LINC-PINT report

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I. Expression across cell types

Cell ontologyData table

Name	Number of supported studies	Average coverage
B cell	14 studies	30% ± 13%	Explore
natural killer cell	11 studies	30% ± 13%	Explore
endothelial cell	11 studies	43% ± 24%	Explore
T cell	10 studies	41% ± 21%	Explore
plasmacytoid dendritic cell	10 studies	39% ± 19%	Explore
naive B cell	9 studies	26% ± 10%	Explore
regulatory T cell	9 studies	34% ± 14%	Explore
CD8-positive, alpha-beta T cell	8 studies	27% ± 10%	Explore
mature NK T cell	7 studies	30% ± 13%	Explore
astrocyte	7 studies	51% ± 25%	Explore
CD4-positive, alpha-beta T cell	7 studies	33% ± 10%	Explore
plasma cell	6 studies	24% ± 11%	Explore
glutamatergic neuron	6 studies	57% ± 32%	Explore
oligodendrocyte	6 studies	48% ± 21%	Explore
conventional dendritic cell	6 studies	21% ± 3%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	5 studies	27% ± 10%	Explore
smooth muscle cell	5 studies	42% ± 24%	Explore
mucosal invariant T cell	5 studies	34% ± 12%	Explore
pericyte	5 studies	26% ± 17%	Explore
memory B cell	5 studies	31% ± 11%	Explore
dendritic cell	4 studies	26% ± 15%	Explore
effector CD8-positive, alpha-beta T cell	4 studies	33% ± 13%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	4 studies	31% ± 13%	Explore
microglial cell	4 studies	51% ± 23%	Explore
fibroblast	4 studies	41% ± 24%	Explore
CD8-positive, alpha-beta memory T cell	4 studies	45% ± 15%	Explore
gamma-delta T cell	4 studies	43% ± 16%	Explore
mast cell	4 studies	28% ± 8%	Explore
endothelial cell of lymphatic vessel	4 studies	44% ± 25%	Explore
CD4-positive, alpha-beta memory T cell	3 studies	53% ± 6%	Explore
classical monocyte	3 studies	24% ± 11%	Explore
effector CD4-positive, alpha-beta T cell	3 studies	46% ± 13%	Explore
leukocyte	3 studies	52% ± 9%	Explore
GABAergic neuron	3 studies	74% ± 28%	Explore
oligodendrocyte precursor cell	3 studies	50% ± 24%	Explore
interneuron	3 studies	44% ± 27%	Explore
myeloid cell	3 studies	37% ± 15%	Explore
abnormal cell	3 studies	20% ± 3%	Explore
CD16-negative, CD56-bright natural killer cell, human	3 studies	35% ± 11%	Explore
T follicular helper cell	3 studies	37% ± 14%	Explore
macrophage	3 studies	45% ± 13%	Explore

II. Expression across tissues

sc-RNAseq dataData table

Name	Number of supported studies	Average coverage
brain	8 studies	44% ± 30%	Explore
lung	3 studies	30% ± 15%	Explore
peripheral blood	3 studies	32% ± 11%	Explore

Bulk RNAseq dataData table

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
brain	99%	1251.48	2617 / 2642	98%	3.07	693 / 705
thymus	100%	3094.26	653 / 653	93%	2.66	562 / 605
prostate	100%	2244.37	244 / 245	87%	2.23	438 / 502
adrenal gland	100%	1262.03	258 / 258	83%	2.07	190 / 230
ovary	100%	3280.61	180 / 180	77%	1.81	333 / 430
lung	100%	2723.22	578 / 578	70%	2.60	807 / 1155
kidney	99%	1410.21	88 / 89	65%	2.00	585 / 901
intestine	92%	1199.66	890 / 966	65%	1.64	342 / 527
bladder	100%	1587.86	21 / 21	52%	1.66	264 / 504
skin	87%	665.27	1580 / 1809	64%	1.31	300 / 472
stomach	84%	759.26	303 / 359	64%	1.88	184 / 286
esophagus	83%	916.47	1205 / 1445	65%	1.36	119 / 183
breast	100%	1895.87	458 / 459	45%	1.10	504 / 1118
uterus	99%	2501.72	169 / 170	34%	1.06	158 / 459
pancreas	50%	301.75	163 / 328	83%	1.87	147 / 178
spleen	100%	1758.02	241 / 241	0%	0	0 / 0
adipose	100%	1900.10	1200 / 1204	0%	0	0 / 0
blood vessel	100%	1959.83	1330 / 1335	0%	0	0 / 0
muscle	99%	2110.79	796 / 803	0%	0	0 / 0
liver	69%	521.52	155 / 226	31%	0.48	124 / 406
heart	96%	1821.55	823 / 861	0%	0	0 / 0
peripheral blood	93%	1451.35	860 / 929	0%	0	0 / 0
lymph node	0%	0	0 / 0	86%	2.57	25 / 29
eye	0%	0	0 / 0	23%	0.36	18 / 80
tonsil	0%	0	0 / 0	13%	0.18	6 / 45
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1