IFRD1 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
endothelial cell	28 studies	28% ± 10%	Explore
fibroblast	25 studies	28% ± 11%	Explore
B cell	21 studies	23% ± 5%	Explore
macrophage	21 studies	25% ± 6%	Explore
natural killer cell	21 studies	24% ± 9%	Explore
smooth muscle cell	16 studies	29% ± 10%	Explore
pericyte	16 studies	34% ± 14%	Explore
T cell	15 studies	25% ± 9%	Explore
CD8-positive, alpha-beta T cell	15 studies	22% ± 5%	Explore
CD4-positive, alpha-beta T cell	14 studies	24% ± 6%	Explore
CD16-negative, CD56-bright natural killer cell, human	12 studies	29% ± 15%	Explore
classical monocyte	12 studies	23% ± 8%	Explore
plasmacytoid dendritic cell	11 studies	27% ± 10%	Explore
naive B cell	11 studies	24% ± 8%	Explore
memory B cell	11 studies	26% ± 9%	Explore
regulatory T cell	11 studies	25% ± 8%	Explore
monocyte	10 studies	22% ± 6%	Explore
non-classical monocyte	10 studies	23% ± 7%	Explore
connective tissue cell	10 studies	25% ± 5%	Explore
conventional dendritic cell	10 studies	30% ± 11%	Explore
basal cell	10 studies	27% ± 9%	Explore
mature NK T cell	9 studies	21% ± 3%	Explore
epithelial cell	9 studies	42% ± 17%	Explore
gamma-delta T cell	9 studies	31% ± 13%	Explore
astrocyte	9 studies	32% ± 14%	Explore
neutrophil	8 studies	29% ± 10%	Explore
leukocyte	8 studies	25% ± 9%	Explore
myofibroblast cell	8 studies	23% ± 9%	Explore
endothelial cell of vascular tree	8 studies	24% ± 5%	Explore
adipocyte	8 studies	24% ± 7%	Explore
CD16-positive, CD56-dim natural killer cell, human	7 studies	25% ± 10%	Explore
capillary endothelial cell	7 studies	19% ± 3%	Explore
mucosal invariant T cell	7 studies	28% ± 12%	Explore
myeloid cell	7 studies	26% ± 12%	Explore
mast cell	6 studies	23% ± 5%	Explore
type I pneumocyte	6 studies	22% ± 4%	Explore
effector memory CD8-positive, alpha-beta T cell	6 studies	26% ± 7%	Explore
microglial cell	6 studies	23% ± 5%	Explore
secretory cell	6 studies	19% ± 4%	Explore
CD8-positive, alpha-beta memory T cell	6 studies	30% ± 11%	Explore
platelet	6 studies	23% ± 7%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	5 studies	20% ± 5%	Explore
mononuclear phagocyte	5 studies	23% ± 8%	Explore
abnormal cell	5 studies	28% ± 11%	Explore
precursor B cell	5 studies	23% ± 4%	Explore
enterocyte	5 studies	24% ± 7%	Explore
T follicular helper cell	5 studies	29% ± 10%	Explore
innate lymphoid cell	5 studies	30% ± 13%	Explore
dendritic cell	5 studies	29% ± 13%	Explore
goblet cell	5 studies	22% ± 4%	Explore
endothelial cell of lymphatic vessel	4 studies	26% ± 2%	Explore
type II pneumocyte	4 studies	19% ± 5%	Explore
immature B cell	4 studies	29% ± 11%	Explore
cardiac muscle cell	4 studies	22% ± 2%	Explore
luminal hormone-sensing cell of mammary gland	4 studies	21% ± 6%	Explore
GABAergic neuron	4 studies	31% ± 11%	Explore
glutamatergic neuron	4 studies	42% ± 17%	Explore
oligodendrocyte precursor cell	4 studies	22% ± 6%	Explore
oligodendrocyte	4 studies	26% ± 3%	Explore
squamous epithelial cell	3 studies	37% ± 23%	Explore
pancreatic A cell	3 studies	22% ± 9%	Explore
effector CD4-positive, alpha-beta T cell	3 studies	29% ± 12%	Explore
effector CD8-positive, alpha-beta T cell	3 studies	23% ± 6%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	3 studies	26% ± 4%	Explore
plasmablast	3 studies	34% ± 11%	Explore
glomerular endothelial cell	3 studies	40% ± 10%	Explore
kidney loop of Henle epithelial cell	3 studies	25% ± 8%	Explore
plasma cell	3 studies	28% ± 9%	Explore
retinal pigment epithelial cell	3 studies	40% ± 10%	Explore
ciliated cell	3 studies	38% ± 18%	Explore
Mueller cell	3 studies	17% ± 2%	Explore
effector memory CD4-positive, alpha-beta T cell	3 studies	28% ± 1%	Explore
vein endothelial cell	3 studies	17% ± 0%	Explore
ependymal cell	3 studies	33% ± 19%	Explore
glial cell	3 studies	22% ± 9%	Explore
group 3 innate lymphoid cell	3 studies	42% ± 17%	Explore
CD4-positive, alpha-beta memory T cell	3 studies	27% ± 10%	Explore
myoepithelial cell	3 studies	40% ± 13%	Explore
progenitor cell of mammary luminal epithelium	3 studies	35% ± 7%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
lung	9 studies	23% ± 4%	Explore
peripheral blood	8 studies	25% ± 8%	Explore
intestine	7 studies	24% ± 9%	Explore
brain	7 studies	32% ± 10%	Explore
uterus	5 studies	27% ± 10%	Explore
kidney	4 studies	23% ± 5%	Explore
breast	4 studies	29% ± 7%	Explore
liver	4 studies	20% ± 2%	Explore
eye	3 studies	33% ± 14%	Explore
lymph node	3 studies	24% ± 4%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	3614.36	1445 / 1445	100%	5.56	183 / 183
uterus	100%	3513.31	170 / 170	100%	4.82	459 / 459
thymus	100%	4322.48	653 / 653	100%	4.13	604 / 605
pancreas	100%	7830.37	328 / 328	99%	4.37	177 / 178
brain	99%	2523.60	2626 / 2642	100%	6.43	705 / 705
prostate	100%	4858.84	244 / 245	100%	5.61	501 / 502
adrenal gland	100%	3698.92	258 / 258	99%	5.27	228 / 230
bladder	100%	3286.24	21 / 21	99%	4.48	499 / 504
ovary	100%	4585.44	180 / 180	99%	3.31	424 / 430
lung	100%	6221.95	578 / 578	99%	4.22	1138 / 1155
breast	100%	5081.65	459 / 459	98%	3.90	1095 / 1118
kidney	100%	3156.91	89 / 89	97%	4.06	876 / 901
intestine	100%	3797.17	966 / 966	97%	4.16	510 / 527
stomach	100%	4183.91	359 / 359	95%	4.10	272 / 286
liver	100%	2819.37	225 / 226	91%	2.57	371 / 406
skin	100%	3164.84	1804 / 1809	91%	4.11	428 / 472
blood vessel	100%	5895.22	1335 / 1335	0%	0	0 / 0
lymph node	0%	0	0 / 0	100%	2.51	29 / 29
spleen	100%	3367.15	241 / 241	0%	0	0 / 0
ureter	0%	0	0 / 0	100%	2.41	1 / 1
adipose	100%	4970.73	1203 / 1204	0%	0	0 / 0
muscle	100%	4222.57	802 / 803	0%	0	0 / 0
peripheral blood	98%	5197.25	912 / 929	0%	0	0 / 0
heart	97%	2946.16	831 / 861	0%	0	0 / 0
tonsil	0%	0	0 / 0	89%	2.65	40 / 45
eye	0%	0	0 / 0	71%	2.61	57 / 80
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0030517	Biological process	negative regulation of axon extension
GO_0043403	Biological process	skeletal muscle tissue regeneration
GO_0014706	Biological process	striated muscle tissue development
GO_0048671	Biological process	negative regulation of collateral sprouting
GO_0007518	Biological process	myoblast fate determination
GO_0042692	Biological process	muscle cell differentiation
GO_0016528	Cellular component	sarcoplasm
GO_0005634	Cellular component	nucleus

IV. Literature review

[source]

Gene name	IFRD1
Protein name	Interferon-related developmental regulator 1 (Nerve growth factor-inducible protein PC4) Uncharacterized protein IFRD1 Interferon related developmental regulator 1 Interferon-related developmental regulator 1
Synonyms	tcag7.54 hCG_15767
Description	FUNCTION: Could play a role in regulating gene activity in the proliferative and/or differentiative pathways induced by NGF. May be an autocrine factor that attenuates or amplifies the initial ligand-induced signal (By similarity). .
Accessions	O00458 ENST00000535603.5 [O00458-2] ENST00000403825.8 [O00458-1] H0YEE3 ENST00000417662.1 ENST00000443101.6 C9JLG5 C9JNM6 E9PMY4 ENST00000429071.5 ENST00000674915.1 ENST00000005558.8 [O00458-1] Q75M98 Q75M99 ENST00000462155.2 ENST00000675578.1 [O00458-1] ENST00000621379.4 [O00458-2] C9JA65 ENST00000432734.1 A0A6Q8PF03 A4D0U1 ENST00000674887.1 C9J311 C9JK78 A0A6Q8PFA5 A0A6Q8PH75 ENST00000675041.1 ENST00000675717.1 ENST00000476927.5 ENST00000440625.5 A0A6Q8PHN0 ENST00000445335.1 Q75MS4 C9J7U6

IFRD1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review