LAGE3 report

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I. Expression across cell types

Cell ontologyData table

Name	Number of supported studies	Average coverage
CD8-positive, alpha-beta T cell	11 studies	24% ± 6%	Explore
CD4-positive, alpha-beta T cell	10 studies	25% ± 7%	Explore
macrophage	9 studies	23% ± 9%	Explore
plasmacytoid dendritic cell	8 studies	28% ± 9%	Explore
T cell	7 studies	19% ± 3%	Explore
conventional dendritic cell	7 studies	27% ± 12%	Explore
endothelial cell	6 studies	29% ± 10%	Explore
epithelial cell	6 studies	32% ± 16%	Explore
natural killer cell	6 studies	27% ± 7%	Explore
plasma cell	5 studies	26% ± 12%	Explore
CD16-negative, CD56-bright natural killer cell, human	5 studies	17% ± 1%	Explore
fibroblast	5 studies	25% ± 9%	Explore
ciliated cell	5 studies	27% ± 10%	Explore
regulatory T cell	5 studies	22% ± 4%	Explore
mast cell	5 studies	19% ± 4%	Explore
hematopoietic precursor cell	4 studies	37% ± 17%	Explore
plasmablast	4 studies	43% ± 18%	Explore
CD4-positive, alpha-beta memory T cell	4 studies	22% ± 2%	Explore
CD8-positive, alpha-beta memory T cell	4 studies	21% ± 5%	Explore
basal cell	4 studies	30% ± 13%	Explore
pancreatic A cell	4 studies	28% ± 7%	Explore
erythroblast	4 studies	35% ± 18%	Explore
myeloid cell	4 studies	21% ± 8%	Explore
endothelial cell of lymphatic vessel	4 studies	21% ± 7%	Explore
T follicular helper cell	4 studies	16% ± 1%	Explore
abnormal cell	4 studies	33% ± 11%	Explore
type B pancreatic cell	3 studies	33% ± 5%	Explore
classical monocyte	3 studies	21% ± 6%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	3 studies	19% ± 2%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	3 studies	23% ± 5%	Explore
non-classical monocyte	3 studies	27% ± 3%	Explore
B cell	3 studies	23% ± 6%	Explore
gamma-delta T cell	3 studies	38% ± 22%	Explore
common myeloid progenitor	3 studies	33% ± 14%	Explore
hematopoietic stem cell	3 studies	20% ± 5%	Explore
monocyte	3 studies	20% ± 6%	Explore
exhausted T cell	3 studies	21% ± 4%	Explore
dendritic cell	3 studies	39% ± 10%	Explore
goblet cell	3 studies	20% ± 6%	Explore
erythrocyte	3 studies	39% ± 15%	Explore

II. Expression across tissues

sc-RNAseq dataData table

Name	Number of supported studies	Average coverage
peripheral blood	5 studies	18% ± 4%	Explore
lung	5 studies	27% ± 10%	Explore
pancreas	3 studies	28% ± 8%	Explore

Bulk RNAseq dataData table

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
brain	100%	1310.01	2642 / 2642	100%	80.03	705 / 705
ovary	100%	685.96	180 / 180	100%	117.42	430 / 430
skin	100%	717.05	1809 / 1809	100%	111.64	472 / 472
uterus	100%	492.33	170 / 170	100%	137.74	459 / 459
adrenal gland	100%	1074.78	258 / 258	100%	101.66	229 / 230
esophagus	100%	481.53	1444 / 1445	99%	54.72	182 / 183
stomach	100%	462.28	359 / 359	99%	78.12	284 / 286
prostate	100%	691.45	245 / 245	99%	76.35	498 / 502
pancreas	100%	540.81	327 / 328	99%	54.81	177 / 178
intestine	100%	530.12	966 / 966	99%	81.53	522 / 527
breast	100%	498.07	459 / 459	99%	111.79	1103 / 1118
thymus	99%	415.84	647 / 653	99%	73.24	600 / 605
liver	100%	437.23	225 / 226	99%	70.67	400 / 406
bladder	100%	688.52	21 / 21	98%	96.25	494 / 504
lung	98%	455.32	564 / 578	99%	76.40	1140 / 1155
kidney	100%	459.89	89 / 89	84%	27.78	760 / 901
eye	0%	0	0 / 0	100%	87.74	80 / 80
lymph node	0%	0	0 / 0	100%	166.64	29 / 29
spleen	100%	629.83	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	107.78	45 / 45
ureter	0%	0	0 / 0	100%	50.88	1 / 1
adipose	99%	448.29	1197 / 1204	0%	0	0 / 0
muscle	99%	555.48	794 / 803	0%	0	0 / 0
blood vessel	98%	364.07	1308 / 1335	0%	0	0 / 0
heart	98%	535.69	843 / 861	0%	0	0 / 0
peripheral blood	85%	379.63	794 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0