EMB | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
natural killer cell	36 studies	27% ± 8%	Explore
CD8-positive, alpha-beta T cell	36 studies	29% ± 9%	Explore
T cell	29 studies	29% ± 9%	Explore
CD4-positive, alpha-beta T cell	27 studies	31% ± 10%	Explore
B cell	26 studies	22% ± 5%	Explore
regulatory T cell	25 studies	27% ± 8%	Explore
mature NK T cell	18 studies	30% ± 9%	Explore
memory B cell	17 studies	22% ± 5%	Explore
CD16-negative, CD56-bright natural killer cell, human	16 studies	30% ± 9%	Explore
classical monocyte	16 studies	29% ± 14%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	16 studies	26% ± 8%	Explore
gamma-delta T cell	16 studies	37% ± 7%	Explore
mucosal invariant T cell	15 studies	39% ± 10%	Explore
CD16-positive, CD56-dim natural killer cell, human	15 studies	29% ± 7%	Explore
plasmacytoid dendritic cell	14 studies	31% ± 11%	Explore
macrophage	13 studies	32% ± 12%	Explore
effector memory CD8-positive, alpha-beta T cell	13 studies	40% ± 9%	Explore
naive B cell	13 studies	21% ± 5%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	13 studies	29% ± 7%	Explore
CD8-positive, alpha-beta memory T cell	12 studies	40% ± 10%	Explore
CD4-positive, alpha-beta memory T cell	11 studies	34% ± 7%	Explore
myeloid cell	8 studies	33% ± 18%	Explore
retinal cone cell	7 studies	43% ± 19%	Explore
T follicular helper cell	7 studies	27% ± 5%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	6 studies	33% ± 9%	Explore
effector CD8-positive, alpha-beta T cell	6 studies	31% ± 5%	Explore
retinal ganglion cell	6 studies	45% ± 21%	Explore
dendritic cell	6 studies	27% ± 15%	Explore
effector memory CD4-positive, alpha-beta T cell	6 studies	38% ± 10%	Explore
central memory CD8-positive, alpha-beta T cell	5 studies	36% ± 13%	Explore
exhausted T cell	5 studies	36% ± 10%	Explore
effector CD4-positive, alpha-beta T cell	5 studies	33% ± 9%	Explore
leukocyte	5 studies	36% ± 16%	Explore
hematopoietic precursor cell	5 studies	36% ± 6%	Explore
lymphocyte	5 studies	44% ± 17%	Explore
precursor B cell	5 studies	24% ± 7%	Explore
innate lymphoid cell	5 studies	27% ± 6%	Explore
monocyte	4 studies	25% ± 7%	Explore
conventional dendritic cell	4 studies	43% ± 19%	Explore
pro-B cell	4 studies	26% ± 4%	Explore
CD4-positive helper T cell	4 studies	34% ± 10%	Explore
microglial cell	4 studies	30% ± 7%	Explore
CD4-positive, alpha-beta cytotoxic T cell	3 studies	25% ± 4%	Explore
neutrophil	3 studies	22% ± 8%	Explore
common myeloid progenitor	3 studies	25% ± 3%	Explore
enterocyte	3 studies	21% ± 7%	Explore
immature B cell	3 studies	20% ± 3%	Explore
mesothelial cell	3 studies	36% ± 9%	Explore
GABAergic neuron	3 studies	39% ± 10%	Explore
glutamatergic neuron	3 studies	51% ± 9%	Explore
group 3 innate lymphoid cell	3 studies	24% ± 8%	Explore
T-helper 17 cell	3 studies	32% ± 5%	Explore
T-helper 1 cell	3 studies	30% ± 10%	Explore
central memory CD4-positive, alpha-beta T cell	3 studies	34% ± 3%	Explore
double negative thymocyte	3 studies	40% ± 8%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
peripheral blood	16 studies	29% ± 11%	Explore
lung	3 studies	20% ± 2%	Explore
bone marrow	3 studies	28% ± 8%	Explore
intestine	3 studies	17% ± 1%	Explore
brain	3 studies	33% ± 7%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
thymus	100%	3404.06	652 / 653	99%	74.95	599 / 605
prostate	96%	1697.21	234 / 245	100%	81.38	502 / 502
lung	99%	2193.55	572 / 578	86%	42.25	995 / 1155
breast	88%	959.88	402 / 459	84%	29.27	937 / 1118
adrenal gland	99%	3422.64	255 / 258	43%	17.97	99 / 230
bladder	67%	505.00	14 / 21	66%	18.04	335 / 504
esophagus	58%	516.32	832 / 1445	74%	27.91	136 / 183
stomach	60%	484.64	216 / 359	71%	21.66	204 / 286
intestine	65%	1449.39	626 / 966	53%	16.46	278 / 527
skin	77%	2696.16	1385 / 1809	41%	10.26	193 / 472
pancreas	5%	35.98	18 / 328	95%	34.65	169 / 178
lymph node	0%	0	0 / 0	100%	48.17	29 / 29
spleen	100%	4901.10	241 / 241	0%	0	0 / 0
peripheral blood	99%	9305.38	924 / 929	0%	0	0 / 0
adipose	96%	2577.27	1154 / 1204	0%	0	0 / 0
kidney	34%	322.19	30 / 89	52%	10.13	473 / 901
ovary	16%	121.29	28 / 180	57%	11.13	247 / 430
tonsil	0%	0	0 / 0	71%	13.83	32 / 45
uterus	16%	114.07	28 / 170	53%	11.47	241 / 459
blood vessel	66%	859.26	880 / 1335	0%	0	0 / 0
heart	42%	398.29	365 / 861	0%	0	0 / 0
brain	18%	145.71	472 / 2642	19%	2.95	134 / 705
liver	7%	37.69	15 / 226	14%	3.19	55 / 406
eye	0%	0	0 / 0	3%	0.23	2 / 80
muscle	2%	13.31	17 / 803	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

III. Associated gene sets

GO_0007156	Biological process	homophilic cell adhesion via plasma membrane adhesion molecules
GO_0007411	Biological process	axon guidance
GO_0070593	Biological process	dendrite self-avoidance
GO_0035879	Biological process	plasma membrane lactate transport
GO_0030424	Cellular component	axon
GO_0045202	Cellular component	synapse
GO_0005886	Cellular component	plasma membrane
GO_0098632	Molecular function	cell-cell adhesion mediator activity

IV. Literature review

[source]

Gene name	EMB
Protein name	Embigin
Synonyms
Description	FUNCTION: Plays a role in the outgrowth of motoneurons and in the formation of neuromuscular junctions. Following muscle denervation, promotes nerve terminal sprouting and the formation of additional acetylcholine receptor clusters at synaptic sites without affecting terminal Schwann cell number or morphology. Delays the retraction of terminal sprouts following re-innervation of denervated endplates. May play a role in targeting the monocarboxylate transporters SLC16A1, SLC16A6 and SLC16A7 to the cell membrane (By similarity). .
Accessions	Q6PCB8 ENST00000508934.5 D6RDX7 ENST00000303221.10 [Q6PCB8-1] ENST00000514111.1 [Q6PCB8-2]

EMB report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review