GOLPH3 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0045053Biological processprotein retention in Golgi apparatus
GO_0060352Biological processcell adhesion molecule production
GO_0010821Biological processregulation of mitochondrion organization
GO_0006890Biological processretrograde vesicle-mediated transport, Golgi to endoplasmic reticulum
GO_0090161Biological processGolgi ribbon formation
GO_0030032Biological processlamellipodium assembly
GO_0072752Biological processcellular response to rapamycin
GO_0090164Biological processasymmetric Golgi ribbon formation
GO_0009101Biological processglycoprotein biosynthetic process
GO_0048194Biological processGolgi vesicle budding
GO_0050714Biological processpositive regulation of protein secretion
GO_0140450Biological processprotein targeting to Golgi apparatus
GO_0007030Biological processGolgi organization
GO_0043066Biological processnegative regulation of apoptotic process
GO_0050901Biological processleukocyte tethering or rolling
GO_0010467Biological processgene expression
GO_0043001Biological processGolgi to plasma membrane protein transport
GO_0032008Biological processpositive regulation of TOR signaling
GO_0016477Biological processcell migration
GO_0009306Biological processprotein secretion
GO_0005886Cellular componentplasma membrane
GO_0031985Cellular componentGolgi cisterna
GO_0005739Cellular componentmitochondrion
GO_0005758Cellular componentmitochondrial intermembrane space
GO_0005794Cellular componentGolgi apparatus
GO_0005802Cellular componenttrans-Golgi network
GO_0000139Cellular componentGolgi membrane
GO_0005829Cellular componentcytosol
GO_0043231Cellular componentintracellular membrane-bounded organelle
GO_0005768Cellular componentendosome
GO_0032580Cellular componentGolgi cisterna membrane
GO_0019899Molecular functionenzyme binding
GO_0140312Molecular functioncargo adaptor activity
GO_0005515Molecular functionprotein binding
GO_0070273Molecular functionphosphatidylinositol-4-phosphate binding

IV. Literature review

[source]
Gene nameGOLPH3
Protein nameGolgi phosphoprotein 3
Golgi phosphoprotein 3 (Coat protein GPP34) (Mitochondrial DNA absence factor) (MIDAS)
Alternative protein GOLPH3
SynonymsGPP34
DescriptionFUNCTION: Phosphatidylinositol-4-phosphate-binding protein that links Golgi membranes to the cytoskeleton and may participate in the tensile force required for vesicle budding from the Golgi. Thereby, may play a role in Golgi membrane trafficking and could indirectly give its flattened shape to the Golgi apparatus. May also bind to the coatomer to regulate Golgi membrane trafficking. May play a role in anterograde transport from the Golgi to the plasma membrane and regulate secretion. Has also been involved in the control of the localization of Golgi enzymes through interaction with their cytoplasmic part. May play an indirect role in cell migration. Has also been involved in the modulation of mTOR signaling. May also be involved in the regulation of mitochondrial lipids biosynthesis. .

AccessionsQ9H4A6
L8ECJ6
ENST00000265070.7
D6REM1
ENST00000503610.5