MIDN | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
endothelial cell	36 studies	37% ± 17%	Explore
classical monocyte	24 studies	39% ± 16%	Explore
natural killer cell	20 studies	24% ± 8%	Explore
macrophage	19 studies	27% ± 10%	Explore
non-classical monocyte	19 studies	40% ± 18%	Explore
pericyte	18 studies	39% ± 21%	Explore
fibroblast	17 studies	31% ± 17%	Explore
conventional dendritic cell	16 studies	31% ± 13%	Explore
monocyte	15 studies	30% ± 12%	Explore
ciliated cell	15 studies	37% ± 19%	Explore
capillary endothelial cell	14 studies	25% ± 9%	Explore
basal cell	14 studies	29% ± 14%	Explore
B cell	13 studies	23% ± 6%	Explore
smooth muscle cell	13 studies	33% ± 12%	Explore
epithelial cell	13 studies	38% ± 21%	Explore
secretory cell	11 studies	31% ± 13%	Explore
endothelial cell of artery	11 studies	34% ± 9%	Explore
endothelial cell of vascular tree	11 studies	37% ± 17%	Explore
CD16-positive, CD56-dim natural killer cell, human	10 studies	29% ± 11%	Explore
vein endothelial cell	10 studies	28% ± 8%	Explore
memory B cell	10 studies	21% ± 4%	Explore
dendritic cell	9 studies	33% ± 18%	Explore
endothelial cell of lymphatic vessel	9 studies	28% ± 10%	Explore
neutrophil	9 studies	25% ± 6%	Explore
mast cell	8 studies	25% ± 6%	Explore
goblet cell	8 studies	30% ± 9%	Explore
plasmacytoid dendritic cell	8 studies	21% ± 7%	Explore
T cell	7 studies	27% ± 9%	Explore
abnormal cell	7 studies	24% ± 8%	Explore
myeloid cell	7 studies	32% ± 13%	Explore
type I pneumocyte	6 studies	30% ± 8%	Explore
type II pneumocyte	6 studies	24% ± 9%	Explore
respiratory goblet cell	6 studies	24% ± 8%	Explore
naive B cell	6 studies	18% ± 2%	Explore
mononuclear phagocyte	6 studies	24% ± 7%	Explore
CD16-negative, CD56-bright natural killer cell, human	6 studies	27% ± 9%	Explore
CD8-positive, alpha-beta T cell	6 studies	23% ± 9%	Explore
mature NK T cell	6 studies	25% ± 8%	Explore
enterocyte	6 studies	27% ± 6%	Explore
gamma-delta T cell	6 studies	31% ± 10%	Explore
astrocyte	6 studies	22% ± 6%	Explore
CD8-positive, alpha-beta memory T cell	6 studies	25% ± 7%	Explore
oligodendrocyte precursor cell	6 studies	26% ± 7%	Explore
connective tissue cell	6 studies	24% ± 8%	Explore
club cell	4 studies	35% ± 14%	Explore
squamous epithelial cell	4 studies	48% ± 21%	Explore
leukocyte	4 studies	29% ± 4%	Explore
myofibroblast cell	4 studies	37% ± 19%	Explore
mucosal invariant T cell	4 studies	19% ± 3%	Explore
retinal pigment epithelial cell	4 studies	30% ± 10%	Explore
luminal hormone-sensing cell of mammary gland	4 studies	41% ± 12%	Explore
duct epithelial cell	3 studies	16% ± 0%	Explore
pancreatic A cell	3 studies	25% ± 6%	Explore
effector CD8-positive, alpha-beta T cell	3 studies	19% ± 2%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	3 studies	16% ± 1%	Explore
CD4-positive, alpha-beta T cell	3 studies	16% ± 1%	Explore
effector memory CD8-positive, alpha-beta T cell	3 studies	36% ± 8%	Explore
precursor B cell	3 studies	23% ± 3%	Explore
brush cell	3 studies	25% ± 9%	Explore
tissue-resident macrophage	3 studies	33% ± 19%	Explore
Mueller cell	3 studies	21% ± 3%	Explore
intermediate monocyte	3 studies	53% ± 21%	Explore
innate lymphoid cell	3 studies	25% ± 5%	Explore
regulatory T cell	3 studies	18% ± 2%	Explore
endothelial cell of sinusoid	3 studies	20% ± 3%	Explore
luminal cell of prostate epithelium	3 studies	39% ± 7%	Explore
muscle cell	3 studies	21% ± 5%	Explore
enteroendocrine cell	3 studies	29% ± 6%	Explore
keratinocyte	3 studies	24% ± 7%	Explore
neuron	3 studies	31% ± 15%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
lung	15 studies	26% ± 12%	Explore
peripheral blood	9 studies	29% ± 12%	Explore
intestine	7 studies	26% ± 9%	Explore
uterus	4 studies	41% ± 15%	Explore
breast	4 studies	30% ± 10%	Explore
brain	4 studies	18% ± 2%	Explore
liver	4 studies	19% ± 2%	Explore
pancreas	3 studies	23% ± 5%	Explore
kidney	3 studies	23% ± 9%	Explore
bone marrow	3 studies	19% ± 1%	Explore
eye	3 studies	30% ± 13%	Explore
esophagus	3 studies	29% ± 12%	Explore
prostate	3 studies	19% ± 3%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
intestine	100%	8582.67	965 / 966	100%	101.29	527 / 527
esophagus	100%	9469.03	1443 / 1445	100%	124.99	183 / 183
prostate	100%	7068.22	245 / 245	100%	87.57	501 / 502
uterus	100%	5354.55	170 / 170	100%	106.47	458 / 459
lung	100%	11480.67	578 / 578	99%	93.66	1148 / 1155
bladder	100%	7366.00	21 / 21	99%	91.60	500 / 504
breast	100%	7442.70	458 / 459	99%	103.34	1109 / 1118
skin	100%	9966.71	1808 / 1809	99%	80.05	466 / 472
thymus	100%	6443.12	650 / 653	99%	85.09	599 / 605
ovary	98%	9849.97	177 / 180	100%	100.99	430 / 430
adrenal gland	100%	9784.78	258 / 258	98%	98.74	226 / 230
kidney	100%	7007.11	89 / 89	98%	96.39	885 / 901
stomach	95%	7266.13	342 / 359	100%	101.80	286 / 286
brain	89%	3116.24	2341 / 2642	100%	134.57	704 / 705
pancreas	86%	3560.36	283 / 328	99%	108.67	177 / 178
liver	96%	4599.27	217 / 226	86%	43.51	349 / 406
lymph node	0%	0	0 / 0	100%	66.38	29 / 29
spleen	100%	8818.73	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	88.96	45 / 45
ureter	0%	0	0 / 0	100%	66.14	1 / 1
muscle	100%	12832.79	799 / 803	0%	0	0 / 0
adipose	100%	8809.91	1198 / 1204	0%	0	0 / 0
blood vessel	99%	6929.85	1326 / 1335	0%	0	0 / 0
eye	0%	0	0 / 0	99%	53.39	79 / 80
heart	99%	7652.43	849 / 861	0%	0	0 / 0
peripheral blood	98%	10654.28	915 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0010499	Biological process	proteasomal ubiquitin-independent protein catabolic process
GO_0033132	Biological process	negative regulation of glucokinase activity
GO_0046676	Biological process	negative regulation of insulin secretion
GO_0008150	Biological process	biological_process
GO_0005730	Cellular component	nucleolus
GO_0005737	Cellular component	cytoplasm
GO_0005829	Cellular component	cytosol
GO_0005634	Cellular component	nucleus
GO_0019900	Molecular function	kinase binding
GO_0005515	Molecular function	protein binding
GO_0060090	Molecular function	molecular adaptor activity
GO_0003674	Molecular function	molecular_function

IV. Literature review

[source]

Gene name	MIDN
Protein name	Midnolin (Midbrain nucleolar protein) Midnolin
Synonyms	hCG_21588
Description	FUNCTION: Facilitates the ubiquitin-independent proteasomal degradation of stimulus-induced transcription factors such as FOSB, EGR1, NR4A1, and IRF4 to the proteasome for degradation . Promotes also the degradation of other substrates such as CBX4 (By similarity). Plays a role in inhibiting the activity of glucokinase GCK and both glucose-induced and basal insulin secretion. .
Accessions	ENST00000300952.7 ENST00000591446.7 Q504T8 ENST00000682408.1 A0A804HKJ8

MIDN report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review