Explore
dendritic cell	8 studies	33% ± 17%	Explore
mast cell	8 studies	21% ± 8%	Explore
T cell	7 studies	31% ± 16%	Explore
endothelial cell of lymphatic vessel	7 studies	29% ± 9%	Explore
type I pneumocyte	7 studies	25% ± 7%	Explore
CD4-positive, alpha-beta T cell	7 studies	20% ± 4%	Explore
glutamatergic neuron	7 studies	40% ± 25%	Explore
regulatory T cell	7 studies	19% ± 4%	Explore
secretory cell	6 studies	24% ± 11%	Explore
leukocyte	6 studies	28% ± 4%	Explore
naive B cell	6 studies	23% ± 4%	Explore
CD16-negative, CD56-bright natural killer cell, human	6 studies	21% ± 5%	Explore
capillary endothelial cell	6 studies	21% ± 9%	Explore
adipocyte	6 studies	28% ± 9%	Explore
CD8-positive, alpha-beta memory T cell	6 studies	26% ± 7%	Explore
endothelial cell of vascular tree	6 studies	27% ± 9%	Explore
GABAergic neuron	6 studies	37% ± 22%	Explore
oligodendrocyte precursor cell	6 studies	34% ± 18%	Explore
alveolar macrophage	5 studies	26% ± 12%	Explore
type II pneumocyte	5 studies	25% ± 6%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	5 studies	23% ± 4%	Explore
mononuclear phagocyte	5 studies	24% ± 9%	Explore
CD16-positive, CD56-dim natural killer cell, human	5 studies	27% ± 6%	Explore
mature NK T cell	5 studies	23% ± 4%	Explore
neuron	5 studies	28% ± 16%	Explore
mucosal invariant T cell	5 studies	19% ± 3%	Explore
club cell	5 studies	23% ± 5%	Explore
lymphocyte	5 studies	31% ± 9%	Explore
goblet cell	5 studies	29% ± 17%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	4 studies	25% ± 9%	Explore
effector memory CD8-positive, alpha-beta T cell	4 studies	24% ± 3%	Explore
hematopoietic precursor cell	4 studies	31% ± 11%	Explore
abnormal cell	4 studies	26% ± 13%	Explore
retinal cone cell	4 studies	27% ± 7%	Explore
cardiac muscle cell	4 studies	19% ± 3%	Explore
Mueller cell	4 studies	21% ± 3%	Explore
gamma-delta T cell	4 studies	31% ± 10%	Explore
memory B cell	4 studies	26% ± 7%	Explore
connective tissue cell	4 studies	26% ± 8%	Explore
interneuron	4 studies	42% ± 26%	Explore
glomerular endothelial cell	3 studies	17% ± 0%	Explore
GABAergic interneuron	3 studies	17% ± 1%	Explore
progenitor cell	3 studies	18% ± 2%	Explore
retinal ganglion cell	3 studies	24% ± 6%	Explore
retina horizontal cell	3 studies	23% ± 7%	Explore
retinal pigment epithelial cell	3 studies	36% ± 6%	Explore
vein endothelial cell	3 studies	36% ± 12%	Explore
rod bipolar cell	3 studies	24% ± 6%	Explore
CD4-positive, alpha-beta memory T cell	3 studies	28% ± 5%	Explore
ependymal cell	3 studies	36% ± 20%	Explore
neutrophil	3 studies	17% ± 1%	Explore
enteroendocrine cell	3 studies	19% ± 3%	Explore
intestinal crypt stem cell	3 studies	18% ± 1%	Explore
myofibroblast cell	3 studies	28% ± 7%	Explore
transit amplifying cell	3 studies	31% ± 17%	Explore

II. Expression across tissues

sc-RNAseq dataData table

Name	Number of supported studies	Average coverage
brain	13 studies	32% ± 19%	Explore
lung	8 studies	26% ± 10%	Explore
eye	6 studies	26% ± 9%	Explore
peripheral blood	5 studies	30% ± 9%	Explore
adipose	4 studies	22% ± 5%	Explore
uterus	3 studies	35% ± 11%	Explore
liver	3 studies	33% ± 13%	Explore
intestine	3 studies	23% ± 4%	Explore

Bulk RNAseq dataData table

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	6460.07	1445 / 1445	100%	51.16	183 / 183
lung	100%	11113.69	578 / 578	100%	40.01	1155 / 1155
breast	100%	6570.24	459 / 459	100%	54.74	1117 / 1118
uterus	100%	6104.59	170 / 170	100%	35.42	458 / 459
bladder	100%	6266.10	21 / 21	100%	37.34	502 / 504
prostate	100%	6472.25	245 / 245	100%	29.48	500 / 502
thymus	100%	6944.27	652 / 653	100%	29.56	602 / 605
ovary	100%	6024.74	180 / 180	99%	20.37	427 / 430
pancreas	100%	3707.11	327 / 328	99%	35.78	177 / 178
brain	99%	3981.95	2611 / 2642	100%	32.81	705 / 705
intestine	100%	6414.30	966 / 966	99%	32.86	520 / 527
stomach	100%	5408.96	359 / 359	99%	37.45	282 / 286
kidney	100%	4610.72	89 / 89	99%	30.15	888 / 901
skin	100%	7572.17	1809 / 1809	98%	37.22	462 / 472
liver	100%	4477.83	226 / 226	98%	19.19	397 / 406
adrenal gland	100%	6339.97	258 / 258	97%	22.57	224 / 230
adipose	100%	7459.10	1204 / 1204	0%	0	0 / 0
lymph node	0%	0	0 / 0	100%	26.40	29 / 29
muscle	100%	4701.04	803 / 803	0%	0	0 / 0
spleen	100%	8304.10	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	35.95	45 / 45
ureter	0%	0	0 / 0	100%	14.51	1 / 1
blood vessel	100%	6107.39	1334 / 1335	0%	0	0 / 0
heart	98%	4615.11	847 / 861	0%	0	0 / 0
peripheral blood	96%	6221.54	894 / 929	0%	0	0 / 0
eye	0%	0	0 / 0	91%	20.68	73 / 80
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0